Results 51 to 60 of about 2,661 (192)
Review of the Protective Mechanism of Paeonol on Cardiovascular Disease
Drug Design, Development and Therapy, 2023 Cardiovascular disease (CVD) is one of the leading causes of death in the world. Paeonol(Pae) is a phenolic component extracted from peony bark, peony root and Xu Changqing. Studies have shown that Pae can protect cardiomyocytes by inhibiting oxidative stress, promoting mitochondrial fusion, regulating mitochondrial autophagy and inhibiting ...
Yang,Chunkun +5 more
openaire +4 more sources
Paeonol Suppresses Bladder Cancer Progression via Apoptotic Pathways: Insights from In Vitro and In Vivo Studies. [PDF]
Pharmaceuticals (Basel)Background/Objectives: Bladder cancer (BC), a highly heterogeneous and mutation-prone malignancy, remains a significant therapeutic challenge due to its propensity for recurrence, metastasis, and drug resistance. Natural products, particularly paeonol, a
Ying L +8 more
europepmc +2 more sources
Neuroprotective Effect of Paeonol in the Rat Model of Traumatic Brain Injury
, 2020 Objectives:Traumatic brain injury (TBI) is a major cause of disability and mortality that induces oxidative stress and apoptosis causing cellular damage.
Emine Arık +8 more
core +1 more source
Chinese Journal of Physiology, 2023 Aberrant glycolytic reprogramming is involved in lung cancer progression by promoting the proliferation of non-small cell lung cancer cells. Paeonol, as a traditional Chinese medicine, plays a critical role in multiple cancer cell proliferation and ...
Lixin Zhang +4 more
doaj +1 more source
Pharmaceuticals, 2022 Methotrexate (MTX) is an effective chemotherapeutic agent against a wide range of tumors and autoimmune diseases; however, hepatotoxicity limits its clinical use.
Mohamed A. Morsy +4 more
doaj +1 more source
Action Potential Bursts in Central Snail Neurons Elicited by Paeonol: Roles of Ionic Currents
, 2011 Aim: To investigate the effects of 2'-hydroxy-4'- methoxyacetophenone ( paeonol) on the electrophysiological behavior of a central neuron (right parietal 4; RP4) of the giant African snail (Achatina fulica Ferussac). Methods: Intracellular recordings and
CHEN, YI-HUNG;LIN, PEI-LIN;YANG, HAN-YIN;LU, DAH-YUU;HUANG, SHIANG-SUO;LIN, JAUNG-GENG +1 more
core +1 more source
Preparation and Characterization of a Complex of Paeonol and Hydroxypropyl-β-cyclodextrin [PDF]
, 2015 Purpose: To improve the solubility of paeonol in water by complexing with hydroxypropyl-β-cyclodextrin (HP-β-CD) and also to characterize the physicochemical properties of the complex.Methods: The complex of paeonol and HP-β-CD was prepared by freeze ...
Li, Y +7 more
core +1 more source
Chemical structure of paeonol oxime.
, 2013 Paeonol oxime (PO) (1-[2-hydroxy-4-methoxy phenyl] ethanone oxime) was synthesized from paeonol.
Seung-Ae Kim (362333) +9 more
core +1 more source
Beneficial Effects Exerted by Paeonol in the Management of Atherosclerosis [PDF]
Oxidative Medicine and Cellular Longevity, 2018 Atherosclerosis, a chronic luminal stenosis disorder occurred in large and medium arteries, is the principle pathological basis of cardiovascular diseases with the highest morbidity and mortality worldwide. In oriental countries, traditional Chinese medicine Cortex Moutan has been widely used for the treatment of atherosclerosis‐related illnesses for ...
Li Lu +3 more
openaire +2 more sources
Paeonol inhibits profibrotic signaling and HOTAIR expression in fibrotic buccal mucosal fibroblasts
Journal of the Formosan Medical Association, 2022 Background/purpose: Betel nut chewing is the major risk factor of oral submucous fibrosis (OSF). Various studies have sought to discover alternative strategies to alleviate oral fibrogenesis.
Dennis Chun-Yu Ho +7 more
doaj +1 more source