Results 61 to 70 of about 146,504 (339)

Scalable production and biophysical characterization of an enzyme cocktail derived from human red blood cells

Biotechnology Progress, EarlyView.
Abstract Red blood cells (RBCs) play a critical role in oxygen and carbon dioxide transport, which is facilitated by RBC‐encapsulated hemoglobin (Hb) and carbonic anhydrase (CA). In addition, RBCs are constantly exposed to oxidative stress due to the intracellular reactive oxygen species (ROS) generated during Hb auto‐oxidation.
Mohd Asim Khan, Griffin J. Beyer, Naomi Goosby, Lilly Ortiz, Andre F. Palmer   +4 more
wiley   +1 more source

Targeting Platelet Activating Factor Signaling for Therapeutic Benefits in Neurodegenerative Disorders

Frontiers in Bioscience-Landmark
Neurodegenerative disorders (NDs), including dementia, Alzheimer’s disease (AD), and Parkinson’s disease (PD), are age-related diseases closely associated with chronic inflammation, oxidative stress, gene mutations, autoimmune-derived inflammation, and ...
Theodora Adamantidi, Andreas M. Grabrucker, Alexandros Tsoupras   +2 more
doaj   +1 more source

Platelet activating factor levels and metabolism in tangier disease: a case study

Lipids in Health and Disease, 2012
Background Tangier disease (TD) is a phenotypic expression of rare familial syndrome with mutations in the ABCA1 transporter. The risk of coronary artery disease in patients with TD is variable.
Kolovou Vana, Papakonstantinou Vasiliki D, Stamatakis George, Verouti Sophia N, Xanthopoulou Marianna N, Kolovou Genovefa, Demopoulos Constantinos A   +6 more
doaj   +1 more source

Selecting RNA aptamers for synthetic biology: investigating magnesium dependence and predicting binding affinity. [PDF]

, 2010
The ability to generate RNA aptamers for synthetic biology using in vitro selection depends on the informational complexity (IC) needed to specify functional structures that bind target ligands with desired affinities in physiological concentrations of ...
Carothers, James M, Goler, Jonathan A, Kapoor, Yuvraaj, Keasling, Jay D, Lara, Lesley   +4 more
core   +2 more sources

Research Progress of Polyoxometalate‐Integrated Frameworks: Syntheses, Properties, and Applications

ChemistryEurope, EarlyView.
This review systematically summarizes the integration of polyoxometalates with covalent organic frameworks, metal‐organic frameworks, hydrogen‐bonded organic frameworks, and emerging porous hosts. It highlights synergistic effects, synthesis strategies, and applications in catalysis, energy storage, sensing, and biomedicine, while addressing current ...
De‐Yin Wang, Zhang‐Di Liu, Rui Xing, Zi‐Hao Wei, Zaixiang Zhang, Yang Yang, Jin Zhu   +6 more
wiley   +1 more source

Improving seismic signal classification of different ground activities with advanced AI and signal processing techniques

Discover Geoscience
This study presents a comparative framework for seismic signal classification based on adaptive decomposition and Hilbert spectral analysis. A self-recorded vibration dataset containing approximately 4,500 one-second segments of pedestrian, bicycle, and ...
Abdul Moiz, Mohsin Jadoon, Sohaib Ahmad, Arshad Iqbal, Muhammad Bilal Qureshi   +4 more
doaj   +1 more source

Winery By-Products In Vitro and In Vivo Effects on Atherothrombotic Markers: Focus on Platelet-Activating Factor

Frontiers in Bioscience-Landmark
Platelet aggregation and inflammation play a crucial role in atherothrombosis. Wine contains micro-constituents of proper quality and quantity that exert cardioprotective actions, partly through inhibiting platelet-activating factor (PAF), a potent ...
Maria Choleva, Smaragdi Antonopoulou, Elizabeth Fragopoulou   +2 more
doaj   +1 more source

Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro- or anti-apoptotic signaling in primary neuronss⃞

Journal of Lipid Research, 2008
The platelet-activating factor (PAF) family of glycerophospholipids accumulates in damaged brain tissue following injury. Little is known about the role of individual isoforms in regulating neuronal survival.
Scott D. Ryan, Cory S. Harris, Casey L. Carswell, John E. Baenziger, Steffany A.L. Bennett   +4 more
doaj   +1 more source

Noncommutative Chiral Anomaly and the Dirac-Ginsparg-Wilson Operator [PDF]

, 2002
It is shown that the local axial anomaly in $2-$dimensions emerges naturally if one postulates an underlying noncommutative fuzzy structure of spacetime .
, A. Connes, A.P. Balachandran, A.P. Balachandran, A.P. Balachandran, A.P. Balachandran, B. Ydri, B.P. Dolan, Badis Ydri, C.-S. Chu, D. Karabali, D.A. Varshalovich, G. Immirzi, H. Aoki, H. Aoki, H. Grosse, H. Grosse, H. Grosse, H. Grosse, H. Grosse, H. Steinacker, J. Madore, J. Nishimura, K. Fujikawa, K. Fujikawa, P. Presnajder, P. Presnajder, S. Baez, S. Vaidya, S. Vaidya, S. Vaidya, U. Carow-Watamura, U. Carow-Watamura   +32 more
core   +2 more sources

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

Developmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa, Reina Muramatsu, Takaki Miyata   +2 more
wiley   +1 more source