Results 81 to 90 of about 24,664,088 (323)

Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia

open access: yesHypertension in Pregnancy, 2019
Objective: Investigating D-Dimer/D-Di and plasminogen activator inhibitor type-1/PAI-1 levels throughout gestation in women with preeclampsia/PE risk factors. Methods: D-Di and PAI-1 plasma levels were determined in 28 women at 12–19, 20–29, 30–34 and 35–
Flávia Campos Lucena   +9 more
doaj   +1 more source

A non-lethal traumatic/hemorrhagic insult strongly modulates the compartment-specific PAI-1 response in the subsequent polymicrobial sepsis.

open access: yesPLoS ONE, 2013
IntroductionPlasminogen activator inhibitor 1 (PAI-1) is a key factor in trauma- and sepsis-induced coagulopathy. We examined how trauma-hemorrhage (TH) modulates PAI-1 responses in subsequent cecal ligation and puncture (CLP)-induced sepsis, and the ...
Pierre Raeven   +7 more
doaj   +1 more source

uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies

open access: yesBreast Cancer Research, 2014
Urokinase plasminogen activator (uPA) is an extracellular matrix-degrading protease involved in cancer invasion and metastasis, interacting with plasminogen activator inhibitor-1 (PAI-1), which was originally identified as a blood-derived endogenous fast-
M. Duffy   +4 more
semanticscholar   +1 more source

Polymorphisms of plasminogen activator inhibitor-1, angiotensin converting enzyme and coagulation factor XIII genes in patients with recurrent spontaneous abortion [PDF]

open access: yes, 2011
We investigated polymorphisms of plasminogen activator inhibitor-1 (PAI-1), angiotensin converting enzyme (ACE ) and coagulation factor XIII (FXIII) genes and their association with recurrent spontaneous abortion (RSA) in Iranian patients and normal ...
Aarabi, M.   +6 more
core  

Unique secretory dynamics of tissue plasminogen activator and its modulation by plasminogen activator inhibitor-1 in vascular endothelial cells [PDF]

open access: yes, 2009
We analyzed the secretory dynamics of tissue plasminogen activator (tPA) in EA.hy926 cells, an established vascular endothelial cell (VEC) line producing GFP-tagged tPA, using total internal reflection fluorescence (TIR-F) microscopy.
2722   +7 more
core   +2 more sources

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

Korelacija aktivnosti PAI-1 u plazmi i polimorfizma 4G/5G u genu za PAI-1 [PDF]

open access: yes, 2016
Hemostaza obuhvaća složene, međusobno povezane sustave čija je zadaća održati fluidnost krvi u tekućem stanju u krvožilnom sustavu, ali i omogućiti brzo stvaranje krvnog ugruška nakon ozljede krvne žile.
Čolić, Merima
core   +1 more source

All‐Hydrogel‐Based Organic Electrochemical Transistors for Implantable Physiological Signal Monitoring

open access: yesAdvanced Science, EarlyView.
All‐hydrogel based n‐type depletion‐mode OECTs is developed using a semiconductor hydrogel formed via ionic‐liquid‐mediated phase separation, combining efficient ion‐electron transport, tissue‐like softness, and long‐term biocompatibility. The device can monitor EOG and ECG on human skin and record real‐time ECG subcutaneously in rats, providing a ...
Qicheng Liang   +14 more
wiley   +1 more source

The Astragaloside IV Derivative LS-102 Ameliorates Obesity-Related Nephropathy

open access: yesDrug Design, Development and Therapy, 2022
Ziyu Li,1 Wei Yang,1 Yong Yang,1 Jianbo Wu,2 Pei Luo,3 Yong Liu1,4,5 1Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 2Drug Discovery Research Center, Southwest Medical ...
Li Z, Yang W, Yang Y, Wu J, Luo P, Liu Y
doaj  

Interactive Effect of PAI-1 4G/5G Genotype and Salt Intake on PAI-1 Antigen [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2001
Abstract —Activation of the renin-angiotensin-aldosterone system (RAAS) is associated with increased circulating PAI-1 antigen and increased risk of thrombotic cardiovascular events. A 4G/5G polymorphism located 675 bp upstream from the transcription start site of the PAI-1 gene affects PAI-1 antigen ...
N J, Brown   +5 more
openaire   +2 more sources

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