Results 91 to 100 of about 466,886 (231)

Follow-up study of sensory-motor polyneuropathy in Type 1 (insulin-dependent) diabetic subjects after simultaneous pancreas and kidney transplantation and after graft rejection [PDF]

, 1991
The influence of successful simultaneous pancreas and kidney transplantation on peripheral polyneuropathy was investigated in 53 patients for a mean observation period of 40.3 months. Seventeen patients were followed-up for more than 3 years.
Illner, Wolf-Dieter, Wagner, S., Nusser, J., Müller-Felber, W., Landgraf-Leurs, M. M. C., Land, Walter, Landgraf, R., Abendroth, D., Mair, N.   +8 more
core   +1 more source

Real‐World Effectiveness and Safety of Tirzepatide in Type 1 Diabetes and Obesity: Impact on Glycaemia, Weight, and Cardiometabolic Risk Markers

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8836-8846, October 2026.
ABSTRACT Aims To evaluate the effectiveness and safety of tirzepatide on glycaemia, weight, and markers of cardiometabolic risk in people with type 1 diabetes and obesity. Materials and Methods This retrospective cohort study compared 142 adults with type 1 diabetes (BMI ≥ 30 kg/m2) initiated on tirzepatide against 50 age‐, sex‐ and BMI‐matched ...
Simon A. Berry, Iona R. Goodman, Eleanor McNally, Jackie Elliott, Ahmed Iqbal   +4 more
wiley   +1 more source

Assessment of Pain Characteristics, Attribution, and Nociplasticity in Patients With Inflammatory Myopathies: An International Survey Study

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective Idiopathic inflammatory myopathies (IIMs) have historically been viewed to cause painless weakness and are therefore poorly understood. We aimed to report pain characteristics in patients with IIMs and estimate the contributions of fibromyalgia and common painful comorbidities to pain intensity.
Mohammad Radaideh, Juan Schmukler, Alexander Best, Joshlean Fair, Manuel Lubinus, Yvonne C. Lee, Didem Saygin   +6 more
wiley   +1 more source

Guidelines in the management of diabetic nerve pain clinical utility of pregabalin

Diabetes, Metabolic Syndrome and Obesity, 2013
Aaron I Vinik, Carolina M Casellini Strelitz Diabetes Center for Endocrine and Metabolic Disorders, Eastern Virginia Medical School, Norfolk, VA, USA Abstract: Diabetic peripheral neuropathy is a common complication of diabetes.
Vinik AI, Casellini CM
doaj  

Efficacy and Safety of Trazodone and Gabapentin Fixed-Dose Combination in Patients Affected by Painful Diabetic Neuropathy: Randomized, Controlled, Dose-Finding Study

Pain and Therapy
Introduction Up to 50% of diabetic patients with neuropathy suffer from chronic pain, namely painful diabetic neuropathy (PDN), an unmet medical need with significant impact on quality of life. Gabapentin is widely used for PDN, albeit with frequent dose-
Solomon Tesfaye, Ponnusamy Saravanan, Edvard Ehler, Karel Zinek, Ilona Palka-Kisielowska, Marcin Nastaj, Pierre Serusclat, Paola Lipone, Andrea Vergallo, Elisa Quarchioni, Fabrizio Calisti, Alessandro Comandini, Agnese Cattaneo   +12 more
doaj   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, Volume 100, Issue 3, Page 458-476, September 2026.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Antidepresivos de nueva generación en neuropatía diabética dolorosa

Revista Ciencias de la Salud, 2011
The incidence of diabetic neuropathy increases with the duration of diabetes and the degree of hyperglycaemia. Pain is one of the mostcommon and incapacitating symptoms of diabetic neuropathy and itspharmacological control is complex.
Ángela M. Gutiérrez-Álvarez, Carlos B. Moreno   +1 more
doaj  

When Glycaemic Control Comes Too Fast: Treatment‐Induced Neuropathy of Diabetes and Charcot Neuro‐Osteoarthropathy as Emerging Iatrogenic Complications of Rapid Metabolic Correction

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Purpose of Review Diabetes therapeutics can lower glycated haemoglobin (HbA1c) by several percentage points within weeks. While long‐term microvascular risk is reduced by improved glycaemia, abrupt metabolic transitions may destabilise tissues adapted to chronic hyperglycemia.
Dured Dardari
wiley   +1 more source

Global Epidemiology of Diabetic Foot: A Systematic Review and Meta‐Analysis

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Introduction Diabetic foot (DF) disease, including ulcerations, amputations, and infections, represents a major cause of morbidity and mortality in individuals with diabetes mellitus (DM). Despite their substantial clinical, social, and economic burden, robust global epidemiological estimates remain limited due to fragmented evidence and ...
Massimo Carollo, Ylenia Ingrasciotta, Salvatore Crisafulli, Francesco Maccarrone, Daniela Pellegrino, Alberto Francescon, Edoardo Mannucci, Andrea Fontana, Gianluca Trifirò   +8 more
wiley   +1 more source

Distal sensory polyneuropathy in HIV/TB co-infection : the role of vitamin B6 and N-acetyltransferase 2 genetic variation [PDF]

, 2012
Both human immunodeficiency virus (HIV) infection and tuberculosis (TB) are complicated by a painful distal sensory polyneuropathy (DSP) that may be due to virus-related HIV-DSP, antiretroviral toxic neuropathy (ATN) or isoniazid-induced peripheral ...
Centner, Chad
core   +1 more source