Results 71 to 80 of about 466,886 (231)

Bridging gaps in diabetic neuropathy care: A Delphi‐based regional consensus from the Gulf Cooperation Council

Journal of Diabetes Investigation, EarlyView.
A three‐round Delphi consensus developed GCC‐specific, evidence‐based recommendations for diabetic peripheral neuropathy (DPN) and painful diabetic neuropathy (PND). The consensus emphasizes proactive screening, early multimodal management, and addressing regional barriers to improve early detection, optimize management, and enhance quality of life ...
Abdulrahman Alshaikh, Abdulnabi T Alattar, Ahmed Abdul Karim Hassoun, Afaf Alshammary, Hussein Elbadawi, Khaled Aldossari, Noor Al Busaidi, Saud Alsifri, Talal Muzaffar, Wiam I. Hussein, Christine Talaat, Abanoub Effat, Marwa Elsaghier, Rayaz A Malik   +13 more
wiley   +1 more source

Inflammation, mechanical allodynia and an exaggerated exercise pressor reflex during disease progression in UCD‐type 2 diabetes mellitus rats

Experimental Physiology, EarlyView.
Abstract Chronic low‐grade inflammation characterizes type 2 diabetes mellitus (T2DM) and underlies the development of peripheral neuropathy, symptoms of which include mechanical allodynia and an exaggerated exercise pressor reflex. The purpose of this study was to determine whether mechanical allodynia and/or specific concentrations of inflammatory ...
Michelle L. Harrison, Richard K. McCuller, Yu Huo, Amshula N. Gajula, Kai Ybarbo, Mark J. Van Ryzin, Kimber L. Stanhope, Peter J. Havel, Audrey J. Stone   +8 more
wiley   +1 more source

Painful Diabetic Neuropathy [PDF]

, 2016
Pain-sensing sensory neurons (nociceptors) of the dorsal root ganglia (DRG) and dorsal horn (DH) can become sensitized (hyperexcitable) in response to pathological conditions such as diabetes, which in turn may lead to the development of painful peripheral diabetic neuropathy (PDN).
openaire   +2 more sources

Acute lower leg transcutaneous electrical nerve stimulation increases leg blood flow and exercise capacity in patients with peripheral arterial disease

Experimental Physiology, EarlyView.
Abstract We tested the hypothesis that two different durations of lower leg transcutaneous electrical nerve stimulation (TENS) increase post‐TENS popliteal artery blood flow (PABF), popliteal vascular conductance (PVC), and 6‐min walk distance (6MWD) in patients with peripheral artery disease (PAD).
Thomas K. Pellinger, Catherine B. Neighbors, Joshua C. Hefta, Patrick H. Luo, Carl B. Suarez, Erotokritos T. Varlas, Grant H. Simmons, Brett J. Wong   +7 more
wiley   +1 more source

Pharmacologic interventions for painful diabetic neuropathy: an umbrella systematic review and comparative effectiveness network meta-analysis (Protocol)

Systematic Reviews, 2012
Background Neuropathic pain can reduce the quality of life and independence of 30% to 50% of patients with diabetes. The comparative effectiveness of analgesics for patients with diabetic neuropathy remains unclear. The aim of the current work, therefore,
Griebeler Marcio L, Tsapas Apostolos, Brito Juan P, Wang Zhen, Phung Olivia J, Montori Victor M, Murad M   +6 more
doaj   +1 more source

Women with a history of gestational diabetes mellitus have preserved sensory nerve‐mediated dilatation in the cutaneous microvasculature

Experimental Physiology, EarlyView.
Abstract Women with a history of gestational diabetes mellitus (GDM) have a greater risk of developing type 2 diabetes mellitus and cardiovascular disease than healthy control (HC) women who had an uncomplicated pregnancy. Microvascular endothelial dysfunction, mediated by reduced nitric oxide (NO)‐dependent mechanisms, persists after GDM.
Grace S. Maurer, Kelsey S. Schwartz, Diana I. Jalal, Anna E. Stanhewicz   +3 more
wiley   +1 more source

Painful diabetic neuropathies, cases report and diagnostic criteria [PDF]

Pathos, 2006
Painful diabetic neuropathy is a model for the investigation of drug’s efficacy in neuropathic pain. Diabetes, through multiple pathophysiological mechanisms causes several painful neuropathies.
Marco Lacerenza
doaj  

Mechanical sensitization of sensory afferents after passive transfer of fibromyalgia IgG

The Journal of Physiology, EarlyView.
Abstract figure legend In addition to widespread pain and fatigue, people with fibromyalgia (FM) experience sensory abnormalities and report lingering, painful sensations after touch or mechanical probing of the skin. Administration of IgG purified from FM patients to mice transfers symptoms and signs of FM.
Mathilde R. Israel, Nisha Vastani, Clive Gentry, Andreas Goebel, Stuart Bevan, David A. Andersson   +5 more
wiley   +1 more source

Decompression nerve surgery for diabetic neuropathy: a structured review of published clinical trials

Diabetes, Metabolic Syndrome and Obesity, 2018
James W Albers,1 Ryan Jacobson2 1Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; 2Department of Neurology, Rush University Medical Center, Chicago, IL, USA Aim: To assess lower extremity decompression nerve surgery ...
Albers JW, Jacobson R
doaj  

Is resistance to ischaemia of motor axons in diabetic subjects due to membrane depolarization? [PDF]

, 1990
The reasons for the resistance to ischaemia of peripheral nerves in diabetics are not well understood. We have now explored whether axonal depolarization underlies this phenomenon, as has previously been proposed.
Weigl, Paul, Piwernetz, Klaus, Strupp, Michael, Bostock, Hugh, Grafe, Peter, Renner, Rolf   +5 more
core   +1 more source