Results 81 to 90 of about 11,356 (208)
Continuum of physical behavior changes and important questions about exercise prescription approach in the diabetes context. ABSTRACT Although physical exercise is widely recognized for its role in glycemic control and overall health, population characteristics such as comorbidities, sedentary behavior, disease‐related complications, and socioeconomic ...
Rodrigo Sudatti Delevatti +2 more
wiley +1 more source
Antidepresivos de nueva generación en neuropatía diabética dolorosa
The incidence of diabetic neuropathy increases with the duration of diabetes and the degree of hyperglycaemia. Pain is one of the mostcommon and incapacitating symptoms of diabetic neuropathy and itspharmacological control is complex.
Ángela M. Gutiérrez-Álvarez +1 more
doaj
Consensus on the Clinical Use of Pregabalin in Peripheral Neuropathic Pain
Pregabalin, a second‐generation α2δ calcium‐channel ligand, exerts potent analgesic effects in peripheral neuropathic pain by reducing calcium influx, suppressing excitatory neurotransmitter release, and decreasing neuronal hyperexcitability. Based on a PRISMA‐guided review of 139 studies and multidisciplinary expert consensus, pregabalin demonstrates ...
Hui Lu +22 more
wiley +1 more source
Docking analyses were performed for Neocuproine/Trolox. In comparison to the sham group, IL‑1β and TNF‐α levels in spinal cord and cortex tissues were higher, while IL‑10 and TGF‐β levels were lower. Neocuproine/Trolox treatments reduced proinflammatory cytokine levels and elevated anti‐inflammatory cytokine levels in CCI rats on day 14.
Selma Yaman +3 more
wiley +1 more source
About 20% of patients with diabetes suffer from chronic pain with neuropathic characteristics. We investigated the multivariate associations between 92 neurology-related proteins measured in serum from 190 patients with painful and painless diabetic ...
Emmanuel Bäckryd +7 more
doaj +1 more source
Things We Do for No Reason™: Prescribing gabapentinoids for pain
Visual Abstract Abstract Gabapentin and pregabalin are among the most frequently prescribed medications in the United States, with gabapentin in the top 10 and pregabalin in the top 100. Despite FDA approval for only select neuropathic conditions, most use is for off‐label pain indications.
Niti G. Patel +4 more
wiley +1 more source
Phylogenetic Profiling of the Diabetic Foot Ulcer Microbiome of an Afro‐Caribbean Population
Illumina amplicon sequencing revealed diverse bacterial and fungal communities in chronic diabetic foot ulcers (DFUs) and adjacent normal skin from Afro‐Caribbean patients. Corynebacterium striatum dominated both sites. DFUs had higher relative abundance of Pseudomonas aeruginosa and the antifungal‐resistant Candida duobushaemulonii, with significantly
Nkemcho Ojeh +9 more
wiley +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Nanjing Consensus II on Washed Microbiota Transplantation: Statements From the CHINAGUT Conference
ABSTRACT The new method of fecal microbiota transplantation, based on automatic facilities and washing processes, was coined as washed microbiota transplantation (WMT). The first recommendations on WMT were released as Nanjing Consensus report by the fecal microbiota transplantation (FMT)‐standardization Study Group in 2019.
Faming Zhang +53 more
wiley +1 more source
ABSTRACT Objective To examine the acute effect of a self‐regulated dual‐task during resistance exercise on muscular endurance, pain intensity and pressure pain threshold (PPT) in patients undergoing carpal tunnel release (CTR). Methods Participants were randomly assigned to resistance exercise combined with a self‐regulated cognitive task (dual‐task ...
Rodrigo Núñez‐Cortés +9 more
wiley +1 more source

