Results 81 to 90 of about 466,886 (231)

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Molecular factors involved in the development of diabetic foot syndrome [PDF]

, 2012
Diabetes is one of the major challenges of modern medicine, as it is considered a global epidemic of the XXI century. The disease often leads to the development of serious, health threatening complications.
Brun-Olszewska, Bożena, Olszewski, Paweł, Bruhn-Olszewska, Bożena, Węgrzyn, Alicja, Gabig-Cimińska, Magdalena, Korzon-Burakowska, Anna, Jakóbkiewicz-Banecka, Joanna   +6 more
core   +2 more sources

Spinal Disinhibition in Experimental and Clinical Painful Diabetic Neuropathy [PDF]

, 2017
Impaired rate dependent depression (RDD) of the Hoffman-reflex is associated with reduced dorsal spinal cord potassium chloride co-transporter expression and impaired spinal GABAA receptor function, indicative of spinal inhibitory dysfunction.
Michael Zhang, Fadavi, Hassan, Marshall, Andrew G, Ponirakis, Georgios, Ferdousi, Maryam, Malik, Rayaz A, Teresa Mixcoatl-Zecuatl, Katie Frizzi, Mixcoatl-Zecuatl, Teresa, Zhang, Michael, Efron, Nathan, Andrew G. Marshall, Hassan Fadavi, Maria Jeziorska, Calcutt, Nigel A, Corinne Lee-Kubli, Mitra Tavakoli, Maryam Ferdousi, Georgios Ponirakis, Corinne G. Jolivalt, Nigel A. Calcutt, Shazli Azmi, Azmi, Shazli, Ferdousi, Maryam; id_orcid, Andrew J.M. Boulton, Rayaz A. Malik, Frizzi, Katie, Lee-Kubli, Corinne, Jeziorska, Maria, Boulton, Andrew JM, Jolivalt, Corinne G, Ioannis N. Petropoulos, Fineman, Mark S, Nathan Efron, Mark S. Fineman, Petropoulos, Ioannis N, Tavakoli, Mitra, Boulton, Andrew J M   +37 more
core   +1 more source

Concurrent Long Thoracic and Lateral Cutaneous Intercostal Nerve Entrapment After Chest Tube Thoracostomy Causing Scapular Winging and Chest Wall Pain: Diagnosis With Ultrasound and Treatment With Hydrodissection

Pain Practice, Volume 26, Issue 8, November 2026.
ABSTRACT Background Chest tube thoracostomy may cause iatrogenic nerve injury, resulting in persistent pain and functional impairment. Long thoracic nerve (LTN) palsy after chest tube placement has been described, but concurrent involvement of the LTN and the lateral cutaneous branch of an intercostal nerve (LCIN) appears to be rarely reported.
Yonghyun Yoon, King Hei Stanley Lam, Daniel Chiung‐Jui Su, Teinny Suryadi, Anwar Suhaimi   +4 more
wiley   +1 more source

Local sympathetic denervation in painful diabetic neuropathy.

, 2002
This study assessed whether painful diabetic neuropathy is associated with abnormal sympathetic nervous function in the affected limbs. Nine patients with diabetes (four men, five women; age 61 +/- 7 years) and painful peripheral neuropathy of the feet ...
Tack, C.J.J., Gurp, P.J.M. van, Goldstein, D.S., Holmes, C.   +3 more
core   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2289-2308, October 2026.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

A multicenter study on the prevalence of diabetic neuropathy in Italy. Italian Diabetic Neuropathy Committee.

, 1997
The prevalence of neuropathy, a common complication of diabetes, was determined in diabetic patients recruited from 109 outpatient diabetes clinics in Italy.Neuropathy was diagnosed using the Diabetic Neuropathy Index (DNI), a standardized examination ...
P. Negrin, Cucinotta D., CUCINOTTA, Domenico Maria, D. Fedele, F. Santeusanio Appendix: Italian Diabetic Neuropathy Committee: ........ . Carducci D., . . . . ., G. Ghirlanda, C. Coscelli, GIRLANDA, Paolo, E. L. Feldman, G. Comi, D. A. Greene   +11 more
core  

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3333-3353, October 2026.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

Improvement in Neuropathy Specific Quality of Life in Patients with Diabetes after Vitamin D Supplementation

Journal of Diabetes Research, 2017
Objective. To assess the effect of vitamin D supplementation on neuropathy specific quality of life (NeuroQoL) in patients with painful diabetic neuropathy. Methods.
Uazman Alam, Asher Fawwad, Fariha Shaheen, Bilal Tahir, Abdul Basit, Rayaz A. Malik   +5 more
doaj   +1 more source

The Role of the Antidepressants in Managing Chemotherapy‐Induced Neuropathic Pain: A Systematic Review

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From symptom relief to multimodal care: duloxetine and amitriptyline may reduce established CIPN‐related pain and provide a therapeutic foundation for future combination strategies. ABSTRACT Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and debilitating complication of cancer treatment, characterized by neuropathic pain, sensory ...
Rosamaria Caminiti, Valeria Mazza, Saverio Nucera, Francesca Oppedisano, Lucia Carmela Passacatini, Jessica Maiuolo, Valentina Malafoglia, Alessandro Giorgio, Andrea Soluri, Claudia Pileggi, Carlo Tomino, Vincenzo Mollace, Sara Ilari, Carolina Muscoli   +13 more
wiley   +1 more source