Results 61 to 70 of about 11,356 (208)

Mechanical sensitization of sensory afferents after passive transfer of fibromyalgia IgG

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In addition to widespread pain and fatigue, people with fibromyalgia (FM) experience sensory abnormalities and report lingering, painful sensations after touch or mechanical probing of the skin. Administration of IgG purified from FM patients to mice transfers symptoms and signs of FM.
Mathilde R. Israel   +5 more
wiley   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Peripheral Polyneuropathy and Cognitive Impairment in Type II Diabetes Mellitus

open access: yesNeuropsychiatric Disease and Treatment, 2021
Rasha Elbialy Elsharkawy,1 Ghada Saed Abdel Azim,1 Marwa Abdellah Osman,1 Hend Maghraby Maghraby,2 Rehab Abdelfattah Mohamed,2 Eman Mahmoud Abdelsalam,2 Eman Elshohat Ebrahem,3 Nora Mohamed Ahmed Seliem3 1Department of Neurology, Faculty of Medicine for ...
Elsharkawy RE   +7 more
doaj  

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Volume 78, Issue 7, Page 860-874, July 2026.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

A Multispecies Systematic and Critical Review of Intranasal Administration in Veterinary Anaesthesia and Emergency Care: Promising Evidence and Overlooked Challenges

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This review evaluates the clinical potential and limitations of intranasal (IN) drug administration in veterinary anaesthesia and emergency care. IN delivery can provide clinically relevant sedation, analgesia and drug reversal, but its success is not universally reliable and is strongly influenced by species‐specific anatomy, formulation ...
Majid Jafarbeglou
wiley   +1 more source

TrkA abundance is increased in cutaneous nerves in bortezomib‐induced neuropathy

open access: yesBrain Pathology, Volume 36, Issue 4, July 2026.
Cutaneous nerves in bortezomib‐induced peripheral neuropathy (BIPN) show reduced nerve fiber density, increased TrkA expression, and enhanced dermal angiogenesis, highlighting a pathological switch in NGF/TrkA signaling that may contribute to nerve damage and pain. Abstract Tropomyosin receptor kinase A (TrkA), a high‐affinity receptor for nerve growth
Yuying Jin   +14 more
wiley   +1 more source

Pharmacologic interventions for painful diabetic neuropathy: an umbrella systematic review and comparative effectiveness network meta-analysis (Protocol)

open access: yesSystematic Reviews, 2012
Background Neuropathic pain can reduce the quality of life and independence of 30% to 50% of patients with diabetes. The comparative effectiveness of analgesics for patients with diabetic neuropathy remains unclear. The aim of the current work, therefore,
Griebeler Marcio L   +6 more
doaj   +1 more source

Prevalence and Correlates of Reporting a Gabapentin Prescription for Pain Among People Who Use Opioids: A Longitudinal Community‐Recruited Study

open access: yesDrug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Gabapentin is widely prescribed off‐label to treat pain. However, there are concerns about the proliferation of medical and non‐medical use, and the potential increased risk of overdose death associated with concurrent opioid use.
Evelyne Marie Piret   +7 more
wiley   +1 more source

Painful diabetic neuropathies, cases report and diagnostic criteria [PDF]

open access: yesPathos, 2006
Painful diabetic neuropathy is a model for the investigation of drug’s efficacy in neuropathic pain. Diabetes, through multiple pathophysiological mechanisms causes several painful neuropathies.
Marco Lacerenza
doaj  

Language matters: Guidance for person‐centred diabetes communication in Ireland

open access: yesDiabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Background/Aims Language is a powerful tool that shapes how people experience diabetes, their engagement with care and ultimately their outcomes. This guidance document for healthcare professionals in Ireland outlines why Language Matters in diabetes care and aims to support person‐centred, strengths‐based and non‐judgemental communication ...
C. Breen   +22 more
wiley   +1 more source

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