Results 41 to 50 of about 466,886 (231)
ANTINOCICIPTIVE EFFECT OF GINGER EXTRACT IN STREPTOZOTOCIN-INDUCED DIABETIC RATS [PDF]
Assiut Veterinary Medical Journal, 2012 Hyperalgesia is one of the major symptoms of diabetic neuropathy in diabetic patients. Streptozotocin (STZ)-induced diabetic rats display exaggerated hyperalgesic behavior in response to noxious stimuli, and the most commonly employed animal model aspect
M. ABDEL DAIM
doaj +1 more source
Nutritional optic and peripheral neuropathy: a case report. [PDF]
, 2009 INTRODUCTION: The link between nutritional status and either optic or peripheral neuropathies is well established with tobacco, ethanol, deficiencies in thiamine, vitamin A, B12, B3 and B6 and protein-energy malnutrition all being causative.
Nightingale, LM +3 more
core +1 more source
Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients
Annals of Neurology, EarlyView.Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer +14 more
wiley +1 more source
Translational development of crisugabalin for neuropathic pain
British Journal of Clinical Pharmacology, EarlyView.Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João +5 more
wiley +1 more source
Diagnosing and managing diabetic somatic and autonomic neuropathy
Therapeutic Advances in Endocrinology and Metabolism, 2019 The diagnosis and management of diabetic neuropathy can be a major challenge. Late diagnosis contributes to significant morbidity in the form of painful diabetic neuropathy, foot ulceration, amputation, and increased mortality.
Shazli Azmi +13 more
doaj +1 more source
BMEMat, EarlyView.To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv +3 more
wiley +1 more source
Acupuncture for painful diabetic neuropathy
Rinsho Shinkeigaku, 2012 In the present study I investigated the effects of acupuncture treatment on the pain of diabetic neuropathy and parsesthesia as well as the duration of the morbidity and treatment results. The study examined subjective symptoms associated with diabetic neuropathy (like spontaneous pain and parsesthesia) in 38 patients (divided into a 20-patient group ...
openaire +3 more sources
Gait Variability and Kinematic Alterations in People with Diabetes Mellitus and Peripheral Neuropathy [PDF]
Background: People with diabetes and peripheral neuropathy have been reported to show alterations in lower limb joint function compared to healthy non-diabetic people.
Bowling, Frank
core +3 more sources
Therapeutic Advances in Endocrinology and Metabolism, 2010 Diabetic neuropathy is common, under or misdiagnosed, and causes substantial morbidity with increased mortality. Defining and developing sensitive diagnostic tests for diabetic neuropathy is not only key to implementing earlier interventions but also to ...
Mitra Tavakoli +5 more
doaj +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source