Results 21 to 30 of about 11,356 (208)

Surgical decompression of painful diabetic peripheral neuropathy: the role of pain distribution. [PDF]

PLoS ONE, 2014
To investigate the effect of surgical decompression on painful diabetic peripheral neuropathy (DPN) patients and discuss the role which pain distribution and characterization play in the management of painful DPN as well as the underlying mechanism ...
Chenlong Liao, Wenchuan Zhang, Min Yang, Qiufeng Ma, Guowei Li, Wenxiang Zhong   +5 more
doaj   +1 more source

Sympathetic Blocks Provided Sustained Pain Relief in a Patient with Refractory Painful Diabetic Neuropathy

Case Reports in Anesthesiology, 2012
The sympathetic nervous system has been implicated in pain associated with painful diabetic neuropathy. However, therapeutic intervention targeted at the sympathetic nervous system has not been established.
Jianguo Cheng, Anuj Daftari, Lan Zhou
doaj   +1 more source

Pathogenesis of Painful Diabetic Neuropathy [PDF]

Pain Research and Treatment, 2014
The prevalence of diabetes is rising globally and, as a result, its associated complications are also rising. Painful diabetic neuropathy (PDN) is a well-known complication of diabetes and the most common cause of all neuropathic pain. About one-third of all diabetes patients suffer from PDN.
Amir Aslam, Jaipaul Singh, Satyan Rajbhandari   +2 more
openaire   +3 more sources

mTOR activation due to APPL1 deficiency exacerbates hyperalgesia via Rab5/Akt and AMPK signaling pathway in streptozocin-induced diabetic rats

Molecular Pain, 2019
Painful diabetic neuropathy is a common complication of diabetes mellitus with obscure underlying mechanisms. The adaptor protein APPL1 is critical in mediating the insulin sensitizing and insulin signaling.
Wan-You He, Bin Zhang, Wei-Cheng Zhao, Jian He, Yunhua Wang, Lei Zhang, Qing-Ming Xiong, Han-Bing Wang   +7 more
doaj   +1 more source

An Insight into Potential Pharmacotherapeutic Agents for Painful Diabetic Neuropathy

Journal of Diabetes Research, 2022
Diabetes is the 4th most common disease affecting the world’s population. It is accompanied by many complications that deteriorate the quality of life. Painful diabetic neuropathy (PDN) is one of the debilitating consequences of diabetes that effects one-
Zunaira Qureshi, Murtaza Najabat Ali, Minahil Khalid   +2 more
doaj   +1 more source

The prevalence of painful diabetic neuropathy in 300 Moroccan diabetics

The Pan African Medical Journal, 2018
Painful diabetic neuropathy is a frequent complication of diabetes. Its diagnosis is clinical. Our goal is to determine the prevalence of painful diabetic neuropathy in this population.
Zakaria Chahbi, Bouchra Lahmar, Sanae El Hadri, Lahoussaine Abainou, Said Kaddouri, Hassan Qacif, Hicham Baizri, Mohamed Zyani   +7 more
doaj   +1 more source

Capsaicin 8% Patch for Alternative Therapy of Painful Diabetic Peripheral Neuropathy

WMJ (Warmadewa Medical Journal), 2021
Diabetes is one of the most common health problems due to its high incidence and complications. One of the complications associated with diabetes is painful diabetic peripheral neuropathy (PDPN).
Muhammad Luthfi Adnan
doaj   +1 more source

Primary care incidence and treatment of four neuropathic pain conditions: A descriptive study, 2002–2005

BMC Family Practice, 2008
Background Between 1992 and 2001 the UK general practice incidence of post-herpetic neuralgia and trigeminal neuralgia declined, whilst the incidence of painful diabetic neuropathy increased. The most common first line treatments were compound analgesics.
Carroll Dawn, Hall Gillian C, McQuay Henry J   +2 more
doaj   +1 more source

High leukotriene B4 serum levels increase risk of painful diabetic neuropathy among type 2 diabetes mellitus patients

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Painful diabetic neuropathy is one of the most common complications of type 2 diabetes mellitus, with approximately 30–50% of people will experience diabetic neuropathy.
Kelvin Yuwanda, I Putu Eka Widyadharma, Dewa Putu Gde Purwa Samatra, I Made Oka Adnyana, Anna Marita Gelgel, I Komang Arimbawa   +5 more
doaj   +1 more source

Metformin Use Is Not Associated With B12 Deficiency or Neuropathy in Patients With Type 2 Diabetes Mellitus in Qatar

Frontiers in Endocrinology, 2018
BackgroundMetformin may lead to B12 deficiency and neuropathy. There are no published data on the prevalence of Metformin-related B12 deficiency and neuropathy in the Arabian Gulf.AimsDetermine whether Metformin intake is associated with B12 deficiency ...
Tarik Elhadd, Tarik Elhadd, Georgios Ponirakis, Zeinab Dabbous, Mashhood Siddique, Subitha Chinnaiyan, Rayaz A. Malik, Rayaz A. Malik   +7 more
doaj   +1 more source