Results 31 to 40 of about 466,886 (231)

A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain [PDF]

, 2014
Background: Neuropathic pain, caused by a lesion or a disease affecting the somatosensory system, is one of the most common complications in diabetic patients.
Palmer, C. N. A.; id_orcid, H.M. Colhoun, C.N.A. Palmer, Colhoun, H. M., L.A. Donnelly, Liu, Y., Zhou, K., Palmer, C. N A, van Zuydam, N. R., Smith, B. H.; id_orcid, H.A. Deshmukh, N.R. van Zuydam, K. Zhou, A.D. Morris, Donnelly, L. A., Deshmukh, H. A., Morris, A. D., Meng, W., Smith, B. H., Y. Liu, B.H. Smith, W. Meng   +21 more
core   +1 more source

Neuropathy - pain damage and the diabetic foot [PDF]

, 2008
Neuropathy, or the impairment of nerve structures and function, is a common complication in diabetes and affects up to one-third of patients. The most common manifestation is the loss of pain sensation and this can lead to unrecognised trauma injuries ...
Newton, Veronica
core   +4 more sources

Primary care incidence and treatment of four neuropathic pain conditions: A descriptive study, 2002–2005

BMC Family Practice, 2008
Background Between 1992 and 2001 the UK general practice incidence of post-herpetic neuralgia and trigeminal neuralgia declined, whilst the incidence of painful diabetic neuropathy increased. The most common first line treatments were compound analgesics.
Carroll Dawn, Hall Gillian C, McQuay Henry J   +2 more
doaj   +1 more source

High leukotriene B4 serum levels increase risk of painful diabetic neuropathy among type 2 diabetes mellitus patients

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Painful diabetic neuropathy is one of the most common complications of type 2 diabetes mellitus, with approximately 30–50% of people will experience diabetic neuropathy.
Kelvin Yuwanda, I Putu Eka Widyadharma, Dewa Putu Gde Purwa Samatra, I Made Oka Adnyana, Anna Marita Gelgel, I Komang Arimbawa   +5 more
doaj   +1 more source

Metformin Use Is Not Associated With B12 Deficiency or Neuropathy in Patients With Type 2 Diabetes Mellitus in Qatar

Frontiers in Endocrinology, 2018
BackgroundMetformin may lead to B12 deficiency and neuropathy. There are no published data on the prevalence of Metformin-related B12 deficiency and neuropathy in the Arabian Gulf.AimsDetermine whether Metformin intake is associated with B12 deficiency ...
Tarik Elhadd, Tarik Elhadd, Georgios Ponirakis, Zeinab Dabbous, Mashhood Siddique, Subitha Chinnaiyan, Rayaz A. Malik, Rayaz A. Malik   +7 more
doaj   +1 more source

Diagnosis and rational treatment of painful diabetic peripheral neuropathy: an interdisciplinary expert consensus

Сахарный диабет, 2019
Diabetic peripheral neuropathy is a common chronic complication of diabetes mellitus, significantly impairing well-being, quality of life and functioning of patients.
Gagik R. Galstyan, Elena G. Starostina, Nikolay N. Yakhno, Irina V. Gurieva, Maxim V. Churyukanov, Igor A. Strokov, Alla Y. Tokmakova, Mikhail L. Kukushkin, Anatoly I. Martynov, Marina V. Shestakova   +9 more
doaj   +1 more source

Clinical approach to the treatment of painful diabetic neuropathy

Therapeutic Advances in Endocrinology and Metabolism, 2011
Painful neuropathy is a common and often progressive complication of diabetes. Patients frequently report symptoms of tingling, burning, lancinating pain, hyperesthesia, and allodynia.
Alexandra Hovaguimian, Christopher H. Gibbons   +1 more
doaj   +1 more source

Correlation of vitamin D and diabetic peripheral neuropathic pain: A cross-sectional study

Journal of International Medical Research
Objective Although ample evidence exists on the association between vitamin D deficiency and diabetic peripheral neuropathy, only a few studies have distinguished between painful and painless forms.
Caixia Yao, Li Wang, Hongman Zhang, Wenping Yang, Ying Zhong, Wenli Han, Ji Xu, Yan Chen, Ping Wang, Shoucheng Zhang   +9 more
doaj   +1 more source

Pharmacological Modulation of Rate-Dependent Depression of the Spinal H-Reflex Predicts Therapeutic Efficacy against Painful Diabetic Neuropathy

Diagnostics, 2021
Impaired rate-dependent depression (RDD) of the spinal H-reflex occurs in diabetic rodents and a sub-set of patients with painful diabetic neuropathy. RDD is unaffected in animal models of painful neuropathy associated with peripheral pain mechanisms and
Corinne A. Lee-Kubli, XiaJun Zhou, Corinne G. Jolivalt, Nigel A. Calcutt   +3 more
doaj   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source