Results 11 to 20 of about 11,356 (208)
Optimising the Therapeutic Window: A Systematic Review and Network Meta-Analysis of Pregabalin Dosing Strategies for Painful Diabetic Neuropathy. [PDF]
Diabetes Obes MetabABSTRACT Aims Although pregabalin is a first‐line therapy for painful diabetic polyneuropathy (PDPN), its optimal dose–response relationship remains unclear. We conducted a network meta‐analysis to evaluate the efficacy and safety of fixed pregabalin dosages in PDPN patients.
Kwon D +5 more
europepmc +2 more sources
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Alleviation of pain in painful diabetic neuropathy [PDF]
Expert Opinion on Drug Metabolism & Toxicology, 2016 Painful diabetic neuropathy (PDN) is a disabling pain condition. Its pathomechanism remains unknown, but a sensitization and neuronal hyperexcitabilty have been suggested. Only symptomatic pharmacological pain management treatment is currently available.The origin of PDN is enigmatic, and the evidence-based therapeutic guidelines therefore consist only
Tajti János +5 more
openaire +3 more sources
Benefits of vitamin D as an additional therapy in painful diabetic neuropathy: Case report and recent literature review [PDF]
Romanian Journal of Neurology, 2022 The common chronic complication from diabetes mellitus (DM) is painful diabetic neuropathy. The available symptomatic treatment with standard therapy is not sufficient for pain reduction.
Rizaldy Taslim Pinzon, Diana Teresa
doaj +1 more source
Changes in the central nervous system in diabetic neuropathy
Heliyon, 2023 One of the most common chronic complications arising from diabetes is diabetic peripheral neuropathy. Depending on research statistics, approximately half of the people who have diabetes will suffer from diabetic peripheral neuropathy over time, which ...
Yarui Zang +3 more
doaj +1 more source
Frontiers in Endocrinology, 2020 Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg amputation, and neuropathic pain (painful-DPN).
Heng Yang +6 more
doaj +1 more source
Treatment of painful diabetic neuropathy [PDF]
Therapeutic Advances in Chronic Disease, 2014 Painful diabetic neuropathy (PDN) is a debilitating consequence of diabetes that may be present in as many as one in five patients with diabetes. The objective assessment of PDN is difficult, making it challenging to diagnose and assess in both clinical practice and clinical trials.
Javed, Saad +3 more
openaire +2 more sources
EFFECTS OF MLS-LASER ON NEUROPATHIC PAIN IN DIABETIC SENSОMOTOR NEUROPATHY [PDF]
Journal of IMAB, 2023 About 20-50 % of patients with diabetes and about 60 % of those with diabetic neuropathy develop neuropathic pain, which is characterized by tingling, burning, sharp, shooting, or stabbing sensations, and even electric shock-like sensations.
Lili Yosifova +2 more
doaj +1 more source
Asian Journal of Medical Sciences, 2022 Background: Diabetes has reached epidemic proportion in India. The most common complication of Type 2 diabetes mellitus (T2DM) is diabetic polyneuropathy (DPN). Various theories have been proposed to explain development of DPN, among which newer concepts
Debarati Chanda +4 more
doaj +1 more source
Treatment of painful diabetic neuropathy
Consilium Medicum, 2021 Painful diabetic neuropathy is observed in almost half of patients with diabetes mellitus (DM) and is associated with a decrease in the quality of life, emotional disorders, sleep disorders.
Vladimir A. Parfenov +1 more
doaj +1 more source