Results 101 to 110 of about 5,176,832 (349)

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Effect of a fat-free diet and of different dietary fatty acids (palmitate, oleate, and linoleate) on the fatty acid composition of fresh-water fish lipids

Journal of Lipid Research, 1963
When fresh-water fish Pimelodus maculatus were fed a fat-deficient diet, the concentration of linoleic and arachidonic acids in glycerides and phospholipids decreased, and the concentration of palmitic, palmitoleic, oleic, and eicosatrienoic acids ...
R.R. Brenner, D.V. Vazza, M.E. De Tomás
doaj   +1 more source

Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β

PLoS ONE, 2017
Palmitic acid (PA) and other saturated fatty acids are known to stimulate pro-inflammatory responses in human immune cells via Toll-like receptor 4 (TLR4).
Dequina A. Nicholas, Kangling Zhang, C. Hung, Shane L. Glasgow, A. Aruni, J. Unternaehrer, K. Payne, W. Langridge, Marino De León   +8 more
semanticscholar   +1 more source

Guidelines for the Anti‐Obesity Assays of Food Bioactives in Caenorhabditis elegans

AgriFood: Journal of Agricultural Products for Food, EarlyView.
This Guideline uses Caenorhabditis elegans as a model organism to systematically explain and summarize the research strategies and experimental methods for the anti‐obesity effects of food bioactives. ABSTRACT The obesity has become a global public health problem and is closely related to a variety of chronic diseases.
Rui Lu
wiley   +1 more source

Enzymatic Cellulose Palmitate Synthesis Using Immobilized Lipase

Research Journal of Life Science, 2017
Bacterial cellulose can be modified by esterification using palmitic acid and Mucor miehei  lipase  as catalyst. The purpose of this research was to determine the optimum conditions of esterification reaction of cellulose and palmitic acid .
Anna Roosdiana, Diah Mardiana, Ellya Indahyanti, Dyah Ayu Oktavianie   +3 more
doaj   +1 more source

The Hepatotoxicity of Palmitic Acid in Zebrafish Involves the Intestinal Microbiota.

Journal of NutriLife, 2018
Background Palmitic acid (PA) is the main saturated fatty acid naturally occurring in animal fats and vegetable oils. In recent decades, palm oil, an alternative lipid source containing high amounts of PA, has been widely used to replace fish oil in ...
Qianwen Ding, Zhen Zhang, Chao Ran, Suxu He, Yalin Yang, Z. Du, Jinxiong Zhang, Zhigang Zhou   +7 more
semanticscholar   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

Archaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares, Eriola Jakoel, Ron Be’eri, Oded Lipschits, Ronny Neumann, Yuval Gadot   +5 more
wiley   +1 more source

Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression [PDF]

, 2023
Qiang Zhang, Xiaoya Yang, Jinjie Wu, Shubiao Ye, Junli Gong, Wai Ming Cheng, Zhanhao Luo, Jing Yu, Yugeng Liu, Wanyi Zeng, Chen Liu, Zhizhong Xiong, Yuan Chen, Zhen He, Ping Lan   +14 more
openalex   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source