Results 221 to 230 of about 81,377 (299)

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Palmitic acid differently modulates extracellular vesicles and cellular fatty acid composition of SGBS adipocytes without impairing their insulin signaling. [PDF]

Front Endocrinol (Lausanne)
Sergi D, Angelini S, Castaldo F, Beccaria M, Bellinghieri C, Franchina F, Omenetto A, Stifani G, Del Mastro S, Merighi S, Gessi S, Jugdaohsingh R, Cervellati C, Wabitsch M, Neri LM, Bidault G, Vidal-Puig A, Sanz JM, Passaro A.   +18 more
europepmc   +1 more source

Integrative Assessment of Desmostachya bipinnata (L.) Root Extract: Anti‐Inflammatory and Antinociceptive Effects Supported by Molecular Docking and Network Pharmacology

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 841-858, July 2026.
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique, Muhammad Muzammil Nazir, Saima Muzammil, Iqra Farzeen, Shafaq Latif, Asma Ashraf, Jorddy Neves Cruz   +6 more
wiley   +1 more source

HERPUD1 mediates palmitic acid-induced UPR sustaining TNBC aggressiveness and is destabilized by CK2 pharmacological inhibition. [PDF]

Cell Death Dis
Hernández-Torres L, Cavieres VA, Cortés O, Arias-Muñoz E, Cruzat-Arias F, Catalán-Aguilera J, Álvarez-Indo J, Aguilera-Olguín M, Hernández R, Silva-Pavez E, Tapia JC, Cancino J, Lagos CF, Pástor TP, Galarza AJ, Mardones GA, Varas-Godoy M, Villarreal-Cruz N, Villarroel-Espindola F, Saffie I, González A, Barrera MJ, Ehrenfeld P, Burgos PV.   +23 more
europepmc   +1 more source

Phytochemical Composition and Potential Bioactivity With ADMET Analysis of Selected Species From Myrtaceae Family

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 1002-1029, July 2026.
Investigation of four medicinal plants of the family Myrtaceae. ABSTRACT Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options for human healthcare. This study aimed to evaluate the phytochemical composition, antioxidant potential, in vitro anti‐inflammatory, antibacterial and ...
Archana Joshi, Vaishnavi Rawat, Ravendra Kumar, Stefania Garzoli, Anil Kumar Pant, Marcin Stocki, Valery A. Isidorov, Om Prakash, Dharmendra Singh Rawat   +8 more
wiley   +1 more source

Palmitic acid and palmitoylation in cancer: Understanding, insights, and challenges. [PDF]

Innovation (Camb)
Song P, Jiang Q, Wu X, Bu L, Xie W, Wei W, Xing X, Guo J.   +7 more
europepmc   +1 more source

Soybean‐Derived Exosome‐Like Nanovesicles Regulate Lipid Metabolism via Mitochondrial Biogenesis and UCP1/PGC‐1α Mediated Thermogenesis

Food Frontiers, Volume 7, Issue 4, July 2026.
Soybean‐derived exosome‐like nanovesicles suppress lipid accumulation of adipocytes via UCP1/PGC‐1α mediated thermogenesis pathway and boosting mitochondrial function. ABSTRACT Obesity has become an important public health concern in modern society. Plant‐derived exosome‐like nanovesicles are emerging as candidates for obesity intervention.
Zhenzhu Zhu, Luyuan Ni, Mingwei Gao, Qian Yang, Changli Zhang, Qin Liu   +5 more
wiley   +1 more source

Palmitic acid alone or combined with stearic and oleic enhances ruminal fiber degradation and alters microbiome composition. [PDF]

Front Microbiol
Batistel F, Gonzalez O, Sears A, Khan SU, de Souza J.   +4 more
europepmc   +1 more source

Decoding Biothreats With FT‐ICR‐MS: Metabotyping of Bacillus cereus Spores Through Untargeted Metabolomics

Journal of Mass Spectrometry, Volume 61, Issue 7, July 2026.
ABSTRACT Genome sequencing is the gold standard for microbial identification. However, it fails to distinguish closely related species with overlapping genetic features. This is the case of Bacillus cereus and Bacillus cytotoxicus, two members of the B. cereus group with distinct pathogenic profiles. While B. cereus, a well‐known opportunistic pathogen
Maria Inês Romão, Inês Gomes, Wilson Antunes, Petr Novak, Marta Sousa Silva, Carlos Cordeiro   +5 more
wiley   +1 more source

High Ratio of Dietary Palmitic Acid to DHA + EPA Induces Glucose Metabolic Disorder Through Endocrine and Transcriptional Regulation in Large Yellow Croaker (Larimichthys crocea). [PDF]

Metabolites
Wang Q, Ge H, Gu Z, Chen H, Mu H, Mai K, Zhang W.   +6 more
europepmc   +1 more source