Results 231 to 240 of about 81,377 (299)

Development and Application of Prime Editors for the Induction of Site‐Specific, Heritable Edits in Soybean [Glycine max (L.) Merr.]

Plant Biotechnology Journal, EarlyView.
Nirmal Khadka, Hien Thuy Bui, Ajay Gupta, Steve A. Whitham, Bing Yang   +4 more
wiley   +1 more source

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, Volume 36, Issue 4, July 2026.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source

Neural-Inflammation Mechanism of Spinal Palmitic Acid Promoting Atopic Dermatitis in Mice. [PDF]

J Inflamm Res
Yang J, Xue X, Yang Z, Hao F, Chen B.
europepmc   +1 more source

Drought and Herbivory Have Selective Transgenerational Effects on Soybean Eco‐Physiology, Defence and Fitness

Plant, Cell &Environment, Volume 49, Issue 7, Page 4352-4371, July 2026.
ABSTRACT Soybeans, one of the most important legumes, face multiple stresses including drought and herbivory. But the potential transfer of the interactive effects of these stressors onto the transgenerational plants has not been understood. We hypothesised that progeny from stressed parents will have enhanced ecophysiology and defence traits through ...
Manish Gautam, Rupesh Kariyat
wiley   +1 more source

Palmitic acid aggravates atopic dermatitis by regulating SGK1/NEDD4L-involved cutaneous neuroimmune inflammation through driving TRPV1 and MRGPRB2 S-palmitoylation. [PDF]

Inflamm Res
Chen B, Yang J, Song T, Wu W, Hao F, Yang Z.   +5 more
europepmc   +1 more source

Targeting Fatty Acid Synthase With Berberine Promotes IL‐10 Production in Macrophages and Prevents Relapse in a Murine Colitis Model

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Berberine enhances IL‐10 production in macrophages via FASN‐dependent mechanisms, thereby promoting epithelial repair and preventing colitis relapse. Created with BioRender.com. ABSTRACT Inflammatory bowel disease (IBD) is a chronic inflammatory disorder characterized by alternating periods of remission and relapse.
Shusaku Hayashi, Yudai Ogawa, Nonoka Wakabayashi, Koga Tokuyama, Makito Oku, Takeshi Yamamoto, Shinichi Kato, Asma Nusrat, Makoto Kadowaki   +8 more
wiley   +1 more source

Hesperetin Protects from Palmitic-Acid-Induced Lipotoxicity through the Inhibition of Glutaminolysis, mTORC1 Signaling, and Limited Apoptosis. [PDF]

J Agric Food Chem
Li W, Cai Z, Schindler F, Brenner M, Winter C, Stiller B, Heffeter P, Weckwerth W.   +7 more
europepmc   +1 more source

Cannabigerol Alleviates Obesity‐Induced Mitochondrial Dysfunction by Cardiolipin Fatty Acid Remodeling

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Graphical overview of the effects of the high‐fat, high‐sucrose (HFHS) diet regime and 2‐week cannabigerol (CBG) treatment on the intramuscular long‐chain fatty acids (LCFAs) trafficking and lipid metabolism, with subsequent implications for mitochondrial cardiolipin (CL) composition in the red gastrocnemius muscle.
Patrycja Bielawiec, Karolina Konstantynowicz‐Nowicka, Adrian Chabowski, Ewa Harasim‐Symbor   +3 more
wiley   +1 more source

Protective role of oleic acid against palmitic acid-induced pancreatic fibrosis. [PDF]

J Transl Med
Frendi S, Chassac A, Veron K, Raffenne J, Nicolle R, Albuquerque M, Paradis V, Couvelard A, Cros J, Rebours V.   +9 more
europepmc   +1 more source

miRNA Sensor HuR Compartmentalizes Ago2‐Uncoupled miRNAs to Lipid Droplets to Buffer miRNA Activity in Mammalian Cells

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
This study revealed a dose‐dependent miRNA buffering mechanism involving extracellular export and storage of miRNA on lipid droplets. The protein HuR facilitates miRNA buffering by dissociating miRNAs from Ago2 and promoting miRNA accumulation on lipid droplets or its extracellular export, depending on cellular requirements.
Sreemoyee Chakraborty, Diptankar Bandyopadhyay, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +3 more
wiley   +1 more source