Results 241 to 250 of about 81,377 (299)

Protective effects of α-ketoglutaric acid on palmitic acid-induced deterioration in sheep endometrial epithelial cells via ferroptosis inhibition. [PDF]

Front Vet Sci
Bai Z, Fang Q, Li S, Jia M, Zhang R, Wang C, Wu Z, Liu G, Liu Y.   +8 more
europepmc   +1 more source

Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion

Chemistry – A European Journal, Volume 32, Issue 22, 9 June 2026.
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere, Xavier Bantreil, Frédéric Lamaty   +2 more
wiley   +1 more source

Palmitic Acid Accumulation Activates Fibroblasts and Promotes Matrix Stiffness in Colorectal Cancer. [PDF]

Cancer Res
Deng S, Wang J, Zou F, Cheng D, Chen M, Gu J, Shi J, Yang J, Xue Y, Jiang Z, Qin L, Mao F, Chang X, Nie X, Liu L, Cao Y, Cai K.   +16 more
europepmc   +1 more source

Emerging Trends in Organic Photoreactions Utilizing Disulfides

European Journal of Organic Chemistry, Volume 29, Issue 21, 4 June 2026.
Disulfides are versatile, nontoxic alternatives to metal photocatalysts. This review explores their role as photoactivated thiyl‐radical precursors and bifunctional catalysts (HAT/electron shuttling) in diverse transformations. Strategies for electronic tuning and development into recyclable heterogeneous materials are highlighted for sustainable ...
Sunil Kumar, Bolormaa Bayarkhuu, Hong Y. Cho, Jeehye Byun   +3 more
wiley   +1 more source

Palmitic Acid Induces Dynamic Time-Dependent Alterations in HDACs, Neuronal Chromatin Acetylation, and Gene Expression. [PDF]

Neurochem Res
Rueda-Díaz SS, Soto-Santarriaga IF, Torres-Arciga K, García-Cruz VM, González-Barrios R, Flores-León M, Arias C.   +6 more
europepmc   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

High-fat diet increases circulating palmitic acid produced by gut Bacteroides thetaiotaomicron to promote thrombosis. [PDF]

Cell Rep Med
Huang X, Tang X, He Q, Tadese DA, Cao K, Gao J, Xu Q, Cheng R, Lu Q, Chen Y, Yang M, Du Y, Mwangi J, Ni H, Lai R.   +14 more
europepmc   +1 more source

Oleic acid restores the impaired antitumor immunity of γδ-T cells induced by palmitic acid. [PDF]

Signal Transduct Target Ther
Zhang Y, Xiang Z, Xu Y, Cheung LS, Wang X, Wang M, Wong HHW, Zhu Z, Zhang W, Gao Y, Luo X, Cheuk YC, Zhou Y, Zha X, Chen Y, Li M, Luo F, Chu Y, Lau YL, Liu Y, Tu W.   +20 more
europepmc   +1 more source

Maternal palmitic acid overload establishes a SETD1A-dependent epigenetic memory that programs offspring susceptibility to metabolic liver disease

Benitah S, Bigas C, Martín J, Kimura M, Dilme J, Radio S, Hensgens A, Liesa M, Reisz J, Dzieciatkowska M, D'Alessandro A, Porteiro B, Nogueiras R, Zhao Z, Shilatifard A, Takebe T, Majem B.   +16 more
europepmc   +1 more source

Danshensu Attenuates Palmitic Acid-Induced Activation of Hepatic Stellate Cells by Regulating Pyroptosis. [PDF]

Int J Med Sci
Tseng HF, Chao HN, Lin CH, Kuo CY.
europepmc   +1 more source