Results 251 to 260 of about 119,296 (338)

Lipid regulation of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis by its membrane‐domain receptor

The FEBS Journal, EarlyView.
The adenylyl cyclase (AC) Rv1625c from M. tuberculosis is a monomeric progenitor of the nine pseudoheterodimeric mammalian AC isoforms. The hexahelical membrane anchor of Rv1625c serves as an inhibitory receptor for fatty acids, particularly oleic acid. One ligand binds into each monomer of the active Rv1625c dimer.
Anita Charlotte Friderun Schultz, Marius Landau, Andrei N. Lupas, Joachim Erdmann Schultz   +3 more
wiley   +1 more source

Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice. [PDF]

Nat Commun
Yin W, Xu H, Bai Z, Wu Y, Zhang Y, Liu R, Wang Z, Zhang B, Shen J, Zhang H, Chen X, Ma D, Shi X, Yan L, Zhang C, Jiang H, Chen K, Guo D, Niu W, Yin H, Zhang WJ, Luo C, Xie X.   +22 more
europepmc   +1 more source

Compositional and Metabolomic Shifts of the Gut Microbiome in Alcohol‐Related Liver Disease

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Alcohol‐related liver disease (ALD) is a major global health concern characterized by steatosis and liver inflammation due to chronic alcohol consumption. Emerging evidence suggests that ALD is not solely a liver pathology but also involves dysfunction of the gut‐liver axis, where alterations in the gut microbiota play a significant role ...
Cheng‐Hao Kuo, Emad El‐Omar, Cheng‐Yen Kao, Jaw‐Town Lin, Chun‐Ying Wu   +4 more
wiley   +1 more source

Unveiling the Mechanism of Action of Palmitic Acid, a Human Topoisomerase 1B Inhibitor from the Antarctic Sponge <i>Artemisina plumosa</i>. [PDF]

Int J Mol Sci
Ottaviani A, Pietrafesa D, Soren BC, Dasari JB, Olsen SSH, Messina B, Demofonti F, Chicarella G, Agama K, Pommier Y, Morozzo Della Rocca B, Iacovelli F, Romeo A, Falconi M, Baker BJ, Fiorani P.   +15 more
europepmc   +1 more source

In rat hepatocytes, myristic acid occurs through lipogenesis, palmitic acid shortening and lauric acid elongation

, 2007
Vincent Rioux, Daniel Catheline, Philippe Legrand   +2 more
openalex   +1 more source

Almost billfish: convergent longirostry, micro‐dentition, and possible glandular sinuses in a large teleost fish from the Upper Cretaceous of Northern Italy

Journal of Anatomy, EarlyView.
A fossil rostrum fragment of a large teleost fish from the Upper Cretaceous of Northern Italy reveals remarkable anatomical convergences with Cenozoic and Recent billfishes (marlins, swordfishes, and akin). The extinct group Plethodidae independently acquired a long snout, micro‐teeth, and oil‐gland sinuses well before the evolution of true billfishes.
Giovanni Serafini, Jürgen Kriwet, Tommaso Toldo, Eliana Fornaciari, Jacopo Amalfitano, Giorgio Carnevale   +5 more
wiley   +1 more source

Lipotoxicity of palmitic acid is associated with DGAT1 downregulation and abolished by PPARα activation in liver cells. [PDF]

J Lipid Res
Moliterni C, Vari F, Schifano E, Tacconi S, Stanca E, Friuli M, Longo S, Conte M, Salvioli S, Gnocchi D, Mazzocca A, Uccelletti D, Vergara D, Dini L, Giudetti AM.   +14 more
europepmc   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

Subcellular expression of CYP2E1 in HepG2 cells impacts response to free oleic and palmitic acid. [PDF]

Curr Res Toxicol
Killingsworth ZK, Misare KR, Ryan AS, Ampolini EA, Mendenhall TT, Engevik MA, Hartman JH.   +6 more
europepmc   +1 more source

Effects of Fasting and Pyruvate on Palmitic Acid Metabolism

Journal of Biological Chemistry, 1953
Ethel J. Bowie, Jacqueline C. Bates, Robert P. Geyer   +2 more
openaire   +3 more sources