Results 1 to 10 of about 26,438 (282)

Convergent Synthesis of PAMAM-like Dendrimers from Azide-functionalized PAMAM Dendrons [PDF]

Bulletin of the Korean Chemical Society, 2006
The convergent synthesis of symmetric PAMAM-like dendrimers from azide-functionalized poly(amido- amine) (PAMAM) dendrons and two different multi-alkynes was investigated. The stitching method was based on the click chemistry protocol, i.e., the copper-catalyzed cycloaddition reaction between an alkyne and an azide.
Jae Wook Lee, Jung Hwan Kim, Byung-Ku Kim, Ji Hyeon Kim, Won Suk Shin, Sung‐Ho Jin, Myunghak Kim   +6 more
openalex   +4 more sources

Structure of poly(propyl ether imine) (PETIM) dendrimer from fully atomistic molecular Dynamics Simulation and by Small Angle X-ray scattering [PDF]

JCP, 124, 204719 (2006), 2006
We study the structure of carboxylic acid terminated neutral poly (propyl ether imine) (PETIM) dendrimer from generation 1 through 6 (G1-G6) in a good solvent (water) by fully atomistic molecular dynamics (MD) simulations. We determine as a function of generation such structural properties as: radius of gyration, shape tensor, asphericity, fractal ...
A. K. Sood, Adronov A., Chandan Jana, G. Jayamurugan, Hearshaw M. A., N. Jayaraman, Prabal K. Maiti, Rajesh Ganapathy, Rapaport D. C.   +8 more
arxiv   +5 more sources

Structure of Carbon Nanotube-dendrimer composite [PDF]

, 2012
Using all atomistic molecular dynamics (MD) simulations we report the microscopic picture of the nanotube-dendrimer complex for PAMAM dendrimer of generation 2 to 4 and carbon nanotube of chirality (6,5). We find compact wrapping conformations of dendrimer onto the nanotube surface for all the three generations of PAMAM dendrimer.
Maiti, Prabal K, Pramanik, Debabrata, Sood, A. K., Vasumathi, V.   +3 more
arxiv   +3 more sources

Structure of DNA-Functionalized Dendrimer Nanoparticles [PDF]

Soft Matter, 2012, 8, 1893-1900, 2012
Atomistic molecular dynamics simulations have been carried out to reveal the characteristic features of ethylenediamine (EDA) cored protonated poly amido amine (PAMAM) dendrimers of generation 3 (G3) and 4 (G4) that are functionalized with single stranded DNAs (ssDNAs).
Aldaye, Alivisatos, Bao, Berendsen, Blab, Bliznyuk, Carbone, Choi, Choi, Condon, Dai, Dai, Duan, Esfand, Feldkamp, Gurtovenko, Hainfeld, Hill, Hsu, Huang, Hurst, Jain, Jain, Jorgensen, Kalogianni, Karatasos, Ke, Klos, Lara, Largo, Lee, Lee, Lee, Lee, Li, Liu, Lu, Lyulin, Macfarlane, Maiti, Maiti, Maiti, Maiti, Maiti, Mattaparthi Venkata Satish Kumar, Mayo, Mijovic, Mirkin, Mizutani, Nandy, Niemeyer, Niemeyer, Nykypanchuk, Paciotti, Padovan-Merhar, Park, Park, Pearlman, Prabal K Maiti, Rosi, Rosi, Ryckaert, Seeman, Sosinsky, Starr, Stechemesser, Storhoff, Suek, Sun, Thankappan, Tomalia, Tomalia, Tomalia, Tomalia, Tomalia, Uppuluri, Vasumathi, Xiong, Zhao   +78 more
arxiv   +3 more sources

Amine Functionalization of Cholecyst-Derived Extracellular Matrix with Generation 1 PAMAM Dendrimer [PDF]

, 2008
This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Biomacromolecules, copyright © American Chemical Society after peer review.
Jeffrey C. Y. Chan, Krishna Burugapalli, Hemantkumar Naik, John L. Kelly, Abhay Pandit   +4 more
openalex   +3 more sources

Condensation transition in DNA-polyaminoamide dendrimer fibers studied using optical tweezers [PDF]

Phys. Rev. Lett. 96, 118301 (2006), 2006
When mixed together, DNA and polyaminoamide (PAMAM) dendrimers form fibers that condense into a compact structure. We use optical tweezers to pull condensed fibers and investigate the decondensation transition by measuring force-extension curves (FECs).
C. Bustamante, C. G. Baumann, F. Ritort, G. I. Bell, J. F. Marko, S. B. Smith, S. Mihardja   +6 more
arxiv   +5 more sources

Acetylation of PAMAM dendrimers for cellular delivery of siRNA [PDF]

BMC Biotechnology, 2009
AbstractBackgroundThe advancement of gene silencing via RNA interference is limited by the lack of effective short interfering RNA (siRNA) delivery vectors. Rational design of polymeric carriers has been complicated by the fact that most chemical modifications affect multiple aspects of the delivery process.
Carolyn L. Waite, Sarah M. Sparks, Kathryn E. Uhrich, Charles M. Roth   +3 more
openalex   +8 more sources

PAMAM dendrimer - cell membrane interactions.

Advances in Colloid and Interface Science, 2018
PAMAM dendrimers have been conjectured for a wide range of biomedical applications due to their tuneable physicochemical properties. However, their application has been hindered by uncertainties in their cytotoxicity, which is influenced by dendrimer generation (i.e.
Laura J. Fox, R. Richardson, W. Briscoe
semanticscholar   +6 more sources

Morphological Observation of Interaction between PAMAM Dendrimer Modified SWCNT and Pancreatic Cancer Cells [PDF]

Nano Biomedicine and Engineering, 2010
With the aim of observing morphological changes of pancreatic cancer cells transfected by PAMAM dendrimer modified single walled carbon nanotubes(SWCNT-PAMAM complexes), the SWCNT-PAMAM complexes were prepared and characterized by atom force microscopy ...
Dongfeng Chen, Xubo Wu, Jiaxiang Wang, Baosan Han, Ping Zhu, Chenghong Peng   +5 more
doaj   +2 more sources

Molecular Dynamics Study of Charged Dendrimers in Salt-Free Solution: Effect of Counterions [PDF]

, 2005
Polyamidoamine (PAMAM) dendrimers, being protonated under physiological conditions, represent a promising class of nonviral, nano-sized vectors for drug and gene delivery. We performed extensive molecular dynamics simulations of a generic model dendrimer in a salt-free solution with dendrimer's terminal beads positively charged.
Andrey A. Gurtovenko, Galperin D. E., Ilpo Vattulainen, Mikko Karttunen, Sergey V. Lyulin   +4 more
arxiv   +6 more sources