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A Review on Increasing the Targeting of PAMAM as Carriers in Glioma Therapy
Glioma is an invasive brain cancer, and it is difficult to achieve desired therapeutic effects due to the high postoperative recurrence rate and limited efficacy of drug therapy hindered by the biological barrier of brain tissue.
Xingyue Li +4 more
doaj +2 more sources
Recent Advances in Preclinical Research Using PAMAM Dendrimers for Cancer Gene Therapy [PDF]
Carriers of genetic material are divided into vectors of viral and non-viral origin. Viral carriers are already successfully used in experimental gene therapies, but despite advantages such as their high transfection efficiency and the wide knowledge of ...
Piotr Tarach, A. Janaszewska
semanticscholar +2 more sources
The Effect of PAMAM Dendrimers on the Antibacterial Activity of Antibiotics with Different Water Solubility [PDF]
Erythromycin (EM) and tobramycin (TOB) are well-known and widely used antibiotics, belonging to different therapeutic groups: macrolide and aminoglycoside, respectively.
Elzbieta Anna Tryniszewska +4 more
doaj +2 more sources
Glioblastoma (GB) is a grade IV astrocytoma that maintains a poor prognosis with respect to current treatment options. Despite major advancements in the fields of surgery and chemoradiotherapy over the last few decades, the life expectancy for someone ...
M. Fana +4 more
semanticscholar +3 more sources
Polyamidoamine (PAMAM) dendrimers are efficient drug carriers. The presence of a physiological pathway for nasal brain transport provides a potential path for direct brain-targeted delivery of dendrimer nanocomposites. In this study, we synthesized PAMAM
Huichao Xie +9 more
doaj +2 more sources
PAMAM-Lys, a novel vaccine delivery vector, enhances the protective effects of the SjC23 DNA vaccine against Schistosoma japonicum infection. [PDF]
BACKGROUND: Schistosomiasis japonica remains a major public-health concern in China. Praziquantel-based chemotherapy effectively reduces both infections and intensity; however, it can not prevent re-infection.
Xiaoting Wang +10 more
doaj +3 more sources
PAMAM dendrimer - cell membrane interactions.
Laura J. Fox, R. Richardson, W. Briscoe
semanticscholar +3 more sources
In this work, we prepared a novel electrochemical sensor for the detection of tramadol based on a UiO-66-NH2 metal–organic framework (UiO-66-NH2 MOF)/third-generation poly(amidoamine) dendrimer (G3-PAMAM dendrimer) nanocomposite drop-cast onto a glassy ...
Fariba Garkani Nejad +2 more
semanticscholar +1 more source
In this paper, a simple strategy was proposed for the analysis of catechol by a carbon paste electrode (CPE) modified with graphene oxide–third generation of poly(amidoamine) dendrimer (GO/G3–PAMAM) nanocomposite and ionic liquid (IL).
Fariba Garkani Nejad +2 more
semanticscholar +1 more source
Fluorescent nanosized PAMAM dendrimers: One-step formation of a bright blue fluorophore on terminal groups and its optical properties [PDF]
Background and Objectives: Polyamidoamine dendrimers (PAMAM) are nanoscale monodisperse compounds with a multifunctional terminal surface. Structural features of PAMAM, such as a nanosize of high homogeneity, highly developed terminal surface and ...
Mordovina, Ekaterina Alekseevna +7 more
doaj +1 more source

