Results 1 to 10 of about 9,478 (168)

A Review on Increasing the Targeting of PAMAM as Carriers in Glioma Therapy

open access: yesBiomedicines, 2022
Glioma is an invasive brain cancer, and it is difficult to achieve desired therapeutic effects due to the high postoperative recurrence rate and limited efficacy of drug therapy hindered by the biological barrier of brain tissue.
Xingyue Li   +4 more
doaj   +2 more sources

Recent Advances in Preclinical Research Using PAMAM Dendrimers for Cancer Gene Therapy [PDF]

open access: goldInternational Journal of Molecular Sciences, 2021
Carriers of genetic material are divided into vectors of viral and non-viral origin. Viral carriers are already successfully used in experimental gene therapies, but despite advantages such as their high transfection efficiency and the wide knowledge of ...
Piotr Tarach, A. Janaszewska
semanticscholar   +2 more sources

The Effect of PAMAM Dendrimers on the Antibacterial Activity of Antibiotics with Different Water Solubility [PDF]

open access: goldMolecules, 2013
Erythromycin (EM) and tobramycin (TOB) are well-known and widely used antibiotics, belonging to different therapeutic groups: macrolide and aminoglycoside, respectively.
Elzbieta Anna Tryniszewska   +4 more
doaj   +2 more sources

PAMAM Dendrimer Nanomolecules Utilized as Drug Delivery Systems for Potential Treatment of Glioblastoma: A Systematic Review

open access: greenInternational Journal of Nanomedicine, 2020
Glioblastoma (GB) is a grade IV astrocytoma that maintains a poor prognosis with respect to current treatment options. Despite major advancements in the fields of surgery and chemoradiotherapy over the last few decades, the life expectancy for someone ...
M. Fana   +4 more
semanticscholar   +3 more sources

An Available Strategy for Nasal Brain Transport of Nanocomposite Based on PAMAM Dendrimers via In Situ Gel

open access: yesNanomaterials, 2019
Polyamidoamine (PAMAM) dendrimers are efficient drug carriers. The presence of a physiological pathway for nasal brain transport provides a potential path for direct brain-targeted delivery of dendrimer nanocomposites. In this study, we synthesized PAMAM
Huichao Xie   +9 more
doaj   +2 more sources

PAMAM-Lys, a novel vaccine delivery vector, enhances the protective effects of the SjC23 DNA vaccine against Schistosoma japonicum infection. [PDF]

open access: goldPLoS ONE, 2014
BACKGROUND: Schistosomiasis japonica remains a major public-health concern in China. Praziquantel-based chemotherapy effectively reduces both infections and intensity; however, it can not prevent re-infection.
Xiaoting Wang   +10 more
doaj   +3 more sources

PAMAM dendrimer - cell membrane interactions.

open access: hybridAdvances in Colloid and Interface Science, 2018
Laura J. Fox, R. Richardson, W. Briscoe
semanticscholar   +3 more sources

A UiO-66-NH2 MOF/PAMAM Dendrimer Nanocomposite for Electrochemical Detection of Tramadol in the Presence of Acetaminophen in Pharmaceutical Formulations

open access: yesBiosensors, 2023
In this work, we prepared a novel electrochemical sensor for the detection of tramadol based on a UiO-66-NH2 metal–organic framework (UiO-66-NH2 MOF)/third-generation poly(amidoamine) dendrimer (G3-PAMAM dendrimer) nanocomposite drop-cast onto a glassy ...
Fariba Garkani Nejad   +2 more
semanticscholar   +1 more source

Graphene Oxide–PAMAM Nanocomposite and Ionic Liquid Modified Carbon Paste Electrode: An Efficient Electrochemical Sensor for Simultaneous Determination of Catechol and Resorcinol

open access: yesDiagnostics, 2023
In this paper, a simple strategy was proposed for the analysis of catechol by a carbon paste electrode (CPE) modified with graphene oxide–third generation of poly(amidoamine) dendrimer (GO/G3–PAMAM) nanocomposite and ionic liquid (IL).
Fariba Garkani Nejad   +2 more
semanticscholar   +1 more source

Fluorescent nanosized PAMAM dendrimers: One-step formation of a bright blue fluorophore on terminal groups and its optical properties [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Физика, 2023
Background and Objectives: Polyamidoamine dendrimers (PAMAM) are nanoscale monodisperse compounds with a multifunctional terminal surface. Structural features of PAMAM, such as a nanosize of high homogeneity, highly developed terminal surface and ...
Mordovina, Ekaterina Alekseevna   +7 more
doaj   +1 more source

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