Results 1 to 10 of about 7,634 (170)

Fluorescent nanosized PAMAM dendrimers: One-step formation of a bright blue fluorophore on terminal groups and its optical properties [PDF]

Известия Саратовского университета. Новая серия: Физика, 2023
Background and Objectives: Polyamidoamine dendrimers (PAMAM) are nanoscale monodisperse compounds with a multifunctional terminal surface. Structural features of PAMAM, such as a nanosize of high homogeneity, highly developed terminal surface and ...
Mordovina, Ekaterina Alekseevna, Berdenkova , Victoria Alexandrovna, Bakal, Artem Alekseev, Tsyupka, Daria Vladislavovna, Kokorina, Alina A., Podkolodnaya, Yuliya A., Goryacheva, Olga A., Goryacheva, Irina Yurievna   +7 more
doaj   +1 more source

Second-Generation Polyamidoamine Dendrimer Conjugated with Oligopeptides Can Enhance Plasmid DNA Delivery In Vitro

Molecules, 2023
Poly(amidoamine) (PAMAM) dendrimers have attracted considerable attention in the field of gene therapy due to their flexibility in introducing different functional moieties and reduced toxicity at low generations.
Seongyeon Kim, Le Thi Thuy, Jeil Lee, Joon Sig Choi   +3 more
doaj   +1 more source

Effects of the surface charge of polyamidoamine dendrimers on cellular exocytosis and the exocytosis mechanism in multidrug-resistant breast cancer cells

Journal of Nanobiotechnology, 2021
Background Polyamidoamine (PAMAM) dendrimer applications have extended from tumor cells to multidrug-resistant tumor cells. However, their transportation in multidrug-resistant tumor cells remains unclear.
Jie Zhang, Mingjuan Li, Mingyue Wang, Hang Xu, Zhuoxiang Wang, Yue Li, Baoyue Ding, Jianqing Gao   +7 more
doaj   +1 more source

Multivalent Lactose–Ferrocene Conjugates Based on Poly (Amido Amine) Dendrimers and Gold Nanoparticles as Electrochemical Probes for Sensing Galectin-3

Nanomaterials, 2020
Galectin-3 is considered a cancer biomarker and bioindicator of fibrosis and cardiac remodeling and, therefore, it is desirable to develop convenient methods for its detection.
Manuel C. Martos-Maldonado, Indalecio Quesada-Soriano, Luis García-Fuentes, Antonio Vargas-Berenguel   +3 more
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Diagnostic and therapeutic applications of smart nanocomposite dendrimers

Frontiers in Bioscience-Landmark, 2020
Dendrimers are three dimensional, multifunctional polymeric structures which are composed of a core and branches emanating from these structures, resembling a tree.
Vinay Kumar, Rakesh K. Sahoo, Trambak Basak, Tanjina Yasmin, Umesh Gupta, Amit K. Goyal   +5 more
doaj   +1 more source

β-Cyclodextrin and Oligoarginine Peptide-Based Dendrimer-Entrapped Gold Nanoparticles for Improving Drug Delivery to the Inner Ear

Frontiers in Bioengineering and Biotechnology, 2022
Here, we developed a safe and highly effective nanocarrier using β-cyclodextrin (β-CD) and oligoarginine peptide (Arg8)-modified dendrimer-entrapped gold nanoparticles (Au@CD-PAMAM-Arg8), with a diameter of 5 nm, for improved delivery of dexamethasone ...
Jia Luo, XueXin Lin, LiLing Li, JingQian Tan, Peng Li   +4 more
doaj   +1 more source

A Review on Increasing the Targeting of PAMAM as Carriers in Glioma Therapy

Biomedicines, 2022
Glioma is an invasive brain cancer, and it is difficult to achieve desired therapeutic effects due to the high postoperative recurrence rate and limited efficacy of drug therapy hindered by the biological barrier of brain tissue.
Xingyue Li, Wenjing Ta, Ruochen Hua, Jihong Song, Wen Lu   +4 more
doaj   +1 more source

The inhibitory effect of carboxyl-terminated polyamidoamine dendrimers on dentine host-derived matrix metalloproteinases in vitro in an etch-and-rinse adhesive system [PDF]

Royal Society Open Science, 2019
The biomimetic remineralization of collagen fibrils has increased interest in restoring the demineralized dentine generated by dental caries. Carboxyl-terminated polyamidoamine dendrimers (PAMAM-COOH), hyperbranched polymeric macromolecules, can act as ...
Qian Wu, Tiantian Shan, Manduo Zhao, Sui Mai, Lisha Gu   +4 more
doaj   +1 more source

Polyamidoamide Dendrimers and Cross-Linking Agents for Stabilized Bioenzymatic Resistant Metal-Free Bovine Collagen

Molecules, 2019
The work reports the use of polyamidoamine dendrimers (PAMAM) and a cross-linking agent, 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide/N-hydroxysuccinimide (EDC/NHS) or 4-(4,6-dimethoxy[1,3,5]triazin-2-yl)-4-methyl-morpholinium chloride (DMTMM), for the
Valentina Beghetto, Vanessa Gatto, Silvia Conca, Noemi Bardella, Alberto Scrivanti   +4 more
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Temperature-Responsive Molecular Assemblies Using Oligo(Ethylene Glycol)-Attached Polyamidoamine Dendron Lipids and their Functions as Drug Carriers

Journal of Functional Biomaterials, 2020
Temperature-responsive nanocarrier systems using external stimuli are one of the most widely investigated stimuli-responsive strategies because heat is easy and safe to use for hyperthermia and controlled drug delivery.
Takuya Hashimoto, Yuji Hirai, Eiji Yuba, Atsushi Harada, Kenji Kono   +4 more
doaj   +1 more source