Results 131 to 140 of about 26,467 (310)

Label-Free Fluorescent Poly(amidoamine) Dendrimer for Traceable and Controlled Drug Delivery [PDF]

open access: yes, 2019
Poly(amidoamine) dendrimer (PAMAM) is well-known for its high efficiency as a drug delivery vehicle. However, the intrinsic cytotoxicity and lack of a detectable signal to facilitate tracking have impeded its practical applications.
Chen, Xianfeng   +13 more
core   +2 more sources

Mass spectrometry of dendrimers

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Mass spectrometry (MS) has become an essential technique to characterize dendrimers as it proved efficient at tackling analytical challenges raised by their peculiar onion‐like structure. Owing to their chemical diversity, this review covers benefits of MS methods as a function of dendrimer classes, discussing advantages and limitations of ...
McKenna J. Redding   +2 more
wiley   +1 more source

The Effect of Absorption-Enhancement and the Mechanism of the PAMAM Dendrimer on Poorly Absorbable Drugs

open access: yesMolecules, 2018
The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the mechanism of PAMAM dendrimers with generation 0 to generation 3 (G0–G3) and concentrations (0 ...
Juan Lu   +9 more
doaj   +1 more source

Detection of dengue using PAMAM dendrimer integrated tapered optical fiber sensor

open access: yesScientific Reports, 2019
The exponential escalation of dengue cases has indeed become a global health crisis. This work elaborates on the development of a biofunctionalized tapered optical fiber (TOF) based sensor with the integration of polyamidoamine (PAMAM) dendrimer for the ...
Y. Mustapha Kamil   +6 more
semanticscholar   +1 more source

Predictive Modeling of 6‐Fluoro‐3‐Hydroxy‐2‐Pyrazine Carboxamide Drug Delivery Efficacy in Pegylated Bionanocomposite Through First Principles Simulation

open access: yesNano Select, EarlyView.
Schematic representation of a PEGylated bionanocomposite facilitating the targeted delivery of Favipiravir for enhanced antiviral action against COVID. ABSTRACT This research investigates the drug delivery efficacy for 6‐fluoro‐3‐hydroxy‐2‐pyrazinecarboxamide (favipiravir) in PEGylated bionanocomposites using a predictive modeling approach.
Oluwasegun Chijioke Adekoya   +4 more
wiley   +1 more source

On-Demand Bioadhesive Dendrimers with Reduced Cytotoxicity

open access: yesMolecules, 2018
Tissue adhesives based on polyamidoamine (PAMAM) dendrimer, grafted with UV-sensitive aryldiazirine (PAMAM-g-diazirine) are promising new candidates for light active adhesion on soft tissues.
Feng Gao   +5 more
doaj   +1 more source

Study of Adsorption Mechanism of Congo Red on Graphene Oxide/PAMAM Nanocomposite

open access: yesMaterials, 2018
Graphene oxide/poly(amidoamine) (GO/PAMAM) nanocomposite adsorbed high quantities of congo red (CR) anionic dye in 0.1 M NaCl solution, with the maximum adsorption capacity of 198 mg·g−1. The kinetics and thermodynamics of adsorption were investigated to
M. Rafi, B. Samiey, Chil-Hung Cheng
semanticscholar   +1 more source

Effect of chromophore type on efficiency of reactive dye removal using polyamidoamine dendrimer

open access: yesColoration Technology, EarlyView.
Abstract In this study, by selecting a sample of dyes from a wide variety of chromophores used in the production of reactive dyes (monoazo, bisazo, metal azo, phthalocyanine, anthraquinone, copper formazan and triphendioxazine), the colour removal performance of polyamidoamine (PAMAM) dendrimer in reactive dyes was statistically evaluated depending on ...
Riza Atav   +5 more
wiley   +1 more source

Investigation of Dendriplexes by Ion Mobility-Mass Spectrometry

open access: yesMolecules, 2014
Highly branched polyamidoamine (PAMAM) dendrimers presenting biological activities have been envisaged as non-viral gene delivery vectors. They are known to associate with nucleic acid (DNA) in non-covalent complexes via electrostatic interactions ...
Emma-Dune Leriche   +6 more
doaj   +1 more source

Molecular modelling of dendrimers for nanoscale applications [PDF]

open access: yes, 2000
Dendrimers are well defined, highly branched macromolecules that radiate from a central core and are synthesized through a stepwise, repetitive reaction sequence that guarantees complete shells for each generation, leading to polymers that are ...
Breen, Nicholas   +4 more
core  

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