G4.5 Pamam Dendrimer-Risperidone: Biodistribution and Behavioral Changes in In Vivo Model [PDF]
Dendritic polymers are considered as emerging and outstanding carriers as modern medicinal systems due to their derivatisable branched architecture and possibility to modify them in numerous ways.
Alonso, Silvia del Valle+6 more
core +2 more sources
PAMAM-Lys, a novel vaccine delivery vector, enhances the protective effects of the SjC23 DNA vaccine against Schistosoma japonicum infection. [PDF]
BACKGROUND: Schistosomiasis japonica remains a major public-health concern in China. Praziquantel-based chemotherapy effectively reduces both infections and intensity; however, it can not prevent re-infection.
Xiaoting Wang+10 more
doaj +1 more source
Intrinsic Blue Fluorescence of 2.0G PAMAM-DCM Polymer Dots and Its Applications for Fe3+ Sensing
A typical and environment-friendly fluorescent polyamine-amine (PAMAM) features good compatibility and unique surface modification, while it is restricted by a low fluorescence property performance and an unclear fluorescence mechanism.
Xin Wang+8 more
doaj +1 more source
Dendrimers in gene delivery [PDF]
Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also ...
Dufès, Christine+2 more
core +1 more source
Structure of polyamidoamide dendrimers up to limiting generations : a mesoscale description [PDF]
The polyamidoamide (PAMAM) class of dendrimers was one of the first dendrimers synthesized by Tomalia and co-workers at Dow. Since its discovery the PAMAMs have stimulated many discussions on the structure and dynamics of such hyperbranched polymers ...
Goddard, William A., III+3 more
core +1 more source
Structure and Dynamics of DNA-dendrimer complexation: Role of counterions, water and base pair sequence [PDF]
We study sequence dependent complexation between oligonucleotides (single strand DNA) and various generation ethylene diamine (EDA) cored poly amido amide (PAMAM) dendrimers through atomistic molecular dynamics simulations accompanied by free energy calculations and inherent structure determination.
arxiv +1 more source
High Fluorescent Porphyrin-PAMAM-Fluorene Dendrimers [PDF]
Two new classes of dendrimers bearing 8 and 32 fluorene donor groups have been synthesized. The first and second generations of these porphyrin-PAMAM-fluorene dendrimers were characterized by 1H-NMR, 13C-NMR, FTIR, UV-vis spectroscopy, elemental analyses and MALDI-TOF mass spectrometry.
Garfias-Gonzalez, Karla+6 more
openaire +3 more sources
Nature of the Effective Interaction Between Dendrimers [PDF]
We have performed fully atomistic classical molecular dynamics (MD) simulations to calculate the effective interaction between two polyamidoamine (PAMAM) dendrimers. Using the umbrella sampling (US) technique, we have obtained the potential of mean force (PMF) between the dendrimers and investigated the effects of protonation level and dendrimer size ...
arxiv +1 more source
Rapid industrialization has resulted in serious heavy metal pollution. The removal of heavy metal ions from solutions is very important for environmental safety and human health.
Dandan Guo, Shaohua Huang, Yan Zhu
doaj +1 more source
Effect of the Generation of PAMAM Dendrimers on the Stabilization of Gold Nanoparticles
The behavior of small and intermediate generations of poly(amidoamine) (PAMAM) dendrimers and PAMAM|gold nanocomposites was studied by computational tools and experimental techniques. Molecular dynamics simulations were used to characterize at the atomic
F. Ávila-Salas+4 more
semanticscholar +1 more source