Various forms of tissue damage and danger signals following hematopoietic stem cell transplantation [PDF]
Hematopoietic stem cell transplantation (HSCT) is the most potent curative therapy for many malignant and non-malignant disorders. Unfortunately, a major complication of HSCT is graft-versus-host disease (GVHD), which is mediated by tissue damage ...
Abdulraouf eRamadan, Sophie ePaczesny
doaj +4 more sources
Synergy between immune system and antibiotics drives infection control in mice [PDF]
BackgroundAntibiotics and host immunity are traditionally viewed as independent defenses, with antibiotics reducing bacterial load to levels manageable by the immune system.
Rajalekshmy G. Padmakumari +13 more
doaj +2 more sources
Polyelectrolyte complexes (PECs) are attractive materials for drug delivery application as they offer simple preparations and high drug-loading efficiency.
Arie Wibowo +6 more
doaj +1 more source
Mechanisms of Toll-like receptor tolerance induced by microbial ligands
Some microorganisms can develop tolerance. On the one hand, it allows pathogenic microbes to escape immune surveillance, on the other hand, it provides the possibility to microbiota representatives to colonize different biotopes and build a symbiotic ...
Irina D. Bulgakova +2 more
doaj +1 more source
Application of bacterial therapeutic vaccine Immunovac-VP4 in the treatment of pollinosis [PDF]
In-depth study of the function and structure of the lymphoid tissue of the gastrointestinal tract and respiratory tract opens wide opportunities for the use of mucosal vaccines to improve immunity to various infectious agents.
M P Kostinov +3 more
doaj +1 more source
Using PAMPs and DAMPs as adjuvants in cancer vaccines
Immunotherapy for cancer has attracted considerable attention. As one of the immunotherapeutics, tumor vaccines exert great potential for cancer immunotherapy.
Huanyou Sun +10 more
doaj +1 more source
Plant Antimicrobial Peptides (PAMPs): Features, Applications, Production, Expression, and Challenges
The quest for an extraordinary array of defense strategies is imperative to reduce the challenges of microbial attacks on plants and animals. Plant antimicrobial peptides (PAMPs) are a subset of antimicrobial peptides (AMPs). PAMPs elicit defense against
Olalekan Olanrewaju Bakare +7 more
doaj +1 more source
Toll-Like Receptor 11 (TLR11) Interacts with Flagellin and Profilin through Disparate Mechanisms. [PDF]
Toll-like receptors (TLRs) are innate immune receptors that sense a variety of pathogen-associated molecular patterns (PAMPs) by interacting with them and subsequently initiating signal transduction cascades that elicit immune responses.
Hirotsugu Hatai +4 more
doaj +1 more source
The Arabidopsis NADPH oxidases RbohD and RbohF display differential expression patterns and contributions during plant immunity [PDF]
Plant NADPH oxidases, also known as respiratory burst oxidase homologues (RBOHs), produce reactive oxygen species (ROS) that perform a wide range of functions.
Antonio Molina +6 more
core +1 more source
MCMC-ODPR : primer design optimization using Markov Chain Monte Carlo sampling [PDF]
Background Next generation sequencing technologies often require numerous primer designs that require good target coverage that can be financially costly.
Allaby, Robin G. +3 more
core +3 more sources

