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Various forms of tissue damage and danger signals following hematopoietic stem cell transplantation [PDF]

open access: yesFrontiers in Immunology, 2015
Hematopoietic stem cell transplantation (HSCT) is the most potent curative therapy for many malignant and non-malignant disorders. Unfortunately, a major complication of HSCT is graft-versus-host disease (GVHD), which is mediated by tissue damage ...
Abdulraouf eRamadan, Sophie ePaczesny
doaj   +4 more sources

Synergy between immune system and antibiotics drives infection control in mice [PDF]

open access: yesFrontiers in Immunology
BackgroundAntibiotics and host immunity are traditionally viewed as independent defenses, with antibiotics reducing bacterial load to levels manageable by the immune system.
Rajalekshmy G. Padmakumari   +13 more
doaj   +2 more sources

Facile Fabrication of Polyelectrolyte Complex Nanoparticles Based on Chitosan – Poly-2-Acrylamido-2-Methylpropane Sulfonic Acid as a Potential Drug Carrier Material

open access: yesInternational Journal of Technology, 2021
Polyelectrolyte complexes (PECs) are attractive materials for drug delivery application as they offer simple preparations and high drug-loading efficiency.
Arie Wibowo   +6 more
doaj   +1 more source

Mechanisms of Toll-like receptor tolerance induced by microbial ligands

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2023
Some microorganisms can develop tolerance. On the one hand, it allows pathogenic microbes to escape immune surveillance, on the other hand, it provides the possibility to microbiota representatives to colonize different biotopes and build a symbiotic ...
Irina D. Bulgakova   +2 more
doaj   +1 more source

Application of bacterial therapeutic vaccine Immunovac-VP4 in the treatment of pollinosis [PDF]

open access: yesТерапевтический архив, 2018
In-depth study of the function and structure of the lymphoid tissue of the gastrointestinal tract and respiratory tract opens wide opportunities for the use of mucosal vaccines to improve immunity to various infectious agents.
M P Kostinov   +3 more
doaj   +1 more source

Using PAMPs and DAMPs as adjuvants in cancer vaccines

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Immunotherapy for cancer has attracted considerable attention. As one of the immunotherapeutics, tumor vaccines exert great potential for cancer immunotherapy.
Huanyou Sun   +10 more
doaj   +1 more source

Plant Antimicrobial Peptides (PAMPs): Features, Applications, Production, Expression, and Challenges

open access: yesMolecules, 2022
The quest for an extraordinary array of defense strategies is imperative to reduce the challenges of microbial attacks on plants and animals. Plant antimicrobial peptides (PAMPs) are a subset of antimicrobial peptides (AMPs). PAMPs elicit defense against
Olalekan Olanrewaju Bakare   +7 more
doaj   +1 more source

Toll-Like Receptor 11 (TLR11) Interacts with Flagellin and Profilin through Disparate Mechanisms. [PDF]

open access: yesPLoS ONE, 2016
Toll-like receptors (TLRs) are innate immune receptors that sense a variety of pathogen-associated molecular patterns (PAMPs) by interacting with them and subsequently initiating signal transduction cascades that elicit immune responses.
Hirotsugu Hatai   +4 more
doaj   +1 more source

The Arabidopsis NADPH oxidases RbohD and RbohF display differential expression patterns and contributions during plant immunity [PDF]

open access: yes, 2016
Plant NADPH oxidases, also known as respiratory burst oxidase homologues (RBOHs), produce reactive oxygen species (ROS) that perform a wide range of functions.
Antonio Molina   +6 more
core   +1 more source

MCMC-ODPR : primer design optimization using Markov Chain Monte Carlo sampling [PDF]

open access: yes, 2012
Background Next generation sequencing technologies often require numerous primer designs that require good target coverage that can be financially costly.
Allaby, Robin G.   +3 more
core   +3 more sources

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