Results 131 to 140 of about 91,705 (321)
Alarmins, inflammasomes and immunity
Biomedical Journal, 2012 The elaboration of an effective immune response against pathogenic microbes such as viruses, intracellular bacteria or protozoan parasites relies on the recognition of microbial products called pathogen-associated molecular patterns (PAMPs) by pattern ...
Najwane Saïd-Sadier, David M Ojcius
doaj +1 more source
Cytometry Part A, EarlyView.ABSTRACT For vaccination, the mechanisms of action of antigens and of immunostimulatory pathogen‐associated molecular pattern (PAMP) adjuvants are better understood than the roles of the depot, carrier, and other formulation‐related influences. Here, we carried out cytometric studies of vaccine formulations and the effect of adjuvant formulations on B ...
Egest J. Pone +3 more
wiley +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
Barrier Immunity, EarlyView.ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
Biofilm-associated molecular patterns: BAMPs
Infection and ImmunityChronic infections involving bacterial biofilms are a major clinical challenge due to the ability of biofilm to resist antimicrobial treatments and host immune responses.
Peter Østrup Jensen +2 more
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Fibroblast Plasticity in Inflammation of the Barrier
Barrier Immunity, EarlyView.Under inflammatory condition, fibroblasts in barrier tissues integrate inflammatory, senescent, and mechanical inputs. These pathways activate central signaling networks to drive fibroblast phenotypic transition, enabling cytokine production, immune cell recruitment, and extracellular matrix remodeling.
Chen Zhang, Hao Wu, Wei Li
wiley +1 more source
COPD disease severity and innate immune response to pathogen-associated molecular patterns
International Journal of COPD, 2016 Vincent S Fan,1,2 Sina A Gharib,2,3 Thomas R Martin,1,2 Mark M Wurfel2 1VA Puget Sound Health Care System, Seattle, WA, USA; 2Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Washington, Seattle WA, USA ...
Fan VS, Gharib SA, Martin TR, Wurfel MM
doaj
Molecular Plant-Microbe Interactions, 2008 Flagellin proteins derived from Pseudomonas syringae pv. tabaci 6605 and flg22Pa (QRLSTGSRINSAKDDAAGLQIA), one of the microbe-associated molecular patterns (MAMP) in bacterial flagellin, induce cell death and growth inhibition in Arabidopsis thaliana. To
Kana Naito +6 more
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HIV provides ample PAMPs for innate immune sensing [PDF]
Proceedings of the National Academy of Sciences, 2013 Viral genomes comprise either RNA or DNA, and sometimes both, as can happen with retroviruses at different stages of their life cycle. Viral nucleic acids are pathogen-associated molecular patterns (PAMPs) that are detected by a variety of pathogen-recognition receptors (PPRs), key components of the innate immune system.
openaire +2 more sources
Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo +7 more
wiley +1 more source
Different roles of Ca2+ and chitohexose in peanut (Arachis Hypogaea) photosynthetic responses to PAMP-immunity [PDF]
PeerJBackground During active infections, plants prevent further spread of pathogenic microorganisms by inducing the rapid programmed death of cells around the infection point.
Quan Wang +6 more
doaj +2 more sources