Results 81 to 90 of about 169,584 (184)

Genomic fluidity: an integrative view of gene diversity within microbial populations

BMC Genomics, 2011
Background The dual concepts of pan and core genomes have been widely adopted as means to assess the distribution of gene families within microbial species and genera.
Bergman Nicholas H, Haegeman Bart, Kislyuk Andrey O, Weitz Joshua S   +3 more
doaj   +1 more source

Draft Genome Sequences of Propionibacterium acnes Type Strain ATCC6919 and Antibiotic-Resistant Strain HL411PA1. [PDF]

, 2014
Propionibacterium acnes is a major skin commensal and is associated with acne vulgaris, the most common skin disease. Here we report the draft genome sequences of two P.
Bangayan, Nathanael Joshua, Barnard, Emma, Cheng, Alison, Craft, Noah, Curd, Emily, Li, Huiying, Liu, Jared   +6 more
core   +2 more sources

Application of Comparative Genomics for the Development of PCR Primers for the Detection of Harmful or Beneficial Microorganisms in Food: Mini-Review

Foods
Gene markers are widely utilized for detecting harmful and beneficial microorganisms in food products. Primer sequences targeting the 16S rRNA region, recognized as a conserved region, have been conventionally employed in PCR analyses.
Sang-Soon Kim
doaj   +1 more source

HUPAN: a pan-genome analysis pipeline for human genomes

Genome Biology, 2019
The human reference genome is still incomplete, especially for those population-specific or individual-specific regions, which may have important functions. Here, we developed a HUman Pan-genome ANalysis (HUPAN) system to build the human pan-genome.
Zhongqu Duan, Yuyang Qiao, Jinyuan Lu, Huimin Lu, Wenmin Zhang, Fazhe Yan, Chen Sun, Zhiqiang Hu, Zhen Zhang, Guichao Li, Hongzhuan Chen, Zhen Xiang, Zhenggang Zhu, Hongyu Zhao, Yingyan Yu, Chaochun Wei   +15 more
doaj   +1 more source

Population genomics of Vibrionaceae isolated from an endangered oasis reveals local adaptation after an environmental perturbation

BMC Genomics, 2020
Background In bacteria, pan-genomes are the result of an evolutionary “tug of war” between selection and horizontal gene transfer (HGT). High rates of HGT increase the genetic pool and the effective population size (N e ), resulting in open pan-genomes ...
Mirna Vázquez-Rosas-Landa, Gabriel Yaxal Ponce-Soto, Jonás A. Aguirre-Liguori, Shalabh Thakur, Enrique Scheinvar, Josué Barrera-Redondo, Enrique Ibarra-Laclette, David S. Guttman, Luis E. Eguiarte, Valeria Souza   +9 more
doaj   +1 more source

The diversity of a distributed genome in bacterial populations

, 2010
The distributed genome hypothesis states that the set of genes in a population of bacteria is distributed over all individuals that belong to the specific taxon. It implies that certain genes can be gained and lost from generation to generation.
Baumdicker, F., Hess, W. R., Pfaffelhuber, P.   +2 more
core   +1 more source

Genomic analysis of three African strains of Bacillus anthracis demonstrates that they are part of the clonal expansion of an exclusively pathogenic bacterium

New Microbes and New Infections, 2014
Bacillus anthracis is the causative agent of anthrax and is classified as a ‘Category A’ biological weapon. Six complete genomes of B. anthracis (A0248, Ames, Ames Ancestor, CDC684, H0491, and Sterne) are currently available. In this report, we add three
L. Rouli, M. Mbengue, C. Robert, M. Ndiaye, B. La Scola, D. Raoult   +5 more
doaj   +1 more source

Towards comparative pan-genomics

, 2020
Comparative genomics investigates the genomic makeup of species to unravel their unique variations and evolutionary relationships. High-throughput sequencing technologies have enabled reading the DNA content of a wide variety of species at an unprecedented rate.
openaire   +2 more sources

Indexing large genome collections on a PC

, 2014
Motivation: The availability of thousands of invidual genomes of one species should boost rapid progress in personalized medicine or understanding of the interaction between genotype and phenotype, to name a few applications.
Danek, Agnieszka, Deorowicz, Sebastian, Grabowski, Szymon   +2 more
core   +3 more sources

Micro-evolution of three Streptococcus species: selection, antigenic variation, and horizontal gene inflow

BMC Evolutionary Biology, 2019
Background The genus Streptococcus comprises pathogens that strongly influence the health of humans and animals. Genome sequencing of multiple Streptococcus strains demonstrated high variability in gene content and order even in closely related strains ...
Pavel V. Shelyakin, Olga O. Bochkareva, Anna A. Karan, Mikhail S. Gelfand   +3 more
doaj   +1 more source