Results 41 to 50 of about 39,007 (262)

Variable structure robust controller design for blood glucose regulation for type 1 diabetic patients: A backstepping approach

open access: yesIET Systems Biology, 2021
Diabetes mellitus type 1 occurs when β‐cells in the pancreas are destroyed by the immune system. As a result, the pancreas cannot produce adequate insulin, and the glucose enters the cells to produce energy.
Mohamadreza Homayounzade
doaj   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera   +6 more
wiley   +1 more source

The Artificial Pancreas

open access: yes, 2020
Purpose of review: Advances in diabetes technologies have enabled the development of artificial pancreas (closed-loop) systems for people with diabetes.

core   +1 more source

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach   +4 more
wiley   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

open access: yesAdvanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo   +4 more
wiley   +1 more source

Artificial pancreas: glycemic control strategies for avoiding hypoglycemia

open access: yesDyna, 2018
This paper examines the performance of two new closed-loop control strategies developed as part of the Artificial Pancreas project, this being the most promising treatment for type 1 diabetes mellitus.
Juan E. Sereno   +2 more
doaj   +1 more source

Automatic Insulin Delivery: Artificial Pancreas Controlled by Machine Learning Trained Algorithm Compared to other Therapies for Diabetes Treatment [PDF]

open access: yes, 2021
Hypothesis Diabetes Type 1 (DT1) therapy by means of artificial pancreas consisting of insulin pump with continuous glucose monitoring and hybrid "closed-loop" control algorithm trained with machine learning (ML) technology provides better glycemia ...
Peiro, Joan Carles
core  

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

open access: yesAdvanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni   +5 more
wiley   +1 more source

Automated closed-loop control of diabetes: the artificial pancreas

open access: yesBioelectronic Medicine, 2018
The incidence of Diabetes Mellitus is on the rise worldwide, which exerts enormous health toll on the population and enormous pressure on the healthcare systems.
Boris Kovatchev
doaj   +1 more source

Artificial pancreas: a technological solution for type 1 diabetes treatment

open access: yes, 2022
openNell’ elaborato vengono presentati gli sviluppi nel campo della tecnologia del pancreas artificiale. Sono analizzati i significativi progressi ingegneristici e i sostanziali progressi della bioelettronica nel rilevamento dei livelli di glucosio nel ...
MAZZELLA, BENEDETTA
core  

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