Results 51 to 60 of about 39,007 (262)

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

open access: yesAdvanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali   +4 more
wiley   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

open access: yesAdvanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy   +13 more
wiley   +1 more source

Anomaly Detection in the Artificial Pancreas [PDF]

open access: yes, 2020
The integration of subcutaneous sensing and insulin delivery technologies with novel control strategies has brought closer the development of the Artificial Pancreas. Nevertheless, thought recent developments are aimed at preventing chronic complications
Martínez, Ernesto, Avila, Luis
core   +1 more source

Hybrid Continuum Robot Designs and Architectures for Healthcare Applications

open access: yesAdvanced Robotics Research, EarlyView.
Hybrid continuum robots represent an emerging class of flexible manipulators that blend materials, structures, and actuation concepts from the established fields of soft and continuum robotics. This review introduces an accessible framework to distinguish key hybridization approaches, surveys current designs aimed at complex clinical applications, and ...
Burak Ozdemir   +4 more
wiley   +1 more source

Advances in artificial pancreas systems.

open access: yes, 2019
The artificial pancreas for managing type 1 diabetes has progressed from research into clinical practice, revealing areas for future ...

core   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

open access: yesAdvanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou   +4 more
wiley   +1 more source

Modeling the inter-day variability of insulin sensitivity in patients with type 1 diabetes through Markov models [PDF]

open access: yes, 2022
openThis paper focuses on a new technique which uses stochastic models (Markov models) to describe the inter-day variability of insulin sensitivity in patients with type 1 diabetes.
BABATO, DILETTA
core  

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

COMBINED LIVER-PANCREAS TRANSPLANTATION: THE FIRST RUSSIAN EXPERIENCE

open access: yesВестник трансплантологии и искусственных органов, 2010
Combined liver-pancreas transplantation is considered to be a reasonable treatment of patients with end-stage liver disease and concomitant insulin-dependent diabetes mellitus, so it may become a standard treatment of this category of patients. As known,
S. V. Gautier   +11 more
doaj   +1 more source

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