Results 111 to 120 of about 553,089 (317)

Correction: CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-IRNA-editing

Molecular Cancer, 2022
Peng Shen, Taoyue Yang, Qun Chen, Hao Yuan, Pengfei Wu, Baobao Cai, Lingdong Meng, Xumin Huang, Jiaye Liu, Yihan Zhang, Weikang Hu, Yi Miao, Zipeng Lu, Kuirong Jiang   +13 more
doaj   +1 more source

Targeting TNK2/ACK1 reverses the immunosuppressive tumor microenvironment and synergizes with immunochemotherapy in pancreatic cancer

Nature Communications
Pancreatic ductal adenocarcinoma (PDAC) remains highly lethal due to its aggressive nature and limited treatment options, with the efficacy of immunotherapy constrained by a uniquely immunosuppressive tumor microenvironment (TME).
Chao Wu, Weishuai Liu, Xiangting Hu, Yongjie Xie, Shengnan Li, Xinyue Liu, Zhaojun Sun, Xiaoling Li, Xin Yu, Yudong Yuan, Yiping Zou, Ran An, Yanan Chen, Hailong Wang, Yukuan Feng, Song Gao, Hongwei Wang, Yifei Wang, Nan Wang, Chao Yang, Jun Yu, Peiqing Sun, Chongbiao Huang, Antao Chang, Jihui Hao   +24 more
doaj   +1 more source

Refined, automatic nuclei segmentations in near-isotropic, reconstructed volume electron microscopy (FIB-SEM) of P7 mouse pancreas (jrc_mus-pancreas-4)

Segmentation description: Nuclei segmentations in jrc_mus-pancreas-4 using Cellpose 2.0 with minimal manual corrections.Software program: Cellpose 2.0Software program DOI: https://doi.org/10.1038/s41592-022-01663-4GPU: RTX A6000RAM: 256.0 GiBLabel voxel ...
Aubrey Weigel (9302851), David Ackerman (15452156), Jeff Rhoades (18114674), Yurii Zubov (18114698), CellMap Project Team (14322654)   +4 more
core   +1 more source

Bihormonal artificial pancreas for type 1 diabetes treatment

, 2022
reservedI pazienti diabetici hanno difficoltà a controllare i livelli di glicemia e soffrono degli effetti che può causare, tra cui episodi di iperglicemia e ipoglicemia che possono compromettere la salute del paziente.
FAVORIDO, CHRISTIAN
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Cancer Trends: Cancer of the pancreas

, 2012
Cancer of the pancreas accounts for approximately 2.5% of all invasive cancers and is the 9th most commonly diagnosed cancer in Ireland.1 Almost 400 cases of pancreatic cancer were diagnosed annually between 1994 and 2010 (Table 1).
National Cancer Registry Ireland (NCRI)
core  

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

artificial pancreas

openIl presente lavoro ha l'obiettivo di esplorare il concetto e l'applicazione del pancreas artificiale, uno strumento molto promettente per la gestione del diabete, fornendone un resoconto e soffermandosi sui componenti e sulla tecnologia che c’è alla
CELIN, TOMMASO
core  

Automatic nuclei segmentations in near-isotropic, reconstructed volume electron microscopy (FIB-SEM) of P7 mouse pancreas (jrc_mus-pancreas-4) model

Model description: Cellpose 2.0 was trained on nuclei from 17 2D slices from jrc_mus-pancreas-4.Architecture: Cellpose 2.0Input voxel size (nm): 128 x 128 x 128 (X, Y, Z)Output voxel size (nm): 128 x 128 x 128 (X, Y, Z)Classes trained on: NucleusGPU: RTX
Aubrey Weigel (9302851), CellMap Project Team (14322654)   +1 more
core   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source