Results 91 to 100 of about 714,927 (305)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

ANNULAR PANCREAS

Annals of Surgery, 1951
J R, ANDERSON, H, WAPSHAW
  +10 more sources

The impact of pancreatic duct stent placement on the clinically relevant postoperative pancreatic fistula rate for high-risk anastomoses: a systematic review and meta-analysis

BMC Gastroenterology
Background To evaluate the impact of pancreatic duct stent outcomes on the prognosis of postoperative pancreatic fistula in patients with high-risk anastomoses.
Yuran Dai, Xiaozhi Lu, Lei Jiang, Zipeng Lu, Kuirong Jiang, Yi Miao, Jishu Wei   +6 more
doaj   +1 more source

Wt1 is involved in pancreas development and adult pancreatic homeostasis [PDF]

, 2017
The embryonic mesothelium lining the visceral organs gives rise to mesenchymal cells through a localized epithelial-mesenchymal transition (EMT). This has been extensively studied in some cases, such as the heart, where the epicardium gives rise to ...
Aguilera, Beatriz, Ariza, Laura, Carmona, Rita, Cañete, Ana, Muñoz-Chápuli, Ramón   +4 more
core  

Pancreas divisum. Correlation between anatomical abnormalities and bile precipitation in the gallbladder in seven patients [PDF]

, 2016
Pancreas divisum is a genetic defect associated with recurrent acute pancreatitis due to insufficient drainage of the accessory pancreatic duct. Seven young patients diagnosed with pancreatic divisum and thickening of the gallbladder bile as shown on ...
AL MANSOUR, Monir, Biancucci, F, Costi, Umberto, DI CELLO, Pierfrancesco, Grande, Romualdo, Izzo, Luciano, Izzo, Paolo, Izzo, Sara, Muneer, A, Pugliese, Federico, Razionale, F, Sinaimeri, G, Valabrega, Stefano   +12 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Ferroptosis in cancer toward molecular insights and clinical translation in pancreatic cancer

Molecular Cancer
Ferroptosis is a regulated form of cell death driven by iron accumulation and lipid peroxidation. Since its recognition as a modality of regulated cell death, ferroptosis has attracted increasing attention in cancer research for its distinct metabolic ...
Qun Chen, Fengyuan Liu, Yufeng Zhang, Lingtao Yan, Yang Wu, Dong Xu, Pengfei Wu, Hao Yuan, Kuirong Jiang   +8 more
doaj   +1 more source

Augmenter of liver regeneration enhances the success rate of fetal pancreas transplantation in rodents [PDF]

, 1998
Background. Treatment of fetal pancreas (FP) isografts with insulin- like growth factor-I greatly improves the rate of conversion to euglycemia in diabetic rats.
Adams, Adams, Andersson, Donald C. Dafoe, Eckhoff, Edward J. Alfrey, Elizabeth C. Squiers, Francavilla, Gregg A. Adams, Hagiya, Hullett, Katz, Marcello Maestri, Mullen, Ogasawara, Rabinovitch, Sieradzki, Sutherland, Thomas E. Starzl, Tuch, Tuch, Wang   +21 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source