Results 91 to 100 of about 553,089 (317)
Ferroptosis in cancer toward molecular insights and clinical translation in pancreatic cancer
Molecular CancerFerroptosis is a regulated form of cell death driven by iron accumulation and lipid peroxidation. Since its recognition as a modality of regulated cell death, ferroptosis has attracted increasing attention in cancer research for its distinct metabolic ...
Qun Chen +8 more
doaj +1 more source
Biopolymers for Bioartificial Pancreas [PDF]
, 2018 The concept of the bioartificial pancreas has developed substantially in the last decade, after the first successful islet transplantation in 2000. Islets are clusters of endocrine cells found in the pancreas.
Odugbemi, M.
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4
Journal of Experimental & Clinical Cancer Research, 2018 Background The aberrant expression of microRNAs (miRNAs) has emerged as important hallmarks of cancer. However, the molecular mechanisms underlying the differences of miRNA expression remain unclear.
Yue Fu +7 more
doaj +1 more source
Epidermal growth factor induces cell proliferation in mouse pancreas and salivary glands
, 1997 Epidermal growth factor (EGF) is a mitogenic stimulus in many tissues and occurs in large amounts in the pancreas and salivary glands. Whether EGF is mitogenic in the pancreas is controversial, and the EGF effect has not been studied in the salivary ...
Ihse, Ingemar, +4 more
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FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Rare Pancreatic Anomaly: Annular Pancreas
Acute pancreatitis is defined as inflammation of the pancreas gland accompanied by abdominal pain and elevated levels of amylase and lipase. The reported annual incidence of acute pancreatitis varies between 4.9 and 35 per 100 000 people.
Mehmet Suat Yalçın +4 more
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Expression of Wnt target genes in solid pseudopapillary tumor of the pancreas: a pilot study
, 2009 OBJECTIVES: Solid pseudopapillary tumor (SPT) of the pancreas is very rare. This study was performed to analyze the expression of Wnt signal target genes (matrix metalloproteinase-7 [MMP-7], cyclin-D1, and c-myc) and Ki-67 in resected SPTs to determine ...
최기홍 +6 more
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Perineurioma of the Pancreas: A Rare Case [PDF]
, 2012 Context Mesenchymal tumors of pancreas are rare. Case report We describe a case of perineurioma involving the body and tail of pancreas presenting as a slow growing abdominal lump. Conclusion Though perineurioma may arise from variety of anatomical sites
Jha, Ashesh +5 more
core +1 more source