Results 81 to 90 of about 553,089 (317)
Diabetes, 2012 The discovery of insulin was lifesaving. However, it converted type 1 diabetes, which had been an acute and lethal disease, into a chronic disease, with its attendant complications. It had long been considered—and was clearly demonstrated in the Diabetes Control and Complications Trial (1)—that microvascular complications such as retinopathy ...
openaire +2 more sources
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
BMC GastroenterologyBackground To evaluate the impact of pancreatic duct stent outcomes on the prognosis of postoperative pancreatic fistula in patients with high-risk anastomoses.
Yuran Dai +6 more
doaj +1 more source
Pancreas structure and function
, 2010 This topic starts with a labelled diagram, showing the position of the pancreas in relation to the jejunum and small intestine. A table clearly differentiates the pancreas as an exocrine and endocrine gland.
Jean Shapcott +1 more
core
Post-surgical Pancreatitis Masquerading as Recurrent Neuroendocrine Cancer [PDF]
, 2010 Neuroendocrine tumours of the pancreas can have a spectrum of behaviour from relatively benign to aggressive. Resection can result in cure although metastatic disease is described.
Oniscu, Anca +5 more
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Molecular and Clinical Markers of Pancreas Cancer [PDF]
, 2010 Pancreas cancer has the worst prognosis of any solid tumor but is potentially treatable if it is diagnosed at an early stage. Thus there is critical interest in delineating clinical and molecular markers of incipient disease.
Buxbaum, James L, Eloubeidi, Mohamad A
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Journal of Hepatocellular CarcinomaJiajing Zhao,1 Yunjian Meng,2 Zhongyi Jiang,1 Zhike Li,1 Youyao Li,1 Yuanjun Liu,2 Yuandi Zeng,1,2 Shaobo Dai,1,2 Zhiyong Du,1,2 Liping Liu1,2 1Department of Hepatobiliary and Pancreas Surgery, Shenzhen People’s Hospital, The Second Clinical Medical ...
Zhao J +9 more
doaj