Results 11 to 20 of about 641,720 (354)
Molecular Cancer, 2021 Background Extensive studies have demonstrated the pivotal roles of circular RNAs (circRNAs) in the occurrence and development of different human cancers. However, the expression and regulatory roles of circRNAs in pancreatic ductal adenocarcinoma (PDAC)
Zeyin Rong +10 more
doaj +1 more source
Pancreatic resection for pancreatic cancer [PDF]
HPB, 2006 Ductal pancreatic adenocarcinoma, the most frequent malignancy of the pancreas, is characterized by retroperitoneal and perineural infiltration, early formation of multiple metastases, and resistance to most of the treatment regimens currently available.
M E Martignoni +4 more
openaire +3 more sources
BMC Gastroenterology, 2023 Background The effectiveness of chemotherapy in older adult patients with biliary tract cancer (BTC) remains to be established, despite the fact that the majority of patients diagnosed with BTC tend to be aged ≥ 70 years.
Takeru Hirao +16 more
doaj +1 more source
Annual Review of Pathology: Mechanisms of Disease, 2007 The past two decades have witnessed an explosion in our understanding of pancreatic cancer, and it is now clear that pancreatic cancer is a disease of inherited (germ-line) and somatic gene mutations. The genes mutated in pancreatic cancer include KRAS2, p16/CDKN2A, TP53, and SMAD4/DPC4, and these are accompanied by a substantial compendium of genomic ...
Anirban, Maitra, Ralph H, Hruban
openaire +2 more sources
Pancreatitis and Pancreatic Cancer Risk
Technology in Cancer Research & Treatment, 2023 Purpose: The present retrospective study aimed to explore the relationship between pancreatitis and pancreatic cancer in the population cohort of the UK Biobank (UKB) ( https://www.ukbiobank.ac.uk ). Methods: From the 500 thousand population cohort of UKB, according to the age and gender of patients with pancreatic cancer 1:10, matching the control ...
Dong-Mei Ma +6 more
openaire +3 more sources
Cancer Cell International, 2021 Background ALDOA is a glycolytic enzyme found mainly in developing embryos, adult muscle and various malignant tumours, including pancreatic tumours. Our previous study revealed that ALDOA, an oncogene, can promote the proliferation and metastasis of ...
Haidi Chen +11 more
doaj +1 more source
Trials, 2023 Background Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Radical surgical resection offers the only potential cure. There is increasing agreement that radical antegrade modular pancreatosplenectomy (RAMPS) may benefit ...
Jialin Li +11 more
doaj +1 more source
Pancreatic cancer-associated diabetes mellitus: an open field for proteomic applications. [PDF]
, 2005 Background: Diabetes mellitus is associated with pancreatic cancer in more than 80% of the cases. Clinical, epidemiological, and experimental data indicate that pancreatic cancer causes diabetes mellitus by releasing soluble mediators which interfere ...
BALDO G +11 more
core +1 more source
Interethnic differences in pancreatic cancer incidence and risk factors: The Multiethnic Cohort. [PDF]
, 2019 While disparity in pancreatic cancer incidence between blacks and whites has been observed, few studies have examined disparity in other ethnic minorities. We evaluated variations in pancreatic cancer incidence and assessed the extent to which known risk
Haiman, Christopher A +8 more
core +1 more source
Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma
Journal of Hematology & Oncology, 2020 Pancreatic ductal adenocarcinoma (PDAC) is a malignancy characterized by a poor prognosis and high mortality rate. Genetic mutations and altered molecular pathways serve as targets in precise therapy.
Yunzhen Qian +10 more
doaj +1 more source