The fear of cancer recurrence and progression in patients with pancreatic cancer [PDF]
, 2022 PURPOSE: It is plausible that patients with pancreatic cancer experience fear of tumor recurrence or progression (FOP). The aim of this study was to compare FOP in patients with pancreatic cancer treated with surgical resection, palliative systemic ...
for the Dutch Pancreatic Cancer Group
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Frontiers in Immunology, 2021 Background: The treatment modalities for pancreatic ductal adenocarcinoma (PDAC) are limited and unsatisfactory. Although many novel drugs targeting the tumor microenvironment, such as immune checkpoint inhibitors, have shown promising efficacy for some ...
Rong Tang +43 more
doaj +1 more source
Preoperative misdiagnosis of pancreatic and periampullary cancer in patients undergoing pancreatoduodenectomy: A multicentre retrospective cohort study [PDF]
, 2021 Introduction: Whereas neoadjuvant chemo(radio)therapy is increasingly used in pancreatic cancer, it is currently not recommended for other periampullary (non-pancreatic) cancers.
for the Dutch Pancreatic Cancer Group
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Chronic Pancreatitis and Pancreatic Cancer [PDF]
Gastroenterology, 2014 <b><i>Background:</i></b> Pancreatic cancer (PC) is one of the most lethal diseases with an incidence rate almost equal to the rate of mortality. Chronic pancreatitis (CP) is a common chronic inflammatory disease of unknown etiology that affects the pancreas.
Bai-Rong, Li +2 more
openaire +4 more sources
Frontiers in Oncology, 2021 BackgroundCancer stem cells (CSCs) are widely thought to contribute to the dismal prognosis of pancreatic ductal adenocarcinoma (PDAC). CSCs share biological features with adult stem cells, such as longevity, self-renewal capacity, differentiation, drug ...
Rong Tang +43 more
doaj +1 more source
Pancreatic resection for pancreatic cancer [PDF]
HPB, 2006 Ductal pancreatic adenocarcinoma, the most frequent malignancy of the pancreas, is characterized by retroperitoneal and perineural infiltration, early formation of multiple metastases, and resistance to most of the treatment regimens currently available.
Bachmann, Jeannine +4 more
openaire +2 more sources
Pancreatitis and Pancreatic Cancer Risk
Technology in Cancer Research & Treatment, 2023 Purpose: The present retrospective study aimed to explore the relationship between pancreatitis and pancreatic cancer in the population cohort of the UK Biobank (UKB) ( https://www.ukbiobank.ac.uk ). Methods: From the 500 thousand population cohort of UKB, according to the age and gender of patients with pancreatic cancer 1:10, matching the control ...
Dong-Mei Ma +6 more
openaire +3 more sources
Nationwide Impact of Centralization, Neoadjuvant Therapy, Minimally Invasive Surgery, and Standardized Pathology Reporting on R0 Resection and Overall Survival in Pancreatoduodenectomy for Pancreatic Cancer [PDF]
, 2023 Background: Surgeons aim for R0 resection in patients with pancreatic cancer to improve overall survival. However, it is unclear whether recent changes in pancreatic cancer care such as centralization, increased use of neoadjuvant therapy, minimally ...
Dutch Pancreatic Cancer Group
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Pevonedistat Suppresses Pancreatic Cancer Growth via Inactivation of the Neddylation Pathway
Frontiers in Oncology, 2022 BackgroundThe neddylation pathway is aberrantly overactivated in multiple human cancers and has been indicated as an effective target for anticancer therapy in clinical trials.
Junfeng Xu +43 more
doaj +1 more source
Impact of multicentre diagnostic workup in patients with pancreatic cancer on repeated diagnostic investigations, time-to-diagnosis and time-to-treatment: A nationwide analysis [PDF]
, 2022 Background: Due to the centralization of pancreatic surgery, patients with suspected pancreatic cancer may undergo diagnostic workup in both a non-pancreatic centre and a pancreatic centre, i.e. multicentre workup.
Dutch Pancreatic Cancer Group
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