Results 11 to 20 of about 5,871,156 (346)

Pancreatic cancer [PDF]

open access: yesCA: A Cancer Journal for Clinicians, 1994
Pancreatic cancer is a devastating disease for the patient and presents challenging diagnostic and management problems for the physician. A range of serologic and radiologic studies are available for evaluation and staging of this disease. However, invasive studies, including laparotomy, are often necessary to establish the diagnosis and resectability.
M M, Murr   +3 more
openaire   +4 more sources

Carbohydrate antigen 125 supplements carbohydrate antigen 19-9 for the prediction of invasive intraductal papillary mucinous neoplasms of the pancreas

open access: yesWorld Journal of Surgical Oncology, 2022
Background Intraductal papillary mucinous neoplasms (IPMNs) are characterized by their abundant mucin production and malignant potential. IPMNs of the pancreas are mainly managed according to their radiographic indications, but this approach lacks ...
Yunzhen Qian   +12 more
doaj   +1 more source

Pancreatic Cancer: Changing Epidemiology and New Approaches to Risk assessment, Early Detection, and Prevention.

open access: yesGastroenterology, 2023
Pancreatic cancer usually results in poor survival with limited options for treatment, as most affected individuals present with advanced disease. Early detection of pre-invasive pancreatic neoplasia and identifying molecular therapeutic targets provide ...
E. Stoffel, R. Brand, M. Goggins
semanticscholar   +1 more source

Pancreatic cancer [PDF]

open access: yesBMJ, 2014
In recent years, it has become clear that the current standard therapeutic options for pancreatic cancer are not adequate and still do not meet the criteria to cure patients suffering from this lethal disease. Although research over the past decade has shown very interesting and promising new therapeutic options for these patients, only minor clinical ...
Ajith K, Siriwardena   +1 more
openaire   +4 more sources

Pancreatic cancer

open access: yesThe Lancet, 2016
Pancreatic cancer is a highly lethal disease, for which mortality closely parallels incidence. Most patients with pancreatic cancer remain asymptomatic until the disease reaches an advanced stage. There is no standard programme for screening patients at high risk of pancreatic cancer (eg, those with a family history of pancreatic cancer and chronic ...
Terumi, Kamisawa   +3 more
  +10 more sources

Radical antegrade modular pancreatosplenectomy (RAMPS) versus standard retrograde pancreatosplenectomy (SRPS) for resectable body and tail pancreatic adenocarcinoma: protocol of a multicenter, prospective, randomized phase III control trial (CSPAC-3)

open access: yesTrials, 2023
Background Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Radical surgical resection offers the only potential cure. There is increasing agreement that radical antegrade modular pancreatosplenectomy (RAMPS) may benefit ...
Jialin Li   +11 more
doaj   +1 more source

Pancreatic cancer: A review of epidemiology, trend, and risk factors

open access: yesWorld Journal of Gastroenterology, 2021
Despite rapid advances in modern medical technology and significant improvements in survival rates of many cancers, pancreatic cancer is still a highly lethal gastrointestinal cancer with a low 5-year survival rate and difficulty in early detection.
Jiannan Hu   +6 more
semanticscholar   +1 more source

Resected Pancreatic Cancer With N2 Node Involvement Is Refractory to Gemcitabine-Based Adjuvant Chemotherapy

open access: yesCancer Control, 2020
Lymphatic metastasis is a major determinant of the outcome of resected pancreatic cancer. Gemcitabine-based adjuvant chemotherapy can improve the outcome of resected pancreatic cancer.
Chen Liu MD, PhD   +10 more
doaj   +1 more source

ALDOA inhibits cell cycle arrest induced by DNA damage via the ATM-PLK1 pathway in pancreatic cancer cells

open access: yesCancer Cell International, 2021
Background ALDOA is a glycolytic enzyme found mainly in developing embryos, adult muscle and various malignant tumours, including pancreatic tumours. Our previous study revealed that ALDOA, an oncogene, can promote the proliferation and metastasis of ...
Haidi Chen   +11 more
doaj   +1 more source

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