Results 11 to 20 of about 457,954 (260)

Radical antegrade modular pancreatosplenectomy (RAMPS) versus standard retrograde pancreatosplenectomy (SRPS) for resectable body and tail pancreatic adenocarcinoma: protocol of a multicenter, prospective, randomized phase III control trial (CSPAC-3)

Trials, 2023
Background Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Radical surgical resection offers the only potential cure. There is increasing agreement that radical antegrade modular pancreatosplenectomy (RAMPS) may benefit ...
Jialin Li, Si Shi, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Hang Xu, Miaoyan Wei, Bo Zhang, Jin Xu, Wei Wang, Xianjun Yu   +11 more
doaj   +1 more source

ALDOA inhibits cell cycle arrest induced by DNA damage via the ATM-PLK1 pathway in pancreatic cancer cells

Cancer Cell International, 2021
Background ALDOA is a glycolytic enzyme found mainly in developing embryos, adult muscle and various malignant tumours, including pancreatic tumours. Our previous study revealed that ALDOA, an oncogene, can promote the proliferation and metastasis of ...
Haidi Chen, Zeng Ye, Xiaowu Xu, Yi Qin, Changfeng Song, Guixiong Fan, Haifeng Hu, Yuheng Hu, Xianjun Yu, Wensheng Liu, Shunrong Ji, Wenyan Xu   +11 more
doaj   +1 more source

Pancreatic cancer [PDF]

The Lancet, 2011
Substantial progress has been made in our understanding of the biology of pancreatic cancer, and advances in patients' management have also taken place. Evidence is beginning to show that screening first-degree relatives of individuals with several family members affected by pancreatic cancer can identify non-invasive precursors of this malignant ...
Audrey, Vincent, Joseph, Herman, Rich, Schulick, Ralph H, Hruban, Michael, Goggins   +4 more
openaire   +2 more sources

Pancreatic cancer

Nature Reviews Disease Primers, 2016
Pancreatic cancer is the fourth leading cause of death for neoplasm in western countries. Surgery still remains the treatment of choice although almost 80% of patients are not resectable at diagnosis because of liver metastases and the 5-year overall survival of patients treated with surgery is only (20%).
Falconi M., Tamburrino D., Buzzetti E., Partelli S.   +3 more
  +12 more sources

Advances on diagnostic biomarkers of pancreatic ductal adenocarcinoma: A systems biology perspective

Computational and Structural Biotechnology Journal, 2020
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy that is usually diagnosed at an advanced stage when curative surgery is no longer an option.
Wu-Hu Zhang, Wen-Quan Wang, Xuan Han, He-Li Gao, Tian-Jiao Li, Shuai-Shuai Xu, Shuo Li, Hua-Xiang Xu, Hao Li, Long-Yun Ye, Xuan Lin, Chun-Tao Wu, Jiang Long, Xian-Jun Yu, Liang Liu   +14 more
doaj   +1 more source

Nationwide evaluation of pancreatic cancer networks ten years after the centralization of pancreatic surgery [PDF]

, 2023
Background: Due to centralization of pancreatic surgery, patients with pancreatic cancer are treated in pancreatic cancer networks, composed of referring hospitals (Spokes) and an expert center (Hub).
Dutch Pancreatic Cancer Group
core  

Pancreatic cancer

European Journal of Surgical Oncology, 2023
The need for a common education and training track in surgical oncology across Europe has been emphasized. ESSO provides several hands-on courses for skills training and face-to-face discussions. The core curriculum provides a framework for the overall theoretical requirements in surgical oncology. The UEMS/EBSQ fellowship exam is designed to test core
Kjetil Søreide, Elena Rangelova, Christina Dopazo, Sven Mieog, Stefan Stättner   +4 more
openaire   +6 more sources

Challenges of drug resistance in the management of pancreatic cancer [PDF]

, 2010
The current treatment of choice for metastatic pancreatic cancer involves single agent gemcitabine or combination of gemcitabine with capecitabine and erlotinib (tyrosine kinase inhibitor).
Naomi Walsh, Martin Clynes, Rizwan Sheikh, Sheikh, Rizwan, O'Connor, Robert A., Robert O’Connor, Ray McDermott, O'Connor, Robert, Clynes, Martin, Walsh, Naomi, McDermott, Ray   +10 more
core   +1 more source

From the Immune Profile to the Immunoscore: Signatures for Improving Postsurgical Prognostic Prediction of Pancreatic Neuroendocrine Tumors

Frontiers in Immunology, 2021
ObjectiveImmune infiltration plays an important role in tumor development and progression and shows promising prognostic value in numerous tumors. In this study, we aimed to identify the role of immune infiltration in pancreatic neuroendocrine tumors ...
Miaoyan Wei, Miaoyan Wei, Miaoyan Wei, Miaoyan Wei, Miaoyan Wei, Jin Xu, Jin Xu, Jin Xu, Jin Xu, Jin Xu, Jie Hua, Jie Hua, Jie Hua, Jie Hua, Jie Hua, Qingcai Meng, Qingcai Meng, Qingcai Meng, Qingcai Meng, Qingcai Meng, Chen Liang, Chen Liang, Chen Liang, Chen Liang, Chen Liang, Jiang Liu, Jiang Liu, Jiang Liu, Jiang Liu, Jiang Liu, Bo Zhang, Bo Zhang, Bo Zhang, Bo Zhang, Bo Zhang, Wei Wang, Wei Wang, Wei Wang, Wei Wang, Wei Wang, Xianjun Yu, Xianjun Yu, Xianjun Yu, Xianjun Yu, Xianjun Yu, Si Shi, Si Shi, Si Shi, Si Shi, Si Shi   +49 more
doaj   +1 more source

Identification of pancreatic cancer invasion-related proteins by proteomic analysis [PDF]

, 2009
Background – Markers of pancreatic cancer invasion were investigated in two clonal populations of the cell line, MiaPaCa-2, Clone #3 (high invasion) and Clone #8 (low invasion) using proteomic profiling of an in vitro model of pancreatic cancer ...
Naomi Walsh, Walsh Naomi, Martin Clynes, Meleady Paula, Henry Michael, Clynes, Martin, Kennedy Susan, Susan Kennedy, O'Donovan, Norma, Clynes Martin, Michael Henry, Walsh, Naomi, Dowling, Paul, Paula Meleady, O'Donovan Norma, Meleady, Paula, Norma O'Donovan, Kennedy, Susan, O\u27Donovan, Norma, Henry, Michael, Dowling Paul, Paul Dowling   +21 more
core   +1 more source