Results 21 to 30 of about 409,500 (188)
Radical antegrade modular pancreatosplenectomy (RAMPS) versus standard retrograde pancreatosplenectomy (SRPS) for resectable body and tail pancreatic adenocarcinoma: protocol of a multicenter, prospective, randomized phase III control trial (CSPAC-3)
Trials, 2023 Background Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Radical surgical resection offers the only potential cure. There is increasing agreement that radical antegrade modular pancreatosplenectomy (RAMPS) may benefit ...Jialin Li, Si Shi, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Hang Xu, Miaoyan Wei, Bo Zhang, Jin Xu, Wei Wang, Xianjun Yu +11 moredoaj +1 more sourceResected Pancreatic Cancer With N2 Node Involvement Is Refractory to Gemcitabine-Based Adjuvant Chemotherapy
Cancer Control, 2020 Lymphatic metastasis is a major determinant of the outcome of resected pancreatic cancer. Gemcitabine-based adjuvant chemotherapy can improve the outcome of resected pancreatic cancer.Chen Liu MD, PhD, He Cheng MD, Kaizhou Jin MD, PhD, Zhiyao Fan MD, Yitao Gong MD, Yunzhen Qian MD, Shengming Deng MD, Qiuyi Huang MD, Quanxing Ni MD, Xianjun Yu MD, PhD, Guopei Luo MD, PhD +10 moredoaj +1 more sourceCarbohydrate antigen 125 supplements carbohydrate antigen 19-9 for the prediction of invasive intraductal papillary mucinous neoplasms of the pancreas
World Journal of Surgical Oncology, 2022 Background Intraductal papillary mucinous neoplasms (IPMNs) are characterized by their abundant mucin production and malignant potential. IPMNs of the pancreas are mainly managed according to their radiographic indications, but this approach lacks ...Yunzhen Qian, Yitao Gong, Guopei Luo, Yu Liu, Ruijie Wang, Xuan Zou, Shengming Deng, Xuan Lin, Yusheng Chen, Xu Wang, Xianjun Yu, He Cheng, Chen Liu +12 moredoaj +1 more sourceMolecular alterations and targeted therapy in pancreatic ductal adenocarcinoma
Journal of Hematology & Oncology, 2020 Pancreatic ductal adenocarcinoma (PDAC) is a malignancy characterized by a poor prognosis and high mortality rate. Genetic mutations and altered molecular pathways serve as targets in precise therapy.Yunzhen Qian, Yitao Gong, Zhiyao Fan, Guopei Luo, Qiuyi Huang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Chen Liu +10 moredoaj +1 more sourcePancreatic Cancer [PDF]
Annual Review of Pathology: Mechanisms of Disease, 2007 The past two decades have witnessed an explosion in our understanding of pancreatic cancer, and it is now clear that pancreatic cancer is a disease of inherited (germ-line) and somatic gene mutations. The genes mutated in pancreatic cancer include KRAS2, p16/CDKN2A, TP53, and SMAD4/DPC4, and these are accompanied by a substantial compendium of genomic ...Anirban, Maitra, Ralph H, Hrubanopenaire +2 more sourcesPancreatitis and Pancreatic Cancer Risk
Technology in Cancer Research & Treatment, 2023 Purpose: The present retrospective study aimed to explore the relationship between pancreatitis and pancreatic cancer in the population cohort of the UK Biobank (UKB) ( https://www.ukbiobank.ac.uk ). Methods: From the 500 thousand population cohort of UKB, according to the age and gender of patients with pancreatic cancer 1:10, matching the control ...Dong-Mei Ma, Xiao-Wu Dong, Xiao Han, Zhi Ling, Guo-Tao Lu, Yun-Yun Sun, Xu-Dong Yin +6 moreopenaire +3 more sourcesPancreatic resection for pancreatic cancer [PDF]
HPB, 2006 Ductal pancreatic adenocarcinoma, the most frequent malignancy of the pancreas, is characterized by retroperitoneal and perineural infiltration, early formation of multiple metastases, and resistance to most of the treatment regimens currently available.M E Martignoni, Helmut Friess, Markus W. Büchler, Jeannine Bachmann, Christoph W. Michalski +4 moreopenaire +3 more sourcesFrom the Immune Profile to the Immunoscore: Signatures for Improving Postsurgical Prognostic Prediction of Pancreatic Neuroendocrine Tumors
Frontiers in Immunology, 2021 ObjectiveImmune infiltration plays an important role in tumor development and progression and shows promising prognostic value in numerous tumors. In this study, we aimed to identify the role of immune infiltration in pancreatic neuroendocrine tumors ...Miaoyan Wei, Miaoyan Wei, Miaoyan Wei, Miaoyan Wei, Miaoyan Wei, Jin Xu, Jin Xu, Jin Xu, Jin Xu, Jin Xu, Jie Hua, Jie Hua, Jie Hua, Jie Hua, Jie Hua, Qingcai Meng, Qingcai Meng, Qingcai Meng, Qingcai Meng, Qingcai Meng, Chen Liang, Chen Liang, Chen Liang, Chen Liang, Chen Liang, Jiang Liu, Jiang Liu, Jiang Liu, Jiang Liu, Jiang Liu, Bo Zhang, Bo Zhang, Bo Zhang, Bo Zhang, Bo Zhang, Wei Wang, Wei Wang, Wei Wang, Wei Wang, Wei Wang, Xianjun Yu, Xianjun Yu, Xianjun Yu, Xianjun Yu, Xianjun Yu, Si Shi, Si Shi, Si Shi, Si Shi, Si Shi +49 moredoaj +1 more sourceCrosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives
Molecular Cancer, 2021 Cancer-associated fibroblasts (CAFs), a stromal cell population with cell-of-origin, phenotypic and functional heterogeneity, are the most essential components of the tumor microenvironment (TME).Xiaoqi Mao, Jin Xu, Wei Wang, Chen Liang, Jie Hua, Jiang Liu, Bo Zhang, Qingcai Meng, Xianjun Yu, Si Shi +9 moredoaj +1 more sourceHypermutation In Pancreatic Cancer [PDF]
Gastroenterology, 2017 Pancreatic cancer is molecularly diverse, with few effective therapies. Increased mutation burden and defective DNA repair are associated with response to immune checkpoint inhibitors in several other cancer types. We interrogated 385 pancreatic cancer genomes to define hypermutation and its causes. Mutational signatures inferring defects in DNA repair Ivana Cataldo, Andrew V. Biankin, Anirban Maitra, Anthony J. Gill, Anthony J. Gill, Anthony J. Gill, Andreia V. Pinho, Nikolajs Zeps, Richard D. Schulick, Marc D. Jones, Marc D. Jones, Oliver Hofmann, Timothy J. C. Bruxner, Felicity Newell, Felicity Newell, Skye McKay, John V. Pearson, John V. Pearson, Margaret A. Tempero, Jaswinder S. Samra, Jaswinder S. Samra, Conrad Leonard, Conrad Leonard, Ivon Harliwong, Marc Giry-Laterriere, Matthew J. Anderson, Andrew Barbour, Roberto Salvia, Fraser Duthie, Nicola Waddell, Nicola Waddell, Amanda Mawson, Oliver Holmes, Oliver Holmes, Peter J. Wilson, Ilse Rooman, Suzanne Manning, J. Lynn Fink, Giampaolo Tortora, Nick Waddell, Craig Nourse, Craig Nourse, Robert Grützmann, Angelika N. Christ, Nigel B. Jamieson, Nigel B. Jamieson, Karin A. Oien, C. Ross Carter, Jeremy L. Humphris, Venessa T. Chin, Christopher J. Scarlett, Christopher J. Scarlett, Peter Bailey, Peter Bailey, Christine A. Iacobuzio-Donahue, Rita T. Lawlor, Janet Graham, Janet Graham, Marina Pajic, Marina Pajic, Jennifer P. Morton, Ronald S Mead, Karin S. Kassahn, Karin S. Kassahn, David Miller, David Miller, Mark Pinese, Lorraine A. Chantrill, Lorraine A. Chantrill, David K. Chang, Angela Chou, Angela Chou, Stephen H. Kazakoff, Stephen H. Kazakoff, Owen J. Sansom, Krishna Epari, Nam Q. Nguyen, Ann-Marie Patch, Ann-Marie Patch, Elizabeth A. Musgrove, Elizabeth A. Musgrove, Elizabeth A. Musgrove, Andrew Stone, Christopher L. Wolfgang, Christian Pilarsky, Ehsan Nourbakhsh, Katia Nones, Katia Nones, Borislav Rusev, Neil D. Merrett, Jianmin Wu, Vincenzo Corbo, Senel Idrisoglu, Colin J. McKay, Ralph H. Hruban, Sean M. Grimmond, Sean M. Grimmond, Qinying Xu, Qinying Xu, Euan J. Dickson, Christopher W. Toon, Mark J. Cowley, Mark J. Cowley, Amber L. Johns, Adnan Nagrial, James R. Eshleman, James G. Kench, James G. Kench, James G. Kench, Aldo Scarpa, Jane Hair, Scott Wood, Scott Wood, Michael C.J. Quinn, Michael C.J. Quinn, Richard A. Morgan +115 moreopenaire +5 more sources
