Serotonin and pancreatic duct function [PDF]
1. 5-HT inhibits spontaneous fluid secretion as well as stimulated secretion with secretin (cAMP mediated) or ACh (Ca2+ mediated) in the isolated guinea pig pancreatic ducts. 2. The inhibitory effect of 5-HT is reversible and is dependent on the concentration in the range 0.01-0.1 microM, which is much lower than those that affect intestinal motility ...
S, Naruse +8 more
openaire +2 more sources
Pancreatic ductal adenocarcinoma [PDF]
A 61-year-old gentleman who lives with his wife and 20-year-old son, presented to the polyclinic with a four week history of pruritus. On examination he was found to be jaundiced and his LFTs were high.
Bezzina, Sarah, Debattista, Daniel
core
Pancreas divisum. Correlation between anatomical abnormalities and bile precipitation in the gallbladder in seven patients [PDF]
Pancreas divisum is a genetic defect associated with recurrent acute pancreatitis due to insufficient drainage of the accessory pancreatic duct. Seven young patients diagnosed with pancreatic divisum and thickening of the gallbladder bile as shown on ...
AL MANSOUR, Monir +12 more
core +1 more source
USPs in Pancreatic Ductal Adenocarcinoma: A Comprehensive Bioinformatic Analysis of Expression, Prognostic Significance, and Immune Infiltration [PDF]
Yizhi Wang +5 more
openalex +1 more source
Clinical impact of duodenal pancreatic heterotopia – Is there a need for surgical treatment?
Background Pancreatic heterotopia (PH) is defined as ectopic pancreatic tissue outside the normal pancreas and its vasculature and duct system. Most frequently, PH is detected incidentally by histopathological examination.
Alexander Betzler +8 more
doaj +1 more source
Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model. [PDF]
Pancreatic ductal adenocarcinoma (PDAC) is a particularly deadly disease. Chronic conditions, including obesity and type-2 diabetes are risk factors, thus making PDAC amenable to preventive strategies.
Chang, Hui-Hua +10 more
core +2 more sources
Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies [PDF]
The first human monoclonal islet cell antibodies of the IgG class (MICA 1-6) obtained from an individual with Type 1 (insulin-dependent) diabetes mellitus were cytoplasmic islet cell antibodies selected by the indirect immunofluorescence test on pancreas
DJ Garry +19 more
core +1 more source
BRCA 1/2 Germline Mutation Predicts the Treatment Response of FOLFIRINOX with Pancreatic Ductal Adenocarcinoma in Korean Patients [PDF]
Ji Hoon Park +9 more
openalex +1 more source
Endoscopic ultrasound guided fine needle aspiration and endoscopic retrograde cholangiopancreatography guided biliary and pancreatic ductal brushings are being used as routine procedures to diagnose mass lesions of the pancreas and stenotic lesions of ...
Varsha Manucha, Oleh Haluszka
doaj +1 more source
RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis [PDF]
Tumor suppression that is mediated by oncogene-induced senescence (OIS) is considered to function as a safeguard during development of pancreatic ductal adenocarcinoma (PDAC). However, the mechanisms that regulate OIS in PDAC are poorly understood. Here,
Algül, Hana +17 more
core +1 more source

