Results 121 to 130 of about 439,784 (298)

Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways. [PDF]

open access: yesCell Metab, 2023
Basile G   +17 more
europepmc   +1 more source

Assessing the exercise‐related kinetics of circulating cell‐free DNA, circulating tumour DNA, DNase I activity and cytokines in patients with solid tumours: A pilot study

open access: yesExperimental Physiology, EarlyView.
Abstract Circulating cell‐free DNA (cfDNA), circulating tumour DNA (ctDNA) and inflammatory cytokines have prognostic and predictive value in oncology. However, the effects of acute exercise on cfDNA levels are unknown. Here, we explore the kinetics of cfDNA, ctDNA and cytokines upon an incremental exercise test in a pilot cohort of cancer patients ...
Elmo W. I. Neuberger   +10 more
wiley   +1 more source

Cellular Senescence in Cancer: Mechanisms, Roles in Tumor Progression, and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
Senescent tumor cells in TME exhibit dual roles. “Angels” secrete SASPs/DAMPs to boost immunological clearance and antitumor immunity via MHC‐I upregulation; “Demons” produce tumor‐promoting SASPs recruiting MDSCs to drive malignancy. ABSTRACT Cellular senescence, a state of irreversible cell cycle arrest accompanied by a senescence‐associated ...
Jingrui Yan   +5 more
wiley   +1 more source

Processing‐Driven Changes in Potato Protein‐Stabilized Emulsions and Their Digestibility: The Role of High‐Pressure Homogenization and Thermal Treatment

open access: yesSustainable Food Proteins, Volume 3, Issue 3, September 2025.
Process flow and summary of the experimental setup used to assess in vitro proteolysis and lipolysis of emulsions processed through high‐pressure homogenization and/or heat treatment. ABSTRACT This study investigates the digestibility of emulsions stabilized with potato protein isolate, focusing on how different processing conditions affect their ...
Luis Jiménez‐Munoz   +2 more
wiley   +1 more source

Pancreatic insufficiency in patients with HIV infection: role of didanosine questioned.

open access: yes, 2013
OBJECTIVES: The aim of the study was to identify possible causes of pancreatic insufficiency in patients with HIV infection. METHODS: A retrospective analysis of 233 HIV-positive patients for whom faecal elastase measurement was available was performed ...
Anastasi   +26 more
core   +1 more source

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