Results 51 to 60 of about 439,784 (298)

Safety evaluation of a food enzyme containing trypsin, chymotrypsin, elastase and carboxypeptidase from porcine pancreas

EFSA Journal, 2021
The food enzyme is a protease complex, containing trypsin (EC 3.4.21.4), chymotrypsin (EC 3.4.21.1), pancreatic elastase (EC 3.4.21.36) and carboxypeptidase B (EC 3.4.17.2), obtained from porcine pancreas by Neova Technologies Inc.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Vittorio Silano, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Claude Lambré, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Ursula Gundert‐Remy, Lieve Herman, Dominique Turck, Karl‐Heinz Engel, Margarita Aguilera‐Gómez, Magdalena Andryszkiewicz, Natalia Kovalkovicova, Yi Liu, Joaquim Maia, Sandra Rainieri, Andrew Chesson   +28 more
doaj   +1 more source

The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines [PDF]

, 2011
Supplementary to the efficient inhibition of trypsin, chymotrypsin, plasma kallikrein, and plasmin already described by the EcTI inhibitor from Enterolobium contortisiliquum, it also blocks human neutrophil elastase (K(iapp)=4.3 nM) and prevents phorbol ...
Bhoola K.D., Bjorklund M., Chao J.C., Dani R., Foekens J.A., Fritz H., Germanov E., Hildenbrand R., Kallakury B.V., Macedo M.L., Miyasaka M., Moll U.M., Ohkoshi M., Oliva M.L., Skrzydlewska E., Stanton H., Stearns M.   +16 more
core   +1 more source

Secondary exocrine pancreatic insufficiency. Features of the choice of the enzyme

Медицинский совет, 2021
Exocrine pancreatic insufficiency is quite common in clinical practice of doctors of many specialties. Decrease in intraduodenal lipase levels below 5–10% of normal leads to pancreatic steatorrhea, weight loss and a potential decrease in quality of life.
I. G. Pakhomova
doaj   +1 more source

Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.

Journal of Clinical Investigation, 2019
While improvements in genetic analysis have greatly enhanced our understanding of the mechanisms behind pancreatitis, it continues to afflict many families for whom the hereditary factors remain unknown.
Paul C. Moore, Jessica T. Cortez, C. Chamberlain, Diana L. Alba, A. Berger, Zoe Quandt, Alice Y. Chan, M. Cheng, J. Bautista, Justin Peng, M. German, Mark S. Anderson, Scott A Oakes   +12 more
semanticscholar   +1 more source

Accuracy of simultaneous measurement of serum biomarkers: Carbohydrate antigen 19-9, pancreatic elastase-1, amylase, and lipase for diagnosing pancreatic ductal adenocarcinoma

Journal of the Formosan Medical Association, 2022
Background: Pancreatic cancer is difficult to diagnose early since tumor markers have low sensitivity and specificity. We simultaneously measured serum carbohydrate antigen (CA) 19-9, pancreatic elastase-1, lipase, and amylase, and evaluated the accuracy
Chi-Ying Yang, Ro-Ting Lin, Chi-Yi Chen, Chun-Chieh Yeh, Chao-Ming Tseng, Wen-Hsin Huang, Teng-Yu Lee, Chia-Shen Chu, Jaw-Town Lin   +8 more
doaj  

Faecal elastase 1 in chronic pancreatitis [PDF]

Gut, 1999
Editor,—I read with interest the recent paper by Lankisch et al ( Gut 1998; 42 :551–4). The authors studied faecal elastase 1 and faecal chymotrypsin in 30 patients with chronic pancreatitis and concluded that the estimation of faecal elastase 1 is not helpful in diagnosing mild and moderate exocrine pancreatic insufficiency and that this enzyme is not
L GULLO, P G LANKISCH
openaire   +2 more sources

Prevalence of end-organ damage, beta cell reserve, and exocrine pancreas defect in fibrocalculous pancreatic diabetes: An Eastern India perspective

Indian Journal of Endocrinology and Metabolism, 2019
Background: Data on prevalence and burden of end-organ damage in fibrocalculous pancreatic diabetes (FCPD) from eastern India is scant. This study investigated the burden of end-organ damage and exocrine pancreatic defect in FCPD patients in Eastern ...
Beatrice Anne, Sujoy Ghosh, Ipsita Ghosh, Sayantan Ray, Subhankar Chowdhury, Deep Dutta   +5 more
doaj   +1 more source

Application of Human Type I Pancreatic Elastase (PRT-201) to the venous Anastomosis of Arteriovenous Grafts in Patients with Chronic Kidney Disease

Journal of Vascular Access, 2014
Purpose To explore the safety and efficacy of PRT-201 applied to the outflow vein of a newly created arteriovenous graft (AVG). Methods Randomized, double-blind, placebo-controlled, single-dose escalation study of PRT-201 (0.01 to 9 mg) applied to the ...
A. Dwivedi, P. Roy-Chaudhury, E. Peden, B. Browne, E. Ladenheim, V. Scavo, Pamela N. Gustafson, Marco D. Wong, M. Magill, Francesca Lindow, A. Blair, M. Jaff, F. N. Franano, S. Burke   +13 more
semanticscholar   +1 more source

Evaluation of Ionic Liquids and Ionic Liquids Active Pharmaceutical Ingredients Inhibition in Elastase Enzyme Activity

Molecules, 2021
Human neutrophil elastase (HNE) is used as diagnostic biomarker for inflammation/infection. In this work, 10 ionic liquids (ILs) and 11 ionic liquids active pharmaceutical ingredients (ILs-APIs) were tested to evaluate the inhibition effect on the ...
Fátima A. R. Mota, Sarah A. P. Pereira, André R. T. S. Araujo, M. Lúcia M. F. S. Saraiva   +3 more
doaj   +1 more source

Production of Secretory Leucocyte Protease Inhibitor (SLPI) in Human Pancreatic β-Cells

Mediators of Inflammation, 1999
Secretory leucocyte protease inhibitor (SLPI) is a potent inhibitor of granulocyte elastase and cathepsin G, and also an inhibitor of pancreatic enzymes like trypsin, chymotrypsin and pancreatic elastase.
Max Nyström, Magnus Bergenfeldt, Irena Ljungcrantz, Èsa Lindeheim, Kjell Ohlsson   +4 more
doaj   +1 more source