Results 1 to 10 of about 51,365 (299)

Pancreatic Enzyme Replacement Therapy in Patients Undergoing First-Line Gemcitabine Plus nab-paclitaxel for Advanced Pancreatic Adenocarcinoma [PDF]

Frontiers in Oncology, 2021
BackgroundThe clinical consequences of pancreatic exocrine insufficiency and its treatment in advanced pancreatic ductal adenocarcinoma (PDAC) are poorly investigated.
Ilaria Trestini, Luisa Carbognin, Luisa Carbognin, Umberto Peretti, Isabella Sperduti, Alberto Caldart, Daniela Tregnago, Alice Avancini, Alessandra Auriemma, Giulia Orsi, Sara Pilotto, Luca Frulloni, Gabriele Capurso, Emilio Bria, Michele Reni, Giampaolo Tortora, Michele Milella   +16 more
doaj   +2 more sources

Gut microbiome as a response marker for pancreatic enzyme replacement therapy in a porcine model of exocrine pancreas insufficiency [PDF]

Microbial Cell Factories, 2020
Background Exocrine pancreatic insufficiency (EPI) is characterized by the loss of active pancreatic enzymes and a resulting severely reduced food digestion. EPI therapy requires orally applied pancreatic enzyme replacement. The gut microbiome is a known
Sabrina Ritz, Daniela Hahn, Haleluya T. Wami, Karin Tegelkamp, Ulrich Dobrindt, Juergen Schnekenburger   +5 more
doaj   +2 more sources

Pancreatic enzyme replacement therapy can improve infection level nutrition condition and prognosis of patients with sepsis [PDF]

Food & Nutrition Research
Objective: This study aimed to investigate the effects of pancreatic enzyme replacement therapy (PERT) on infection level, nutrition condition and prognosis of patients with sepsis.
Li Zhao, Sheng Wang
doaj   +2 more sources

Pancreatic Enzyme Replacement Therapy in hyperglycemic Male Rats

Kufa Journal for Veterinary Medical Sciences, 2020
The study was designed to evaluated exocrine pancreatic enzyme replacement therapy in hyperglycemic male rats induced by alloxan. A total of forty five adult male rats were use in this study, hyperglycemia was induce in thirty rats by single ...
Muhammad Ali Hameed Jalil, Nabeel M. N. Al-Sharafi   +1 more
doaj   +2 more sources

Pancreatic enzyme replacement therapy in subjects with exocrine pancreatic insufficiency and diabetes mellitus: a real-life, case–control study [PDF]

Diabetology & Metabolic Syndrome
Background Exocrine pancreatic insufficiency (EPI) can be associated with all types of diabetes. Pancreatic enzyme replacement therapy (PERT) has short and long-term benefits in subjects with EPI, but its effects on diabetes control are uncertain.
Laure Alexandre-Heymann, Fetta Yaker, Pierre Bel Lassen, Danièle Dubois-Laforgue, Etienne Larger   +4 more
doaj   +2 more sources

The effectiveness of pancreatic enzyme replacement therapy for malabsorption in advanced pancreatic cancer, a pilot study [PDF]

Palliative Care, 2019
Advanced adenocarcinoma of the pancreas has a globally poor prognosis. One of the characteristic features of pancreatic cancer (PC) is pancreatic exocrine insufficiency (PEI).
Amanda Landers, Helen Brown, Matthew Strother   +2 more
doaj   +2 more sources

Current and Future Therapeutic Approaches of Exocrine Pancreatic Insufficiency in Children with Cystic Fibrosis in the Era of Personalized Medicine

Pharmaceutics, 2023
This review presents current updates of pancreatic enzyme replacement therapy in children with cystic fibrosis based on literature published in the last decade and some special considerations regarding pancreatic enzyme replacement therapy in the era of ...
Mirela-Elena Ritivoiu, Cristina Manuela Drăgoi, Dumitru Matei, Iustina Violeta Stan, Alina Crenguţa Nicolae, Mihai Craiu, Ion-Bogdan Dumitrescu, Alina Angelica Ciolpan   +7 more
doaj   +1 more source

AGA-PancreasFest Joint Symposium on Exocrine Pancreatic Insufficiency

Gastro Hep Advances, 2023
Exocrine pancreatic insufficiency (EPI) is a clinically defined syndrome based on the physician’s assessment of a patient’s maldigestion. However, current clinical definitions are inadequate in determining (1) the threshold of reduced pancreatic ...
David C. Whitcomb, Sinead N. Duggan, Robert Martindale, Mark Lowe, Virginia A. Stallings, Darwin Conwell, Jodie A. Barkin, Georgios I. Papachristou, Sohail Z. Husain, Christopher E. Forsmark, Vivek Kaul   +10 more
doaj   +1 more source

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

Management of chronic pancreatitis

Apollo Medicine, 2021
Chronic pancreatitis is a chronic inflammatory disorder in which irreversible changes result in fibrosis leading to endocrine and exocrine insufficiency.
Manu Tandan, Mahiboob Sayyed
doaj   +1 more source