Results 71 to 80 of about 1,457,192 (230)

Multidisciplinary treatment of pancreatic neuroendocrine neoplasm with portal vein thrombosis and multiple liver metastases by minimally invasive surgical and neoadjuvant therapy

Journal of Pancreatology
The treatment of patients with pancreatic neuroendocrine neoplasms accompanied by metastasis is complex and highly individualized. This article reports a 43-year-old male patient diagnosed with a neuroendocrine tumor on the pancreatic tail combined with ...
Hao Chen, Wenhao Luo, Xianze Wang, Zhe Cao, Xianlin Han   +4 more
doaj   +1 more source

Pancreatic neuroendocrine tumours: a comparison of cytological classification systems. [PDF]

Aims: Cytological classification systems provide a standardised interpretation framework for reporting cytological specimens. Three well-known classification systems can be applied when reporting pancreatic cytology.
Hanks, Matthew, Zaitoun, Abed M, Sajid, Saira, Lobo, Dileep N, Bancu, Andrei, Khan, Marium, Ackroyd, Lauren   +6 more
core   +1 more source

Identification of pancreatic cancer invasion-related proteins by proteomic analysis [PDF]

, 2009
Background – Markers of pancreatic cancer invasion were investigated in two clonal populations of the cell line, MiaPaCa-2, Clone #3 (high invasion) and Clone #8 (low invasion) using proteomic profiling of an in vitro model of pancreatic cancer ...
Naomi Walsh, Walsh Naomi, Martin Clynes, Meleady Paula, Henry Michael, Clynes, Martin, Kennedy Susan, Susan Kennedy, O'Donovan, Norma, Clynes Martin, Michael Henry, Walsh, Naomi, Dowling, Paul, Paula Meleady, O'Donovan Norma, Meleady, Paula, Norma O'Donovan, Kennedy, Susan, O\u27Donovan, Norma, Henry, Michael, Dowling Paul, Paul Dowling   +21 more
core   +2 more sources

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Gastric mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) with pancreatic acinar differentiation: a case report

Diagnostic Pathology, 2019
Background Gastric mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) are infrequently encountered in routine practice. Some gastric neuroendocrine carcinomas (NECs) have a variety of differentiation patterns; however, pancreatic acinar ...
Yasuko Fujita, Noriyuki Uesugi, Ryo Sugimoto, Makoto Eizuka, Takayuki Matsumoto, Tamotsu Sugai   +5 more
doaj   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

A RARE CLINICAL CASE OF MIXED SEROUS NEUROENDOCRINE CYSTIC NEOPLASM OF THE PANCREAS

Сибирский онкологический журнал, 2018
Background. Serous cystic pancreatic neoplasm is a rare pancreatic tumor, accounting for 1–2 % of all pancreatic tumors. In 2010,  mixed serous neuroendocrine cystic neoplasia was included into the classification of the WHO for pancreatic tumors.
A. P. Koshel, V. V. Alipov, L. R. Bazilevich, A. I. Khvashchevsky, I. L. Purlik, E. S. Drozdov   +5 more
doaj   +1 more source

Molecular drivers and cells of origin in pancreatic ductal adenocarcinoma and pancreatic neuroendocrine carcinoma

Experimental Hematology & Oncology, 2020
Pancreatic cancer is one of the most common causes of cancer-related deaths worldwide. The two major histological subtypes of pancreatic cancer are pancreatic ductal adenocarcinoma (PDAC), accounting for 90% of all cases, and pancreatic neuroendocrine ...
He-Li Gao, Wen-Quan Wang, Xian-Jun Yu, Liang Liu   +3 more
doaj   +1 more source

NKX6-1 Is a Novel Immunohistochemical Marker for Pancreatic and Duodenal Neuroendocrine Tumors

, 2017
NKX6-1 is a homeobox transcription factor participating in the development and regulation of endocrine function of pancreatic islets. This study evaluated the potential use of NKX6-1 as a diagnostic marker for well-differentiated neuroendocrine tumors ...
Tseng, I-Ching;Yeh, Matthew M.;Yang, Ching-Yao;Jeng, Yung-Ming, 鄭永銘;楊卿堯   +1 more
core   +1 more source