Results 101 to 110 of about 1,842,584 (317)
SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways
Advanced Science, EarlyView.In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao +5 morewiley +1 more sourceEfficacy and Safety Analysis of Transarterial Chemoembolization Combined with Sintilimab Plus Bevacizumab Biosimilar in the Treatment of Unresectable Hepatocellular Carcinoma
Journal of Hepatocellular CarcinomaHuixia Qin,1,* Kaiwen Jiang,2,* Chengyuan Liu,2,* Hesheng Lin,2,* Jing Xia,2,* Houxiang Ya,2 Jing Gu,2 Liya Suo,2 Bo Li,2 Xin Deng,2 Dejie Wang,3 Xiaowang Huang,3 Shuqun Li2 1Interventional Center, The First ...Qin H, Jiang K, Liu C, Lin H, Xia J, Ya H, Gu J, Suo L, Li B, Deng X, Wang D, Huang X, Li S +12 moredoaj The Daily Practice of Pancreatic Enzyme Replacement Therapy After Pancreatic Surgery: A Northern European Survey: Enzyme Replacement After Surgery [PDF]
, 2012 Introduction: After pancreatic surgery, up to 80 % of patients will develop exocrine insufficiency. For enzyme supplementation to be effective, prescribing an adequate dose of pancreatic enzymes is mandatory but challenging because the required dose ...Djuna L. Cahen, Cahen, Djuna, van Eijck, Casper, Bruno, Marco, Cahen, D.L. (Djuna), Sikkens, Edmee, Kuipers, Ernst, Eijck, C.H.J. (Casper) van, Ernst J. Kuipers, Sikkens, E.C.M. (Edmée), Edmée C. M. Sikkens, Bruno, M.J. (Marco), Marco J. Bruno, Kuipers, E.J. (Ernst), Casper van Eijck +14 morecore +2 more sourcesConsensus Statement on the Use of Near-Infrared Fluorescence Imaging during Pancreatic Cancer Surgery Based on a Delphi Study: Surgeons’ Perspectives on Current Use and Future Recommendations
, 2023 Simple Summary
Despite the potential of fluorescence imaging during pancreatic cancer surgery, more research is needed to facilitate the approval of tumor-targeted probes, standardize imaging techniques, and most importantly, gain trust from ...Rangelova, Elena, Boni, Luigi, White, Kevin P., Boni, Luigi; 6Department of Surgery, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico di Milano, 20122 Milano, Italy, Ishizawa, Takeaki, Gockel, Ines; 11Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, 04103 Leipzig, Germany, Bannone, Elisa; 4Department of General and Pancreatic Surgery, The Pancreas Institute, 37134 Verona, Italy, Fuchs, Hans F.; 9Department of Surgery, University of Cologne, 50923 Köln, Germany, Nickel, Felix; 12Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, 69120 Heidelberg, Germany, Bouvet, Michael, Falconi, Massimo, Rosenthal, Raul J.; 19Cleveland Clinic Florida, Weston, FL 33331, USA, de Muynck, Lysanne D. A. N., Hackert, Thilo, Bouvet, Michael; 7Department of Surgery, University of California, San Diego, CA 92093, USA, Kang, Chang Moo, Alseidi, Adnan; 3Department of Surgery, University of California, San Francisco, CA 94143, USA, Gockel, Ines, Nickel, Felix, Rangelova, Elena; 16Department of Upper Abdominal Surgery, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden, Dip, Fernando, Kokudo, Norihiro, Vahrmeijer, Alexander L.; 1Department of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands, Bannone, Elisa, Fuchs, Hans F., de Muynck, Lysanne D. A. N.; 1Department of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands, Swijnenburg, Rutger Jan; 18Department of Surgery, Amsterdam University Medical Center—Location AMC, 1105 AZ Amsterdam, The Netherlands, White, Kevin P.; 2ScienceRight Research Consulting, London, ON N6A 3S9, Canada, Ishizawa, Takeaki; 13Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8654, Japan, Mieog, J. Sven D.; 1Department of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands, Kang, Chang Moo; 14Department of Hepatobiliary and Pancreatic Surgery, Yonsei University College of Medicine, Seoul 03722, Republic of Korea, Kokudo, Norihiro; 15National Center for Global Health and Medicine, Tokyo 162-8655, Japan, Rosenthal, Raul J., Vahrmeijer, Alexander L., Ghadimi, Michael; 10Department of General, Visceral and Pediatric Surgery, University of Göttingen, 37075 Goettingen, Germany, Falconi, Massimo; 8Pancreas Translational & Clinical Research Center, Vita-Salute San Raffaele University, 20132 Milan, Italy, Alseidi, Adnan, Swijnenburg, Rutger Jan, Hackert, Thilo; 12Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, 69120 Heidelberg, Germany, Ghadimi, Michael, Partelli, Stefano, Mieog, J. Sven D., Partelli, Stefano; 8Pancreas Translational & Clinical Research Center, Vita-Salute San Raffaele University, 20132 Milan, Italy, Dip, Fernando; 19Cleveland Clinic Florida, Weston, FL 33331, USA +43 morecore +1 more sourceReview of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics
Advanced Science, EarlyView.This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun +8 morewiley +1 more sourceDetrimental and Beneficial Diets Regulate Acute Pancreatitis Through Convergent Gut Microbiota Pathways
Journal of Inflammation ResearchJiafu Wu,1,2,* Rui Bai,1,2,* Zehua Zhong,1,* Can Zhang,1,2,* Tianqi Liu,1,2 Tianqi Lu,1,2 Yiqin Song,1,2 Zhihan Miao,1 Duoyi Zhang,1 Ziqi Wang,1 Guanqun Li,1,2 Bei Sun1,21Department of Pancreatic and Biliary Surgery, The ...Wu J, Bai R, Zhong Z, Zhang C, Liu T, Lu T, Song Y, Miao Z, Zhang D, Wang Z, Li G, Sun B +11 moredoaj A root-cause analysis of mortality following major pancreatectomy
, 2012 Introduction: Although mortality rates from pancreatectomy have decreased worldwide, death remains an infrequent but profound event at an individual practice level.Sanchez N, Christein JD, Gondek S, Callery MP, Marchegiani G, McAuliffe J, of Pancreatic Surgery Mortality Study Group, Vollmer CM Jr, Kent TS +8 morecore +1 more sourceRGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis
Advanced Science, EarlyView.RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...Xinglong Li, Zhanzhi Meng, Hongjun Yu, Yongliang Hua, Zihao Li, Bing Yin, Baolin Qian, Zhongyu Li, Yongzhi Zhou, Zhigang Feng, Shounan Lu, Shanjia Ke, Miaoyu Bai, Yao Fu, Wei Tang, Natalia V. Belosludtseva, Yong Ma +16 morewiley +1 more sourcePostoperative Adjuvant Transcatheterarterial Chemoembolization Should Be Considered Selectively for Patients with Cytokeratin-19 Positive Hepatocellular Carcinoma
Journal of Hepatocellular CarcinomaRong-Yun Mai,1,* Zheng Tao,1,* Hong-Yang Huang,1,* Can Zeng,1 Kai-Xiang Mo,1 Dan-Dan Zeng,2 Rong Liang,2 Yan Lin,2 Xiao-Bo Wang,1 Tao Bai,1 Le-Qun Li,1 Jia-Zhou Ye,1 Guo-Bin Wu1 1Department of Hepatobiliary & Pancreatic ...Mai RY, Tao Z, Huang HY, Zeng C, Mo KX, Zeng DD, Liang R, Lin Y, Wang XB, Bai T, Li LQ, Ye JZ, Wu GB +12 moredoaj
