Results 111 to 120 of about 1,842,584 (317)

Laparoscopic Middle Pancreatectomy under a Pancreatic Duct-Navigation Surgery [PDF]

, 2012
Recent developments of diagnostic modalities have increased detection of many benign and low malignant pancreatic lesions, and then various minimally invasive surgeries and/or pancreatic function preserving surgeries have been devised for such lesions ...
Adachi, Tomohiko, Kitasato, Amane, Tajima, Yoshitsugu, Kuroki, Tamotsu, Inokuma, Takamitsu, Kanematsu, Takashi   +5 more
core   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Predictive Value of Hepatic Steatosis for Postoperative Recurrence in Hepatitis B-Related Hepatocellular Carcinoma: Development of a Machine Learning-Based Prognostic Model

Journal of Hepatocellular Carcinoma
Aoyun Hao, Changlei Li, Ruitao Sun, Bin Tan, Guanming Shao, Kun Li, Na Li, Weiyu Hu, Chao Qu, Jingyu Cao Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of ...
Hao A, Li C, Sun R, Tan B, Shao G, Li K, Li N, Hu W, Qu C, Cao J   +9 more
doaj  

Role of common bile duct resection in T2 and T3 gallbladder cancer patients [PDF]

, 2018
Backgrounds/Aims: Routine bile duct resection as part of the typical oncological resection for patients with advanced gallbladder cancer remains controversial with regard to, ultimately, curative value.
정재욱, 김경식, 박승우, 최진섭, 임진홍, 이우정   +5 more
core   +1 more source

Hypomethylation of GNA15 Promotes Pancreatic Ductal Adenocarcinoma Progression and Macrophage M2 Polarization via STAT3‐CXCL8 Axis

Advanced Science, EarlyView.
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo, Zhenyuan Qian, Lei Wang, Weilang Xu, Yuxin Weng, Kai Jiang, Zaiyuan Ye, Ji Xu, Guangyuan Song   +8 more
wiley   +1 more source

Stress-Induced Hyperglycemia as an Independent Predictor of Infectious Pancreatic Necrosis in Acute Pancreatitis: A Machine Learning-Driven Prognostic Model

Journal of Inflammation Research
Xuchen Zhao,1,* Jiale Xu,2,* Congzhong Hu,1,* Wei Xue,1 Zongyuan Che,1 Ruiqi Ling,1 Haoyang Chen,1 Yulin Feng,1 Xiaolong Li,1 Shaojian Mo,1 Yanzhang Tian1 1Department of Biliary and Pancreatic Surgery, The Third Hospital of Shanxi
Zhao X, Xu J, Hu C, Xue W, Che Z, Ling R, Chen H, Feng Y, Li X, Mo S, Tian Y   +10 more
doaj  

The effects of systemic inflammatory response on prognosis of pancreatic ductal adenocarcinoma

, 2019
Backgrounds/Aims: The aim of this study was to investigate the prognostic significance of neutrophyil-lymphocyte ratio (NLR), platelet- lymphocyte ratio (PLR), CRP and CA19-9 in patients were diagnosed with pancreatic ductal adenocarcinoma (PDAC) to ...
Aktekin, Ali, Torun, Mehmet, Müftüoǧlu, Tolga Munip Ali, Özkara, Selvinaz, Öven, Bala Başak, Cakır, Özcan   +5 more
core   +1 more source

A Single‐Amino‐Acid Ligand for LAT1: A Minimalist and Modular Platform for Lysosome‐Targeted Degradation of Membrane Proteins

Advanced Science, EarlyView.
LA‐LYTAC repurposes the cancer‐enriched amino acid transporter LAT1 as a lysosomal trafficking receptor for targeted membrane‐protein degradation. A single phenylalanine‐derived ligand, modularly linked to antibodies or small‐molecule binders, recruits PD‐L1, EGFR, or integrins to LAT1, triggering transporter‐mediated internalization, lysosomal ...
Liquan Zhu, Ke Liu, Haotian Liu, Chaoqi He, Xiaozhen Liu, Xin Zeng, Misha Mao, Yuxiao Mu, Ying Li, Qinghui Zheng, Hongchao Tang, Da Qian, Xuli Meng   +12 more
wiley   +1 more source

Prognostic Value of the SEA Score in Double-Negative DCP/AFP Unresectable HCC with Triple Therapy

Journal of Hepatocellular Carcinoma
Hesheng Lin,1,* Fulin Ran,2,* Jiayi Wu,3,* Chaoyue Huang,2,* Junyi Wu,3,* Chengyuan Liu,1 Xueyao Wang,4 Houxiang Ya,1 Kaiwen Jiang,1 Jing Gu,1 Maolin Yan,3 Shuqun Li1 1Department of Hepatobiliary and Pancreatic ...
Lin H, Ran F, Wu J, Huang C, Wu J, Liu C, Wang X, Ya H, Jiang K, Gu J, Yan M, Li S   +11 more
doaj  

Extracellular vesicles from chemotherapy-induced senescent tumor cells reprogram hepatic phospholipid metabolism to promote pancreatic cancer liver metastasis

Journal of Experimental & Clinical Cancer Research
Background Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease, with over one-third of patients developing liver metastasis following neoadjuvant chemotherapy (NAC). This study aimed to investigate how the effect of chemotherapy on the
Bai’an Tao, Yecheng Xu, Wenteng Miao, Zhenmei Chen, Jichun Gu, Yujie Guo, Linjie Chen, Yang Di, Hang He, Chen Jin, Ji Li, Deliang Fu   +11 more
doaj   +1 more source