Results 81 to 90 of about 451,958 (353)
Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models. [PDF]
, 2016 The goal of the present study was to determine whether insulin-like growth factor-1 receptor (IGF-1R) antibodies, conjugated with bright fluorophores, could enable visualization of pancreatic cancer in orthotopic nude mouse models. IGF-1R antibody (clone
Bouvet, Michael +4 more
core +2 more sources
Role of magnetic resonance imaging in the detection and characterization of solid pancreatic nodules: an update [PDF]
, 2015 Pancreatic ductal adenocarcinoma is the most common malignant tumor of the pancreas. The remaining pancreatic tumors are a diverse group of pancreatic neoplasms that comprises cystic pancreatic neoplasms, endocrine tumors and other uncommon pancreatic ...
Ansari, Najwa Al +5 more
core +1 more source
Molecular alterations in pancreatic tumors
World Journal of Gastroenterology, 2021 Genetic alterations in pancreatic tumors can usually be classified in: (1) Mutational activation of oncogenes; (2) Inactivation of tumor suppressor genes; and (3) Inactivation of genome maintenance genes controlling the repair of DNA damage. Endoscopic ultrasound-guided fine-needle aspiration has improved pre-operative diagnosis, but the management of ...
Visani M. +14 more
openaire +2 more sources
Genomic landscape and preclinical models of angiosarcoma
Molecular Oncology, EarlyView.Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton +3 more
wiley +1 more source
A Novel Framework for Characterization of Tumor-Immune Spatial Relationships in Tumor Microenvironment [PDF]
arXiv, 2022 Understanding the impact of tumor biology on the composition of nearby cells often requires characterizing the impact of biologically distinct tumor regions. Biomarkers have been developed to label biologically distinct tumor regions, but challenges arise because of differences in the spatial extent and distribution of differentially labeled regions ...
arxiv
Attenuation of hedgehog/GLI signaling by NT1721 extends survival in pancreatic cancer. [PDF]
, 2019 BackgroundPancreatic cancer is one of the most lethal malignancies due to frequent late diagnosis, aggressive tumor growth and metastasis formation.
Horne, David A +4 more
core +1 more source
Reshaping the tumor stroma for treatment of pancreatic cancer [PDF]
, 2018 Pancreatic cancer is accompanied by a fibrotic reaction that alters interactions between tumor cells and the stroma to promote tumor progression. Consequently, strategies to target the tumor stroma might be used to treat patients with pancreatic cancer ...
Cox, Thomas R. +5 more
core +1 more source
Autoimmune pancreatitis mimicking pancreatic tumor [PDF]
Journal of Surgical Case Reports, 2012 Autoimmune pancreatitis (AIP) is a rare disease of unknown pathomechanism. It belongs to the IgG4-related disease family and responds well to steroids, although the relapse rate can reach up to 20–30%. Differentiating AIP from the more common pancreatic cancer can be very challenging.
Ferenc Salamon +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang +3 more
wiley +1 more source
A Novel and Efficient Tumor Detection Framework for Pancreatic Cancer via CT Images [PDF]
arXiv, 2020 As Deep Convolutional Neural Networks (DCNNs) have shown robust performance and results in medical image analysis, a number of deep-learning-based tumor detection methods were developed in recent years. Nowadays, the automatic detection of pancreatic tumors using contrast-enhanced Computed Tomography (CT) is widely applied for the diagnosis and staging
arxiv