Results 41 to 50 of about 7,055 (209)
Connexin43 hemichannels in satellite glial cells, can they influence sensory neuron activity? [PDF]
Indexación: Scopus.In this review article, we summarize the current insight on the role of Connexin- and Pannexin-based channels as modulators of sensory neurons.
Alcayaga, J. +3 more
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Temperature-dependent release of ATP from human erythrocytes: Mechanism for the control of local tissue perfusion [PDF]
Copyright @ 2012 The AuthorsThis article has been made available through the Brunel Open Access Publishing Fund.Human limb muscle and skin blood flow increases significantly with elevations in temperature, possibly through physiological processes that ...
Abraham +58 more
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Pannexin Channel Inhibition [PDF]
More than 50 years after spironolactone has come on the market its mechanism of action continues to expand. In this issue of Circulation Research , Good et al1 document the discovery that spironolactone is not only an inhibitor of the mineralocorticoid receptor but also inhibits pannexin 1 channels.
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Background: Accumulating evidence suggests that neuroinflammation plays a critical role in early brain injury after subarachnoid hemorrhage (SAH). Pannexin-1 channels, as a member of gap junction proteins located on the plasma membrane, releases ATP ...
Ling-Yun Wu +13 more
doaj +1 more source
Connexin36 knockout mice display increased sensitivity to pentylenetetrazol-induced seizure-like behaviors [PDF]
Large-scale synchronous firing of neurons during seizures is modulated by electrotonic coupling between neurons via gap junctions. To explore roles for connexin36 (Cx36) gap junctions in seizures, we examined the seizure threshold of connexin36 knockout (
Cursons, Raymond T. +7 more
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Pannexin 1 and Pannexin 3 Channels Regulate Skeletal Muscle Myoblast Proliferation and Differentiation [PDF]
Pannexins constitute a family of three glycoproteins (Panx1, -2, and -3) forming single membrane channels. Recent work demonstrated that Panx1 is expressed in skeletal muscle and involved in the potentiation of contraction. However, Panxs functions in skeletal muscle cell differentiation, and proliferation had yet to be assessed.
Langlois, Stéphanie +5 more
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Pannexin1 stabilizes synaptic plasticity and is needed for learning. [PDF]
Pannexin 1 (Panx1) represents a class of vertebrate membrane channels, bearing significant sequence homology with the invertebrate gap junction proteins, the innexins and more distant similarities in the membrane topologies and pharmacological ...
Nora Prochnow +10 more
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The biochemistry and function of pannexin channels
Three family members compose the pannexin family of channel-forming glycoproteins (Panx1, Panx2 and Panx3). Their primary function is defined by their capacity to form single-membrane channels that are regulated by post-translational modifications, channel intermixing, and sub-cellular expression profiles.
Penuela, Silvia +2 more
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Synaptic signaling complexes are held together by scaffold proteins, each of which is selectively capable of interacting with a number of other proteins.
Alejandro Vila +9 more
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Kinetics of extracellular ATP in mastoparan 7-activated human erythrocytes [PDF]
Background: The peptide mastoparan 7 (MST7) stimulated ATP release in human erythrocytes. We explored intraand extracellular processes governing the time-dependent accumulation of extracellular ATP (i.e., ATPe kinetics).
Espelt, Maria Victoria +6 more
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