Results 141 to 150 of about 2,639 (160)

Synthesis of 3-Carboxy-6-sulfamoylquinolones and Mefloquine-Based Compounds as Panx1 Blockers: Molecular Docking, Electrophysiological and Cell Culture Studies. [PDF]

Molecules
Crocetti L, Giovannoni MP, Pavlov TS, Ivanov V, Melani F, Guerrini G.   +5 more
europepmc   +1 more source

Microglial Panx1 as a therapeutic target for opioid withdrawal

, 2020
openaire   +1 more source

DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma. [PDF]

Front Immunol
Wu Q, Xiao Q, Tang X, Li L, Song D, Zhou Y, Li B, Ren G, Luo F.   +8 more
europepmc   +1 more source

The Multifaceted Role of P2X7R in Microglia and Astrocytes. [PDF]

Neurochem Res
Bedetta M, Pizzo P, Lia A.
europepmc   +1 more source

Novel Naphthyridones Targeting Pannexin 1 for Colitis Management. [PDF]

Adv Sci (Weinh)
Hsueh WY, Wu YL, Weng MT, Liu SY, Santavanond JP, Liu YC, Lin CI, Lai CN, Lu YR, Hsu JY, Gao HY, Lee JC, Wei SC, Lyu PC, Poon IKH, Hsieh HP, Chiu YH.   +16 more
europepmc   +1 more source

Connexin 43 and Pannexin 1 hemichannels as endogenous regulators of innate immunity in sepsis. [PDF]

Front Immunol
Li J, Lou L, Chen W, Qiang X, Zhu C, Wang H.   +5 more
europepmc   +1 more source

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Spreading Depression Triggers Headache by Activating Neuronal Panx1 Channels

Science, 2013
How Migraine Develops Migraine is a common medical disorder. Unfortunately, how and why migraine headache is initiated is unclear. Karatas et al. (p. 1092 ) now describe
Hulya, Karatas, Sefik Evren, Erdener, Yasemin, Gursoy-Ozdemir, Sevda, Lule, Emine, Eren-Koçak, Zümrüt Duygu, Sen, Turgay, Dalkara   +6 more
openaire   +2 more sources

Homozygous variants in PANX1 cause human oocyte death and female infertility

European Journal of Human Genetics, 2021
PANX1, one of the members of the pannexin family, is a highly glycosylated channel-forming protein. Recently, we identified heterozygous variants in PANX1 that follow an autosomal dominant inheritance pattern and cause female infertility characterized by oocyte death. In this study, we screened for novel PANX1 variants in patients with the phenotype of
Weijie Wang, Ronggui Qu, Qian Dou, Fengyan Wu, Wenjing Wang, Biaobang Chen, Jian Mu, Zhihua Zhang, Lin Zhao, Zhou Zhou, Jie Dong, Yang Zeng, Ruyi Liu, Jing Du, Shujia Zhu, Qiaoli Li, Lin He, Li Jin, Lei Wang, Qing Sang   +19 more
openaire   +2 more sources