Results 121 to 130 of about 3,650 (196)

The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity

Cell Death & Disease
AbstractDiscovery of new small molecules that can activate distinct programmed cell death pathway is of significant interest as a research tool and for the development of novel therapeutics for pathological conditions such as cancer and infectious diseases.
Jascinta P. Santavanond, Yu-Hsin Chiu, Rochelle Tixeira, Zonghan Liu, Jeremy K. Y. Yap, Kaiwen W. Chen, Chen-Lu Li, Yi-Ru Lu, Joan Roncero-Carol, Esteban Hoijman, Stephanie F. Rutter, Bo Shi, Gemma F. Ryan, Amy L. Hodge, Sarah Caruso, Amy A. Baxter, Dilara C. Ozkocak, Chad Johnson, Zoe I. Day, Alyce J. Mayfosh, Mark D. Hulett, Thanh K. Phan, Georgia K. Atkin-Smith, Ivan K. H. Poon   +23 more
openaire   +8 more sources

Deficient IL-1β release from activated Panx1 KO splenic macrophages.

, 2013
Bar histograms showing the mean ± s.e.m. values of interleukin-1β (IL-1β) measured from media bathing Panx1 wild type (WT) and Panx1 knockout (KO) macrophage cultures that were untreated, treated with lipopolysaccharide (LPS) and treated with LPS and ...
Sylvia O. Suadicani (424633), Leonid Tarassishin (326809), Juan Carlos Chara Ventura (424630), Naman K. Patel (204869), Sarah E. Lutz (204871), Hiromitsu Negoro (424632), Sunhee C. Lee (326811), Carlos Matute (201313), Eliana Scemes (204874), Estibaliz González-Fernández (424629), Alberto Pérez-Samartín (424631)   +10 more
core   +1 more source

Role of panx1 in bone marrow-derived macrophages and possible links to atherosclerosis

, 2017
Aim: Atherosclerosis is a major cardiovascular disease and the principal cause of death worldwide. It is a progressive disease of the medium-sized and large arties characterized by a dysfunctional endothelium, an accumulation of lipids and an abnormal ...
Ehrlich, Avigail
core   +1 more source

BDNF-TrkB Signaling Engages a Src Family Kinase-Pannexin 1 Pathway During the Onset of Sustained Mechanical Hyperalgesia. [PDF]

Int J Mol Sci
Aránguiz Barrera J, Moreira-Banuth AM, Zepeda-Morales K, Triolo M, Oneto NI, Bravo D, Huidobro-Toro JP, Donoso MV, Noseda R, Pelissier T, Hernández A, Constandil L, Retamal JS.   +12 more
europepmc   +1 more source

Machine learning prioritization identifies PANX1 as an inflammation-associated candidate regulator in lung adenocarcinoma. [PDF]

Front Genet
Yang Y, Fan T, Miao X, Ren C.
europepmc   +1 more source

Circulating PANX1, P2RY2, and TLR3 Profiles in Gastric Cancer: A Preliminary Molecular Study. [PDF]

Int J Mol Sci
Genc HC, Zontul C, Agbektas T, Kabak G, Tas A.   +4 more
europepmc   +1 more source

Investigating macropinocytosis as the mechanism of ATP-induced PANX1 internalization in Neuro2a cells [PDF]

The widely expressed pannexin 1 (PANX1) ion and metabolite channel, facilitates the release of ATP release for downstream signaling, and in turn, is regulated by extracellular ATP concentrations.
You, Haifei
core  

Additional file 1 of Neuronal Panx1 drives peripheral sensitization in experimental plantar inflammatory pain

Additional file 1: Table S1 Primer pairs for qRT-PCR. Fig. S1 Detailed pain threshold analysis in WT, global Panx1 KO, NFH-Cre, and GFAP-Cre Panx1 KO mice after CFA inflammation. Fig.
Preeti Dohare (17655559), Greta Luyuan Yang (8628687), David C. Spray (294210), Qing-Hua Li (1633066), Antonio Cibelli (8847641), Eliana Scemes (204874), Qu Xing (18464472), Fang-Xia Guan (18464475)   +7 more
core   +1 more source

Reduced Serum Pannexin-1 Levels in Obstructive Sleep Apnea and Their Association with Nocturnal Hypoxemic Burden. [PDF]

J Clin Med
Canlı ET, Öztürk Ö, Türkmen Kaya H, Şirin FB, Gümüşcan D, Aydın T, Karaibrahimoğlu A.   +6 more
europepmc   +1 more source

Altered Circulating Biomarkers of Purinergic Signaling, Inflammasome-Related Pathways, Pyroptosis, and Oxidative Stress in Fibromyalgia. [PDF]

Int J Mol Sci
Hayta E, Agbektas T, Kabak G, Dogan G, Tas A, Silig Y.   +5 more
europepmc   +1 more source