Results 181 to 190 of about 3,413 (197)
Some of the next articles are maybe not open access.
Sleep-wake cycle and experimental models of Panx1 mutations
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2018To test the hypothesis of a possible role of the Panx1 (pannexin-1) mutation in changing the sleep - wake cycle.Continuous 24 h recording of the EEG and movement activity in Panx1 knockout and wild type mice was performed.A significant increase in wake percentage at the expense of a decrease in slow-wave sleep was found in knockout mice as compared to ...
V M, Kovalzon +3 more
openaire +2 more sources
Cardiomyocyte PANX1 Controls Glycolysis and Neutrophil Recruitment in Hypertrophy
Circulation ResearchBACKGROUND: PANX1 (pannexin 1), a ubiquitously expressed ATP release membrane channel, has been shown to play a role in inflammation, blood pressure regulation, and myocardial infarction. However, the possible role of PANX1 in cardiomyocytes in the progression of heart failure has not yet been investigated.
Cm Pavelec +2 more
exaly +3 more sources
[Distribution and regulation of Panx1 protein].
Sheng li ke xue jin zhan [Progress in physiology], 2014Pannexin1 (Panx1) is a subtype of the newly discovered gap junction proteins named Pannexin(s). Panx1 is widely expressed in the nervous system, cardiovascular system, etc and can form non-selective and large conductance hemichannel. It has been demonstrated that various conditions can regulate Panx1 open and affect the body's physiological function ...
Xiang-Xing, Kong +3 more
openaire +1 more source
Spreading Depression Triggers Headache by Activating Neuronal Panx1 Channels
Science, 2013How Migraine Develops Migraine is a common medical disorder. Unfortunately, how and why migraine headache is initiated is unclear. Karatas et al. (p. 1092 ) now describe
Hulya, Karatas +6 more
openaire +2 more sources
The Sleep–Waking Cycle and Experimental Models of Mutations in the Panx1 Gene
Neuroscience and Behavioral Physiology, 2019Objectives. To confirm the authors’ previous suggestion that mutations in the Panx1 gene (pannexin-1) may play an important role in the development of impairments to the sleep-waking cycle. Materials and methods. Studies were carried out using mice with knockout of the Panx1 gene.
V M Kovalzon, Kovalzon V M
exaly +2 more sources
Panx1 as a potential therapeutic target for cardiac ischemia/reperfusion injury
2022Cardiovascular disease (CVD) is recognized as a major cause of death worldwide. Restriction of the blood supply leads to detrimental effects within the myocardium, which are paradoxically exacerbated upon reperfusion. Few therapeutic strategies are available up to date, yet none of the treatment is efficient enough to abolish ischemia/reperfusion (I/R)
openaire +1 more source
Conformational rearrangements associated with Panx1 channel gating
Biophysical Journal, 2023Jacqueline J. Ehrlich +2 more
openaire +1 more source
A novel heterozygous variant in PANX1 causes primary infertility due to oocyte death
Journal of Assisted Reproduction and Genetics, 2022Juepu Zhou, Meng Wang, Lixia Zhu
exaly