Results 191 to 200 of about 111,709 (349)

Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme [PDF]

, 2006
Kiira Ratia, Kumar Singh Saikatendu, Bernard D. Santarsiero, Naina Barretto, Susan C. Baker, Raymond C. Stevens, Andrew D. Mesecar   +6 more
openalex   +1 more source

Astrocyte MCT1 Expression Does Not Contribute to the Axonal Degenerative Phenotype Observed With Ubiquitous MCT1 Depletion

Glia, Volume 74, Issue 2, February 2026.
Loss of astrocytic MCT1 does not cause late onset neurodegeneration. As ubiquitous MCT1 deletion causes axonal degeneration, oligodendrocytes and potentially other cells are more prominent drivers of MCT1‐mediated metabolic support of neurons. ABSTRACT We recently reported that the loss of oligodendrocyte metabolic support through the lactate and ...
Thomas Philips, Emily G. Thompson, Olivia Spead, Balaji G. Vijayakumar, Erica R. Kent, Sean J. Miller, Treasure Nwokeleme, Svetlana Vidensky, Mohamed Hassan Farah, Jeffrey D. Rothstein   +9 more
wiley   +1 more source

Deficiency of Microglial‐Derived Spp1 Exacerbates Age‐Related Memory Decline by Impairing Mitochondrial Complex I Function

Aging Cell, Volume 25, Issue 2, February 2026.
Microglia‐derived Spp1 regulates OXPHOS via the AKT/Complex I pathway to mitigate age‐related memory decline. (Graphical Abstract was created using BioRender). ABSTRACT Age‐related memory decline is a hallmark of brain aging and a primary risk factor for neurodegenerative disorders.
Meiling Wang, Yumin Chang, Aojie He, Jing Yang, Ang Li, Hongqin Wang, Kah‐Leong Lim, Xing Guo, Chengwu Zhang, Li Lu   +9 more
wiley   +1 more source

Structural and Functional Properties of Bromelain, Ficin, and Papain Immobilized on the Stimulus-Sensitive Polymer Poly(N,N-dimethylaminoethyl Methacrylate) [PDF]

A. N. Dubovitskaya, M. G. Holyavka, Maria S. Lavlinskaya, А. В. Сорокин, Maxim S. Kondratiev, А. Н. Лукин, V. G. Artyukhov   +6 more
openalex   +1 more source

3D‐Printed Microfluidic Bioreactor Incorporating Electrospun Scaffolds for Creating an Enhanced Kidney Epithelial Cell Microenvironment

Journal of Applied Polymer Science, Volume 143, Issue 1, January 5, 2026.
Overview of cell seeding, attachment and scaffold insertion into bioreactor, with potential analyses listed after conditioning period. ABSTRACT Chronic kidney disease stands as a significant global health challenge, exacerbated by an ongoing scarcity of available organs for transplantation.
Todd P. Burton, Andrew P. Johnston, Alison McDonald, Rhiannon Grant, Anthony Callanan   +4 more
wiley   +1 more source

Optimization study of ultrasound-assisted polyphenol extraction from cocoa powder and utilization of its grounds using papain solution. [PDF]

, 2016
Noor Ariefandie Febrianto, Teguh Wahyudi
openalex   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju, Tao Zhang, Jianchen Cui, Yulim Lee, Suho Lee, Ho Min Kim, Boohwi Hong, Jiho Park, Chul Hee Choi, Hyon‐Seung Yi, Jun Young Heo, Woosuk Chung   +11 more
wiley   +1 more source

The Carboxyl-terminal Sequence of Papain

, 1962
Albert Light
openalex   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, Volume 13, Issue 1, 5 January 2026.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source