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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19, is a novel human betacoronavirus that is rapidly spreading worldwide. The outbreak currently includes over 3.7 million cases and 260,000 fatalities.
Brendan T. Freitas +8 more
semanticscholar +1 more source
Papain is a proteolytic enzyme present in the leaves, fruits, roots, and latex of the Carica papaya (papaya) plant. Although it exhibits a wide range of activities, there are no reports on the anti-obesity effects of papain.
Yun-Mi Kang +4 more
semanticscholar +1 more source
Evidence of β-sheet structure induced kinetic stability of papain upon thermal and sodium dodecyl sulphate denaturation [PDF]
Papain is a protease that consists of α-helical and β-sheet domains which unfold almost independently. Both, papain considerable thermal stability and sodium dodecyl sulphate (SDS) resistance have been shown.
Rašković Brankica +3 more
doaj +1 more source
IMMOBILIZATION OF PAPAIN ON CHITOSAN
In this study, papain was immobilized on chitosan with Mg(II) cosslinked agent. Studies on free and immobilized papain systems for determination of optimum pH, optimum temperatur, thermal stability and reusability were carried out.
Sari Edi Cahyaningrum +3 more
doaj +1 more source
Although various conjugates of single-walled carbon nanotubes (SWNTs) and biomolecules, such as nanobiosensors and nanobiodevices, have been reported, the conjugation of papain and SWNTs have not been reported because of the formation of unexpected ...
Masaki Kitamura, Kazuo Umemura
doaj +1 more source
Chemical septoplasty using papain enzyme—a feasibility study
Background Though surgery can correct nasal septal defects through a procedure called septoplasty, many people seek non-surgical options. Papain enzyme has been used in the past to lyse intervertebral disc and has shown to have a lytic effect on ...
Arun Angelo Patil +3 more
doaj +1 more source
Utilizing osteocyte derived factors to enhance cell viability and osteogenic matrix deposition within IPN hydrogels [PDF]
Many bone defects arising due to traumatic injury, disease, or surgery are unable to regenerate, requiring intervention. More than four million graft procedures are performed each year to treat these defects making bone the second most commonly ...
Hoey, David A. +2 more
core +1 more source
Optimization of macromolecular prodrugs of the antitumor antibiotic adriamycin [PDF]
In our earlier work [10] on aminoribosyl-bound prodrugs of adriamycin (ADR) using poly(α-l-glutamic acid) (PGA) grafted in high yield (90–100 mol.%) with various peptide spacers as a plasma-soluble macromolecular carrier we observed rather low cytotoxic ...
Feijen, J. +6 more
core +2 more sources
An effort to improve the bonding between bracket and tooth surface is required. Objective: The aim of this studywas to evaluate the effect of papain gel on tensile bond strength (TBS) and adhesive remnant index (ARI) of the orthodontic brackets. Methods:
Niswati Fathmah Rosyida +2 more
doaj +1 more source
In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris [PDF]
We examined the mechanism of action and compared the anthelmintic efficacy of cysteine proteinases from papaya, pineapple, fig, kiwi fruit and Egyptian milkweed in vitro using the rodent gastrointestinal nematode Heligmosomoides polygyrus.
Behnke, J.M. +4 more
core +3 more sources

