Results 121 to 130 of about 666,834 (274)

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]

, 2010
The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter
core   +1 more source

Influence of Nanomaterials and Nanocomposites on the Nutrient Composition

Food Safety and Health, EarlyView.
Nanomaterials and nanocomposites enhance crop nutrition and food quality by improving nutrient availability, plant uptake, and bioavailability through controlled delivery and nano‐encapsulation. Their applications in agriculture and food systems enable sustainable biofortification, improved preservation, and functional foods, while emphasizing safety ...
Akanksha Dwivedi, Roohi Yusufi, G. N. Darwhekar, Kuldeep Vinchurkar, Vijay R. Chidrawar   +4 more
wiley   +1 more source

A dual-tracer method for differentiating transendothelial transport from paracellular leakage in vivo and in vitro

Frontiers in Physiology, 2012
Inflammation-induced impaired function of vascular endothelium may cause leakage of plasma proteins that can lead to edema. Proteins may leave the vascular lumen through two main paracellular and transcellular pathways.
Nino eMuradashvili, Reeta eTyagi, David eLominadze   +2 more
doaj   +1 more source

LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. [PDF]

, 2015
The blood-brain barrier (BBB) is a term used to describe the unique properties of central nervous system (CNS) blood vessels. One important BBB property is the formation of a paracellular barrier made by tight junctions (TJs) between CNS endothelial ...
Arnold, Thomas D, Daneman, Richard, Derugin, Nikita, Lee, Seo Yeon, Lin, Christina, Munji, Roeben N, Ruderisch, Nadine, Sohet, Fabien, Soung, Allison, Vexler, Zinaida S, Yen, Frances T   +10 more
core   +2 more sources

Paracellular permeability of corneal and conjunctival epithelia.

Investigative ophthalmology & visual science, 1989
The paracellular permeability of normal rabbit cornea and conjunctiva was studied in vivo and in vitro. After intravenous administration, horseradish peroxidase was found to percolate to the intercellular space of conjunctival epithelia and was restricted by the tight junctions of the superficial epithelium.
A J, Huang, S C, Tseng, K R, Kenyon
openaire   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

Solvent drag measurement of transcellular and basolateral membrane NaCl reflection coefficient in kidney proximal tubule. [PDF]

, 1991
The NaCl reflection coefficient in proximal tubule has important implications for the mechanisms of near isosmotic volume reabsorption. A new fluorescence method was developed and applied to measure the transepithelial (sigma NaClTE) and basolateral ...
Fushimi, K, Shi, LB, Verkman, AS
core  

Uptake and transport of novel amphiphilic polyelectrolyte-insulin nanocomplexes by caco-2 cells - towards oral insulin [PDF]

, 2011
“The original publication is available at www.springerlink.com”. Copyright SpringerPurpose: The influence of polymer architecture on cellular uptake and transport across Caco-2 cells of novel amphiphilic polyelectrolyte-insulin nanocomplexes was ...
A Bayat, A Jintapattanakit, A Lin, AF Kotzé, AF Kotzé, AF Kotzé, AF Kotzé, Alastair McKinnon, AMM Sadeghi, CJ Thompson, CJ Thompson, CJ Thompson, CM Lehr, CM Lehr, Colin Thompson, F Qian, G Ranaldi, Gillian Smith, H Gersdorff von, IM Lubben van der, JH Hamman, JJH Chu, JP Bai, Karen Skene, KS Soppimath, L Yin, M Bendayan, M Mahkam, M Simon, M Simon, M Thanou, M-K Kim, Mhairi Smith, MM Thanou, N Nishiyama, NJ Kavimandan, P Artursson, Pramod Gadad, PS Pourhosseini, Rachel Knott, RJ Schilling, S Mao, S Sakuma, T Jung, Woei Ping Cheng, X Boulenc, Y-Y Huang   +46 more
core   +1 more source

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source