Estimates of Paracetamol Poisoning in Brazil: Analysis of Official Records From 1990s to 2020 [PDF]
Frontiers in Pharmacology, 2022 Objective: To assess the cases of paracetamol poisoning in Brazil. Methods: Analysis of official records of deaths between 1996 and 2019 from the Brazil Mortality Information System (SIM), admissions between 2008 and 2020 from the Hospital Information ...
Okuyama JHH, Galvao TF, Silva MT
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Pattern of Paracetamol Poisoning: Influence on Outcome and Complications [PDF]
Toxics, 2018 Acute paracetamol poisoning due to a single overdose may be effectively treated by the early administration of N-acetylcysteine (NAC) as an antidote.
Diego Castanares-Zapatero +5 more
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Assessing the Effect of Leptin on Liver Damage in Case of Hepatic Injury Associated with Paracetamol Poisoning [PDF]
Gastroenterology Research and Practice, 2015 Background Aim. In case of high-dose acetaminophen intake, the active metabolite can not bind to the glutathione, thereby inducing cellular necrosis through binding to the cytosol proteins.
Murat Polat +6 more
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Therapeutic effect of WGO in reducing the toxic effect of paracetamol on blood cells and hepato-nephro activity in male rats [PDF]
Open Veterinary JournalBackground: Paracetamol (also called acetaminophen) overdose induces hepatotoxicity that can lead to liver failure. Liver poisoning occurs as a result of paracetamol poisoning when a toxic dose of paracetamol is taken, as the liver loses the ability to ...
Moayad Mijbil Ubaid +3 more
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Evaluation of cut-off values in acute paracetamol poisoning for safe termination of N-acetylcysteine [PDF]
BMC Pharmacology and ToxicologyBackground The Rumack-Matthew nomogram has been utilized to predict hepatotoxicity from acute paracetamol poisoning. Where paracetamol concentrations are unavailable, the commencement and cessation of treatment rely on reported dose.
Jeeyong Lim, Kyungman Cha
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Parental awareness and practices regarding paracetamol use in children: A cross-sectional study from Pakistan. [PDF]
PLOS Global Public HealthParacetamol is the one of the most widely administered drug as an analgesic and antipyretic due to its efficacy, safety, and over-the-counter (OTC) nature and is present in various pharmaceutical forms.
Muhammad Saad Nadeem Butt, Sana Shah
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Keracunan Parasetamol Pada Kucing Dan Anjing: Gejala Klinis dan Terapi
Jurnal Ilmu Peternakan dan Veteriner Tropis, 2020 Acetaminophen, commonly known as paracetamol, is a non-steroidal anti-inflammatory drug commonly used in human medicine for its antipyretic and analgesic action.
Yanuartono Yanuartono +5 more
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On the Treatment of Acute Poisoning With Paracetamol
Неотложная медицинская помощь, 2022 BACKGROUND Currently, despite the optimization of diagnostic methods in order to predict the development of liver damage, improvement of treatment protocols, paracetamol poisoning is a serious problem in medicine, being the most common cause of acute ...
A. Yu. Simonova +6 more
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Acute Paracetamol Poisoning [PDF]
BMJ, 1970 Of 41 cases of acute paracetamol poisoning one died of gastrointestinal haemorrhage and acute massive necrosis of the liver, three became jaundiced, and 13 others had biochemical evidence of hepatocellular damage. Liver damage is a toxic effect which is present in most patients who ingest more than 15 g. of paracetamol.
A T, Proudfoot, N, Wright
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Toxicology Reports, 2022 Paracetamol, also known as acetaminophen (N-acetyl-para-aminophenol, APAP) is the world’s most used over-the-counter analgesic-antipyretic drug. Despite its good safety profile, acetaminophen can cause severe hepatotoxicity in overdose, and poisoning ...
Samuel James Offor +4 more
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