Results 51 to 60 of about 3,013,242 (348)

Testing the paradigm of adiabaticity

open access: yes, 2004
We introduce the concepts of adiabatic (curvature) and isocurvature (entropy) cosmological perturbations and present their relevance for parameter estimation from cosmic microwave background anisotropies data.
Durrer, R., Trotta, R.
core   +1 more source

BMS invariance and the membrane paradigm [PDF]

open access: yes, 2016
The Bondi-van der Burg-Metzner-Sachs (BMS) group is the asymptotic symmetry group of asymptotically flat spacetime. It is infinite dimensional and entails an infinite number of conservation laws.
Penna, Robert F.
core   +2 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

A new paradigm for classifying and treating HER2‐positive breast cancer

open access: yesCancer Reports, 2023
Background Because of the phenomenal success of treatment with monoclonal antibodies and antibody‐drug conjugates targeting human epidermal growth factor receptor 2 (HER2), most patients with early‐stage HER2‐positive breast cancer (HER2+ BC) and some ...
Xuexin He   +2 more
doaj   +1 more source

A new paradigm for monetary policy? [PDF]

open access: yes, 2013
Keynote speech to Conference “Twenty Years of Transition – Experiences and Challenges”. Central Bank of Slovakia.
Issing, Otmar
core   +1 more source

The Citizenship Paradigm [PDF]

open access: yesCambridge Yearbook of European Legal Studies, 2013
AbstractThis chapter suggests the deployment of the concept of European citizenship as a means of integration alongside the internal market, proposing the citizenship paradigm of European integration to inform the Union’s future. This proposal, based on a combination of the initial promise of European unity and the potential of EU citizenship, is not ...
openaire   +4 more sources

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

The new urban paradigm [PDF]

open access: yes, 2018
This paper argues in favor of a new urban model that harnesses the power that cities have to curb global warming. Such a model tackles fundamental management challenges in the energy, building and transport sectors to promote the growth of diverse and ...
Bauer, Steffen   +4 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy