Results 71 to 80 of about 33,400 (300)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Dynamic Modeling and Response Analysis of an Optical Machining Robot with Prismatic Joint Clearance
Applied SciencesThe accuracy and stability of robotic systems are significantly influenced by joint clearances, especially in precision applications like optical mirror polishing.
Shuaishuai Zhu +3 more
doaj +1 more source
International Journal of Advanced Robotic Systems, 2014 This paper presents a comparison study of two important three-degree-of-freedom (DOF) parallel manipulators, the Sprint Z3 head and the A3 head, both commonly used in industry. As an initial step, the inverse kinematics are derived and an analysis of two
Xiang Chen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Jixie chuandong, 2013 The dynamic planning of the flexible parallel manipulators is discussed.Firstly the kinematics of the flexible parallel manipulator is analyzed.Secondly,the mathematical model of driving torque minimum was development.Finally,the dynamic planning of ...
丁明, 刘善增
doaj
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Simulation of the Lumbar Spine as a Multi-Module Paralel Manipulator
Applied Bionics and Biomechanics, 2011 In this paper a simulation of movements of lumbar spine is proposed by using a model with serially connected parallel manipulators. An analysis has been computed for the human spine structure and its movements, in order to simulate the motions and forces
M. Ceccarelli +3 more
doaj +1 more source
, 1988 A space spider crane for the movement, placement, and or assembly of various components on or in the vicinity of a space structure is described. As permanent space structures are utilized by the space program, a means will be required to transport cargo ...
Bryan, Charles F., Jr. +4 more
core +1 more source
Computation of parallel link manipulator dynamics
Proceedings of IECON '93 - 19th Annual Conference of IEEE Industrial Electronics, 1994 This paper proposes an algorithm, for calculating the inverse dynamics of link manipulators. First, we derive a method to calculate the inverse dynamics of a general type of parallel link mechanism using the method proposed by Luh and Zeng., which is developed for a simple closed link mechanism and yields the inverse dynamics of the simple closed link ...
Kazuhiro Kosuge +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source