Results 71 to 80 of about 181,181 (303)
Actuation Spaces Synthesis of Lower-Mobility Parallel Mechanisms Based on Screw Theory
Chinese Journal of Mechanical Engineering, 2021 The lower-mobility parallel mechanism has been widely used in the engineering field due to its numerous excellent characteristics. However, little work has been devoted to the actuator selection and placement that best satisfy the system’s functional ...
Shihua Li +3 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Motion planning of a climbing parallel robot [PDF]
, 2003 This paper proposes a novel application of the Stewart–Gough parallel platform as a climbing robot and its kinematics control to climb through long structures describing unknown spatial trajectories, such as palm trunks, tubes, etc.
Almonacid Kroeger, Miguel +3 more
core +3 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Design and Isokinetic Training Control Method of Leg Press Training Device
Applied Sciences, 2019 Lower-limb function in elderly people gradually degenerates with age, and poor rehabilitation conditions preventing the elderly from receiving scientific rehabilitation training result in the decline of social labor force and the increased economic ...
Hongfei Yu +4 more
doaj +1 more source
Dynamics of the Orthoglide parallel robot [PDF]
, 2009 Recursive matrix relations for kinematics and dynamics of the Orthoglide parallel robot having three concurrent prismatic actuators are established in this paper.
Chablat, Damien +2 more
core +2 more sources
Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Kinematic Analysis and Calibration Experiment of a 2UPU-SP+RR Hybrid Robot
IEEE AccessHybrid robots integrate the advantages of both serial and parallel mechanism, demonstrating significant potential for complex surface machining of aluminum alloys.
Xiaoyu He +3 more
doaj +1 more source
Design and Analysis of a Lower Limb Rehabilitation Training Component for Bedridden Stroke Patients
Machines, 2021 Carrying out the immediate rehabilitation interventional therapy will better improve the curative effect of rehabilitation therapy, after the condition of bedridden stroke patients becomes stable.
Xusheng Wang +6 more
doaj +1 more source